Function
Together with two further proteins McbF and McbG this protein causes immunity to the peptide antibiotic microcin B17 (MccB17), which inhibits DNA replication in enterobacteriaceae. Immunity is determined by two different mechanisms. McbE is involved in the production of extracellular MccB17 and, in a complex with McbF it also serves as pump for the export of active MccB17 from the cytoplasm to the periplasmic space.