Protein
Mating-type M-specific polypeptide Mc
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Function
Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Positive regulator of MFM genes. The HMG box recognizes the DNA sequence 5'-AACAAAG-3'. Required for conjugation and efficient meiosis.
Sequence
MDSHQELSAGSPISYDFLDPDWCFKRYLTKDALHSIETGKGAAYFVPDGFTPILIPNSQSYLLDGNSAQLPRPQPISFTLDQCKVPGYILKSLRKDTTSTERTPRPPNAFILYRKEKHATLLKSNPSINNSQVSKLVGEMWRNESKEVRMRYFKMSEFYKAQHQKMYPGYKYQPRKNKVKR