lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1177 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

129.12 kDa

MRRAGRSRQFSSVEEAFSTSAARPGRRGRRSGRENTAKFVPATLSASTSFSRIEGISSRSVTLASPGSRSGSGPRSGPRLGPANRSTSRYRWVPAAAGWTVGVIATVSLLGSVSPLIRYLIKVPREFINDYLFNFPDTSIAWSFVLALLAAALTARKRIAWLLLLGNMILAAALNVADIAAGDNTAAEIFGENLGFAVHIVAIVLLVLAYREFWAKVRKGALVKAAAVLVAGDVVGILVSWGLVELFPGTLARQDRLPYVVNRVVGFALADPDLFTGRPHVFLNAIFGLFGALALIMATIVLFQSQRAENALTGEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAQSGRAAITYRVEIGVCLASGDPIGDPRAWPQAVDAWLGLCQTYGWAPGVMGASTQGARTYREAGLNALELGDEAILRTSEFKLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISPEAMADTIARADAWRDTQTERGFSMALGRLGDPADGDCLLVEAIDRDGSVVAMLSLVPWGTTGVSLDLMRRSPSSPNGTIELMVSELALNAESLGITRISLNFAMFRSAFEQGAQLGAGPVARLWRGLLLFFSRWWQLETLYRSNMKYQPDWVPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRDKVHTGHHPAVPARLAQSGLLHHDGSAPDVSGLRPERTDAEEARSRLPEQVRVRLAKLKVLQRNGVDAYPVGCPPSHTVAQALDADDQQDITVAGRILRIRDFGGVLFAQLRDWSGEMQVLLDNSRLERGRTADFTAAIDLGDLVEVSGQMGFSKKGTRSLIVTDWRMIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNPESRELIAARSEVLRSVRQTLFAKGFIEVETPILQQIHGGATARPFVTHINTYDMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYRVWIDGCRELIQNAAQAAHGEQTVLRPGADGRLQPVDISGIWAVKTVHDAVSEALGEQVDPGTSLSTLRKLSDAARIPYRAHWDAGAVVLELYEHLVEDRTEEPTFYVDFPTSVSPLTRPHRSRPGVAERWDLVAWGVELATAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRLVMLITGRSIRETLPFPLAKPH

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1177 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

129.146 kDa

MRRAGRSRQFSSVEEAFSTSAARPGPRGRRSGRENTAKFVPATLSASTSFSRIEGISSRSVTLASPGSRSGSGPRSGPRLGPRNRSTSRYRWVPAAAGWTVGVIATVSLLGSVSPLIRYLIKVPREFINDYLFNFPDTSIAWSFVLALLAAALTARKRIAWLLLLGNMILAAALNVADIAAGDNTAAEIFGENLGFAVHIVAIVLLVLAYREFWAKVRKGALVKAAAVLVAGDVVGILVSWGLVELFPGTLARQDRLPYVVNRVVGFALADPDLFTGRPHVFLNAIFGLFGALALIMATIVLFQSQRAENALTGEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAQSGRAAITYRVEIGVCLASGDPIGDPRAWPQAVDAWLGLCQTYGWAPGVMGASTQGARTYREAGLNALELGDEAILRTSEFKLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISPEAMADTIARADAWRDTQTERGFSMALGRLGDPADGDCLLVEAIDRDGSVVAMLSLVPWGTTGVSLDLMRRSPSSPNGTIELMVSELALNAESLGITRISLNFAMFRSAFEQGAQLGAGPVARLWRGLLLFFSRWWQLETLYRSNMKYQPDWVPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRDKVHTGHHPAVPARLAQSGLLHHDGSAPDVSGLRPERTDAEEARSRLPEQVRVRLAKLKVLQRNGVDAYPVGCPPSHTVAQALDADDQQDITVAGRILRIRDFGGVLFAQLRDWSGEMQVLLDNSRLERGRTADFTAAIDLGDLVEVSGQMGFSKKGTRSLIVTDWRMIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNPESRELIAARSEVLRSVRQTLFAKGFIEVETPILQQIHGGATARPFVTHINTYDMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYRVWIDGCRELIQNAAQAAHGEQTVLRPGADGRLQPVDISGIWAVKTVHDAVSEALGEQVDPGTSLSTLRKLSDAARIPYRAHWDAGAVVLELYEHLVEDRTEEPTFYVDFPTSVSPLTRPHRSRPGVAERWDLVAWGVELATAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRLVMLITGRSIRETLPFPLAKPH

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1174 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

128.396 kDa

MGVGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPGISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASVSPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLVLLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREFWAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANRVVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALTGEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLTALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDEMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLAMLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLNFAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSSGIDAFPVGRPPSHTVAQALAADHQASVSVSGRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASKTGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRALITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDISGIWPVRTVHDAISEALGERIDADTGLTTLRKLCDAAGVPYRTQWDAGAVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAWGIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1172 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

128.24 kDa

MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPGISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASVSPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLVLLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREFWAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANRVVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALTGEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLTALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDEMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLAMLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLNFAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSSGIDAFPVGRPPSHTVAQALAADHQASVSVSGRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASKTGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRALITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDISGIWPVRTVHDAISEALGERIDADTGLTTLRKLCDAAGVPYRTQWDAGAVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAWGIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1172 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

128.24 kDa

MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPGISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASVSPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLVLLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREFWAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANRVVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALTGEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLTALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDEMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLAMLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLNFAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSSGIDAFPVGRPPSHTVAQALAADHQASVSVSGRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASKTGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRALITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDISGIWPVRTVHDAISEALGERIDADTGLTTLRKLCDAAGVPYRTQWDAGAVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAWGIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1172 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

128.24 kDa

MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPGISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASVSPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLVLLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREFWAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANRVVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALTGEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLTALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDEMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLAMLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLNFAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSSGIDAFPVGRPPSHTVAQALAADHQASVSVSGRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASKTGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRALITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDISGIWPVRTVHDAISEALGERIDADTGLTTLRKLCDAAGVPYRTQWDAGAVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAWGIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1172 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides.

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

128.24 kDa

MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPGISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASVSPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLVLLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREFWAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANRVVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALTGEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLTALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDEMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLAMLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLNFAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSSGIDAFPVGRPPSHTVAQALAADHQASVSVSGRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASKTGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRALITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDISGIWPVRTVHDAISEALGERIDADTGLTTLRKLCDAAGVPYRTQWDAGAVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAWGIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1172 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

128.182 kDa

MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPGISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASVSPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLVLLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREFWAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANRVVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALTGEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLTALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDEMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLAMLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLNFAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSSGIDAFPVGRPPSHTVAQALAADHQASVSVSGRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASKTGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRALITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHAGYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDISGIWPVRTVHDAISEALGERIDADTGLTTLRKLCDAAGVPYRTQWDAGAVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAWGIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1172 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

128.196 kDa

MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPGISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASVSPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLVLLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREFWAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANRVVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALTGEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLTALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDEMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLAMLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLNFAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSSGIDAFPVGRPPSHTVAQALAADHQASVSVSGRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAAEFNAATDLGDLVEMTGHMGASKTGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRALITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHAGYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDISGIWPVRTVHDAISEALGERIDADTGLTTLRKLCDAAGVPYRTQWDAGAVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAWGIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1172 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

128.196 kDa

MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPGISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASVSPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLVLLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREFWAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANRVVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALTGEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLTALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDEMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLAMLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLNFAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSSGIDAFPVGRPPSHTVAQALAADHQASVSVSGRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAAEFNAATDLGDLVEMTGHMGASKTGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRALITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHAGYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDISGIWPVRTVHDAISEALGERIDADTGLTTLRKLCDAAGVPYRTQWDAGAVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAWGIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1138 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

125.686 kDa

MALDTPSSDLPVSTDDTAEHQPTPAHRPPSAADRRSVDLLEKIRRPRGFGAGAPKIAGTVVGVLAGIALLSSIFPLFRRLIHYPRDFIDNYIVSLPNTSLAWAFVLALVAIALSSRKRIAWWIATIYLVLFMVSNALLLVDPVATDFGVDTDERIQIWIGLGIDAAALIFLIVTYRQFYTRVRRGALFRALGVLIVGLTAATLVGWGLVWAWPGSLERTERLPYAFNRVVTFGSIDSRTFDGHHTHIVIDSALGLLGALALIAAATVLFRSQRLESLMTSDDEKLIRALITRFNDDDSLAYFSTRRDKAVVFSPDGRAAITYRVEIGVGLAGGDPIGDPESWPDAIAEFLTLCDRYGWHPAAMGSSARGAAAYDAAGFGSLSIGDEAILHTREYTISGPAMKAVRQAVTRTRRAGVTVRIRRHGEVPDDEMPQVIARADAWRDTDEERGFAMALSRLGDRADDDCLLVEAVEHAGTPEEKVIGMLSFVPWGRRGVSLDVMRRDRGSVNGVVETMVTELCRNSEQFGITEISLNFATFRAFFEQGPQIGAGPIMRLGYSVLMFGSRFFQMESLYKSNAKYLPDWQPRFLCFEDNRILPRVGLAAIVTEGFVQLPRFGRKQHYIAGQSSIPAGVDADALIAQLESEEDRTAVEVHRPEQVRVRVAKLDRLIEEGFDPYPPADAPTHTIAEAIAEPEGTQVTIAGRVTKMRDFGKVTFADVHDWSGQIQMLVEASRVIPGTPDFGSDVDLGDLVEARGVIGRSRSGELSVLIDAWRFNGKCLRPLPDKWSGLTDPEARVRQRYVDLAINPRSRELLATRSVVVKALRDFLADRGFMEVETPILQQIHGGANATPFQTHINAYNLDLYLRIAPELYLKRLCVGGVEKVFEIGRNFRNEGVDFSHNPEFTSLEAYAAHSDYLKMLDLTREMIQHAATAAHGEPVIIRVDDEGNEQRVDISGDWPVRTVHEVVSEGAGVEITSDTEVSELRGICDRLEIAYRPDWDAGQIVLELYEHLGEDRTTVPTFYTDFPTSTSPLTRAHRSKPGVAERWDLVAWGVELGTAYTELTDPVEQRKRLTAQSILAADGDPEAMELDEDFLTALEYAMPPTGGLGVGVDRVVMLITGQSIRESLAFPMVKPTDA

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1133 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

124.424 kDa

MTTVDASPGISRFEGISSRSVTVATICSGPCSGSRSHSRYHWVPAAAGWTVGVIATLSLIASVSPLIRWLIRVPREFINNYLFNFPDTSIAWSFVLALLAAALTTRKRIAWLLLLGNMVLAAVLNAVDMAANGNTPAETFGENLGFAVHVVAILLLVLSYREFWAKVRRGALFKAAAVLVAGDVIGILLSLGLVELFPGSLARQDRLPYVANRVVGFALADPDLFSGKPHVLLNAIFGLFGALALIMATIVLFQSQRADNALTGEDESAIRGLLELYGKNDSLGYFATRRDKSVIFAHNGRAAITYRVEIGVCLASGDPVGDPGAWPQAVDAWLELCQTYGWAPGVMGASSQGAQVFRRAGFNAIELGDEAILRTAVYKLSGPDMRGVRQAVTRARRAGLTVRIRRHSDISANEMADTIARADAWRDTEFERGFSMALGRLGDPADSDCLLVEAVDRDDHVVAILSLVPWGTTGVSLDVMRRSPQSPNGTIELMVSELALKGETLGIARISLNFTMFRAAFEQGAQLGAGPIARLWRGLLLFFSRWWQLETLYRSNIKYLPDWVPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRGRVHTGHHPAVPARLAESGLLHHDGSTPDVSGLQTADVDLEVANSRIPEQVRVRLAKLKTLQLNGIDAYPVGHPPSHTVAQALDADDEGTVSISGRILRIRDYGGVLFAHVRDWSGEIQVLLDNLVLECCCIADFTAAIDLGDIVEMTGNMGFSKNGTRSLIVRNWRLIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNTESRNLIMARSCVLRSVREMLFAKGFVEVETPILQQIHGGATARPFATRINTYDMDLFLRIAPELYLKRLCIGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYLMWIDGCRELIQNAAEAANGTQTLMRPRIEGASGTANHLEPIDISGVWPVKTVYEAVSEALGECVDTSTELATLRKLSDAAHIPYWPHWDTGAVVLKLYEHLVENRTDQPTFYIDFPTSVSPLTRPHRSKPGVAERWDLVAWGIELGTAYSELTDPVEQRRRLHEQSLLAVGGNPEAMELDEDFLQAMEYAMPPTGGLGMGIDRLVMLITGRSIRETLPFPLAKPH

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1133 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

124.424 kDa

MTTVDASPGISRFEGISSRSVTVATICSGPCSGSRSHSRYHWVPAAAGWTVGVIATLSLIASVSPLIRWLIRVPREFINNYLFNFPDTSIAWSFVLALLAAALTTRKRIAWLLLLGNMVLAAVLNAVDMAANGNTPAETFGENLGFAVHVVAILLLVLSYREFWAKVRRGALFKAAAVLVAGDVIGILLSLGLVELFPGSLARQDRLPYVANRVVGFALADPDLFSGKPHVLLNAIFGLFGALALIMATIVLFQSQRADNALTGEDESAIRGLLELYGKNDSLGYFATRRDKSVIFAHNGRAAITYRVEIGVCLASGDPVGDPGAWPQAVDAWLELCQTYGWAPGVMGASSQGAQVFRRAGFNAIELGDEAILRTAVYKLSGPDMRGVRQAVTRARRAGLTVRIRRHSDISANEMADTIARADAWRDTEFERGFSMALGRLGDPADSDCLLVEAVDRDDHVVAILSLVPWGTTGVSLDVMRRSPQSPNGTIELMVSELALKGETLGIARISLNFTMFRAAFEQGAQLGAGPIARLWRGLLLFFSRWWQLETLYRSNIKYLPDWVPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRGRVHTGHHPAVPARLAESGLLHHDGSTPDVSGLQTADVDLEVANSRIPEQVRVRLAKLKTLQLNGIDAYPVGHPPSHTVAQALDADDEGTVSISGRILRIRDYGGVLFAHVRDWSGEIQVLLDNLVLECCCIADFTAAIDLGDIVEMTGNMGFSKNGTRSLIVRNWRLIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNTESRNLIMARSCVLRSVREMLFAKGFVEVETPILQQIHGGATARPFATRINTYDMDLFLRIAPELYLKRLCIGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYLMWIDGCRELIQNAAEAANGTQTLMRPRIEGASGTANHLEPIDISGVWPVKTVYEAVSEALGECVDTSTELATLRKLSDAAHIPYWPHWDTGAVVLKLYEHLVENRTDQPTFYIDFPTSVSPLTRPHRSKPGVAERWDLVAWGIELGTAYSELTDPVEQRRRLHEQSLLAVGGNPEAMELDEDFLQAMEYAMPPTGGLGMGIDRLVMLITGRSIRETLPFPLAKPH

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1128 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

124.152 kDa

MDNPPPTGVAPRHLPPGSVHTGKVTASLSHRRPDSVQDAPPAPVPHRAHGRLREVPHIAGLVLGVFAVACLLWSLSPALRFLTGPPRRFVDDYYFDAPDTNVMWALIVGLLAGAIASRKRIAWWLLVGYLTLFAVANGLRFAAEQNINALVAMIVQVGVVGLLIAAWPEFYTRVRRGAGWKALGVLVGGLAIGCLLGWGLVEVFPGSLPPGWQRPGWAVYRVTAAILVENEHFGGHPRPFVNVLLGLFGAIALLAAVLTLLRSQRAANAMTGLDESAIRGLLEHSDVEDSLGYFATRRDKAVVFAPSGKAAVTYRVELGVCLASGDPVGVREAWPHAIDAWLRLADRFGWTPAVMGASEEGATAYRRAGLSALRLGDEAVLDTRDFSLAGPELRQVRQAANRLRKQGVRVRIRRHREIPSAEFEQIMARADAWRDTETERGFSMALGRLGDPLDADCLLVEAVAADDRVLGMLSLVPWGRTGVSLELMRRDPQGPNGVMELMISQLALNSEQFGITRVSLNFAVFRSVFEEGGRIGAGPVLRLWRGVLLFFSRWWQLEALYRSNVKYQPDWVPRFFLFEERRQLPRVAVASALAEGFLPRLGKDPDASAHTGAQSAVPDTLTGLHADGSPPDWPKPDLLDSGPRRPEQVRVRMAKLDRMTAAGVDAYPVAYPPTHTVAAARRSPRGTTVRVCGRLLRIRDYGGVVFALLRDWSDDIQLVIDRERVGAARSAEFGEYFDLGDLIEVSGQIGRSRSGELSLLAADWRMLGKCLHPLPDKWKGLADPEARVRQRYVDMAINPETRDVLAKRSAVVRSLRESLNSWGYLEVETPILQQVHGGANATPFTTHINAYDLDLYLRIAPELYLKRLCVGGMEKVFELGRTFRNEGVDFSHNPEFTILEAYEAHSDYIRMMHTCRVLIQNAALAANGSMVAMRPGADGALEPVDISGDWPVKTVHGAVSAAVGTEITPRTGVAELRELCDRVGVPYQHGWDEGQIVLEMYEHLVEARTEEPTFYVDFPTSVSPLTRAHRSTPGVTERWDLVAWGVELGTAYSELTDPVEQRRRLTEQSVLAANGDPEAMELDEDFLQALEHAMPPTGGLGMGVDRIVMLITGRSIRETLPFPLVKPR

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1114 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

122.363 kDa

MSASTETHHASEAAVPTAPRPRPGLGTKNGRLHQVPHIAGLILGVFSVLVFLWSISPVLRYYVHVPREYVDTYYFDAPDTSLSWALVVALLAAALASRKRIAWWLLTIYLVLFLITNVIVSITDKNVNAMAAAVVQVVLIGILIAARPEFYTRVRRGAGWKALGVLIVGLAIGTLLGWGLVELFPGTLPQNERFLWALNRVTALAAADNEQFTGRPHGFVNTLLGLFGAIALLAAVITLFRAQRSHNALTGNDESALRGLLLQYGADDSLGYFATRRDKAVVFAPSGKAAITYRVELGVCLASGDPIGDPEAWPHAIEEWQALASQYGWATAVMGASETGATAYNKAGLTVLQLGDEAILRTREFNLSGRDMRQVRQAVTRVRRQGVTVRIRRHRDVPAEEMAETIRLADAWRDTETERGFSMALGRLGDRLDGDCLLVEAVAEDGEIDGILSLVPWGPTGVSLDLMRRKPTSPNGVVELMVSELATTSDQFGITKVSLNFAVFRSVFEEGSRIGAGPILRIWRSILVFFSRWWQLEALYRSNVKYQPEWVPRFLCFEDNRELLRVGFASAVAEGFVTLPRFGRSGTRDALEHTGTHAAVPAALVAAEGLHSDGSAPGEGLAPTATGPKRPEQVRVRLDKLAGLAEQGIDPYPVAYPPSHTVTEAVESPEGTTVRIAGRLLRIRDYGGVVFAVVRDWSGDIQILVDEARVGTDRIRAFAAEFDLGDLVEVAGVIGYSRRGALSLLANEWRMTGKCLHPLPDKWKGLSDPETRVRQRYVDLAINSDARRLLEARSAVVKSLRDSLGGRGFLEVETPILQQVHGGANAAPFLTHINAYNLDLYLRIAPELYLKRLCVAGMEKVFEIGRVFRNEGVDFKHNPEFTILEAYEAHSDYEKMMVLCRELIQTAAIAAYGREIIMRPGPDGALVEVDISGEWPVKTMHQAVAEKLGVDVSPETPLTELQRLCDEHEIPYQSTWDAGAVAQEMYEHLVEDYTEFPTFYTNFPTSMSPLTRPHPTIPGVAAKWDLVAWGVELGTAYSELTDPVDQRNRLTEQSMLAAGGDEEAMELDEDFLQALEHAMPPTGGLGMGVDRVVMLITGGSIRETLAFPLAKPRQ

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1114 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

122.292 kDa

MSASTETHHASEAAVPTAPRPRPALGSKSGRLHQVPHIAGLILGVFSVLVFLWSISPVLRYYVHVPREYIDTYYFDAPDTSLSWALVVALLAAALASRKRIAWWLLTIYLVLILITNVIVSITDRNVNAMVAAVVQVVLIGILVAARPEFYTRVRRGAGWKALGVLIVGLAIGTLVGWGLVELFPGTLPQGERFLWALNRVTALAAADNEQFSGRPHGFVNTLLGLFGAMALLAAVITLFRAQRSHNALTGNDESALRGLLLQYGADDSLGYFATRRDKAVVFAPSGKAAITYRVELGVCLASGDPIGDPEAWPHAIEAWQTLASQYGWATAVMGASETGATAYNKAGLTVLQLGDEAILRTREFNLSGRDMRQVRQAVTRVRRQGVTVRIRRHRDVPPEEMAEAIRLADAWRDTETERGFSMALGRLGDRLDGDCLLVEAIAEDGEIDGILSLVPWGPTGVSLDLMRRKPTSPNGVVELMVSELATTSDQFGITKVSLNFAVFRSVFEEGSRIGAGPILRIWRSILVFFSRWWQLEALYRSNVKYQPEWVPRFLCFDDNRELLRVGFASAVAEGFVTLPRFGRSGTHDAIEHTGHHAAVPAALVAAEGLHSDGSAPGEGLAPTATGPKRPEQVRVRLDKLTGLAEQGIDPYPVAYPPSHTVTEAVESPEGTTVRIAGRLLRIRDYGGVVFAVVRDWSGDIQVLVDEARVGTDRIRAFAAEFDLGDLVEVAGVIGYSRRGALSLLANEWRMTGKCLHPLPDKWKGLSDPETRVRQRYVDLAINTDARRLLEARSAVVKSLRDSLGGRGFLEVETPILQQVHGGANAAPFLTHINAYNLDLYLRIAPELYLKRLCVAGMEKVFEIGRVFRNEGVDFKHNPEFTILEAYEAHSDYEKMMVLCRELIQTAAVAAYGREIIMRPGPDGTLVEVDISGEWPVKTMHQAVAEKLGVDVSPETPLAELQRLCDEHEIPYQSTWDAGAVAQEMYEHLVEDYTEFPTFYTNFPTSMSPLTRPHPTIPGVAAKWDLVAWGVELGTAYSELTDPVDQRNRLTEQSMLAAGGDEEAMELDEDFLQALEHAMPPTGGLGMGVDRVVMLITGGSIRETLAFPLAKPRQ

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1112 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

121.837 kDa

MTLTSPPRTRADSRYSWVPAAAGWTVGVIATLSLIASVSPLVRWIIRVPREFVDDYIFNFPDTSFAWAFVLALLAGALAARKRIAWWILLLYMVAAAGWNVADLLTGDESVVDEMGEVIGLAFHLAAVAFLLLARPLFWARVRRGALFKAAGVLAAGMAVGVLVGWGLLELFPGDLERDYRLAYAANRVFAFAGVDPDAFDGQHPHVVVNALLGLFGALALMAAAIVLFQSQRSENALTGEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAPNGRAAITYRVEVGVCLASGDPVGDPKAWPQAIDAWLALCGTYGWAPGVMGASVGGAEAFRAAGLSAIQLGDEAILLPDSFRLSGPDMRAVRQAVTRARRAGVTVRIRRHRELSPEQMAEVIAHADAWRDTETERGFSMALGRLGDPADSDCLLVEAVQGGNGGQERSDPGDGTVVAMLSLVPWGSNGASLDVMRRSPQSPNGTIELMVSELCMQAEDIGVTRISLNFAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPQWVPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRNKQHTGHHTSAPQDLVASGVLHHDGTAPDMSGLRTDTADDEPPRLPEQVRVRMAKLKALQADGVDAYPVGRPPSHTAAAAVDSPDDVELDVAGRVLRIRDYGGVLFAQLRDWSGEVQLLLDNSTLEQGSTADFTAAIDLGDLIAATGTMGYSKNGTRSLLVRHWRLTGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTEARDLIRARSGVLHAIRDTLYHKGFLEVETPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYHVWIDGCRELIQNAAMAANGEHVFLRPRDDGVLEPVDISGPWTVKTVHEAVSEALGEHIDAATELPTLRKLADAAGIPYLTHWDEGAVVLEMYEHLVEDRTQKPTFYKDFPTSVSPLTRPHRSIAGVAERWDLVAWGVELGTAYSELTDPVEQRRRLQAQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLARPR

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1112 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

121.837 kDa

MTLTSPPRTRADSRYSWVPAAAGWTVGVIATLSLIASVSPLVRWIIRVPREFVDDYIFNFPDTSFAWAFVLALLAGALAARKRIAWWILLLYMVAAAGWNVADLLTGDESVVDEMGEVIGLAFHLAAVAFLLLARPLFWARVRRGALFKAAGVLAAGMAVGVLVGWGLLELFPGDLERDYRLAYAANRVFAFAGVDPDAFDGQHPHVVVNALLGLFGALALMAAAIVLFQSQRSENALTGEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAPNGRAAITYRVEVGVCLASGDPVGDPKAWPQAIDAWLALCGTYGWAPGVMGASVGGAEAFRAAGLSAIQLGDEAILLPDSFRLSGPDMRAVRQAVTRARRAGVTVRIRRHRELSPEQMAEVIAHADAWRDTETERGFSMALGRLGDPADSDCLLVEAVQGGNGGQERSDPGDGTVVAMLSLVPWGSNGASLDVMRRSPQSPNGTIELMVSELCMQAEDIGVTRISLNFAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPQWVPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRNKQHTGHHTSAPQDLVASGVLHHDGTAPDMSGLRTDTADDEPPRLPEQVRVRMAKLKALQADGVDAYPVGRPPSHTAAAAVDSPDDVELDVAGRVLRIRDYGGVLFAQLRDWSGEVQLLLDNSTLEQGSTADFTAAIDLGDLIAATGTMGYSKNGTRSLLVRHWRLTGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTEARDLIRARSGVLHAIRDTLYHKGFLEVETPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYHVWIDGCRELIQNAAMAANGEHVFLRPRDDGVLEPVDISGPWTVKTVHEAVSEALGEHIDAATELPTLRKLADAAGIPYLTHWDEGAVVLEMYEHLVEDRTQKPTFYKDFPTSVSPLTRPHRSIAGVAERWDLVAWGVELGTAYSELTDPVEQRRRLQAQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLARPR

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1111 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

121.824 kDa

MTLTSPPRTRADSRHSWVPAAAGWTVGVIATLSLIASVSPLVRWIIRVPREFVNDYIFNFPDTSFAWAFVLALLAGALAARKRIAWWILLLYMVAAVGWNVADLLTGDESVVEEMGEVIGLAFHLAAVAFLLLARPLFWARVRRGALFKAAGVLAAGMAVGVLVGWGLLELFPGDLERDYRLAYAANRVFAFAGVDPDAFDGQHPHVVVNALLGLFGALALMAAAIVLFQSQRSENALTGEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAPNGRAAITYRVEVGVCLASGDPVGDPKAWPQAIDAWLALCGTYGWAPGVMGASVGGAEAFRAAGLSAIQLGDEAILHPDSFRLSGPDMRAVRQAVTRARRAGVTVRIRRHRELSPEQMAEVIAHADAWRDTETERGFSMALGRLGDPADSDCLLVEAVQGETGGERSDPGSGTVVAMLSLVPWGSNGASLDVMRRSPQSPNGTIELMVSELCMQAEDIGVTRISLNFAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPQWVPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRNKQHTGHHTSAPQDLVASGVLHHDGTAPDMSGLRTDTADDEPPRLPEQVRVRMAKLKALQADGVDAYPVGRPPSHTAAAAVDSPDDVELDVAGRVLRIRDYGGVLFAQLRDWSGEVQLLLDNSTLEQGSTADFTAAIDLGDLIEATGTMGYSKNGTRSLLVRHWRLTGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTEARDLIRARSGVLHAIRDTLYHKGFLEVETPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYHVWIDGCRELIQNAAMAANGEHVFLRPRDDGVLEPVDISGPWTVKTVHDAVSEALGEHIDAATELPTLRKLADAAGIPYLTHWDEGAVVLEMYEHLVEDRTEKPTFYKDFPTSVSPLTRPHRSIAGVAERWDLVAWGVELGTAYSELTDPVEQRRRLQAQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLARPR

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1110 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

122.213 kDa

MTSIKPAVEPPAPDHPAVTALPGIGARPAARPPVTSRWRWVPAFFGWFVGIQAILNFLSSISPFIRMVTKLPREFVDEYLFGWPDGSLSWAFVLSLLAAALAVRKSIAWWVLLIDLLGRSALNVGGFIEHRDTTELIGLVVHGAFILLLLLARKEFYAKVRRGATVKAALVLIAGMAAGTVLAWGLLELFPRTLVPGDRFWWALNRVAGFSIASHRDFDGLPPHFLNWLFGLFGALALIAAAIVLFRSQRAVNALTGDDESLIRGLLERYGQDDSLGYFATRRDKAVIFAPNGRAAVTYRVEVGVCLVSADPIGDKSAWGQAISAWLQVCDAYGWAPAVMGASAEGALAYREHGLNALELGDEAILYPRSFSISGPHMATVRQAVNRARRSGLSVRIRRHRELSAEETKQIIVNADLWRDGNTERGFSMALGRLGDSTDGDCLLVEAIDSTGDPVAMLSLVPWGTNGVSLELMRRSRQSPNGTIEFMVTELLTRAEGMGITRVSLNFVMFRSVYADGSRIGAGPVLRLWRSVLMFASRFWQFEQLYRSNVKYQPEWVPRFACYEDARLIPRIGIASVIAEGFLVLPFGNRDKPRHTGQYSAVPQAIVATGLLHHDGSTPELLPQTAPQQRVPEQVKVRLGKLAALQEKGIDTYPVGSPPSHTVAEALAAPDGSEVVISGRLLRIRDYGGVLFAQLRDWSAEVQLLIDDPRLHEEFTAAVDLGDLVEASGVMGQSNNGTRSVLVESWRIIGKCLHPLPDKRKGLTDPEARVRARYLDLAINPEAREQIAARSAIITSLRNTLLAQGFLEVETPILQQVHGGANARPFLTHINAYNLDLYLRIAPELYLKRLCVGGVEKVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYVTWAQTTQRLIQNAAKAAHGAEVVMRPGADGRLAPVDIGGEWPIVPVHEAVSRALGEEVNAATEVPTLQRFCQSAEVQFNPRWDAGHLVLELYERLVEKHTTSPTFYSDFPVSVSPLTRPHRSIAGLAERWDLVAWGVELGTAYTELTDPVEQRRRLYEQSLLAAGGDAEAMELDEDFLRAMEYAMAPTGGMGMGVDRVVMLITGRSIRETLPFPLAKPR

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1106 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

121.219 kDa

MTVISRVEHLPARPASRVAWVPAAAGWTVGVIATLSLIASVSPLVRSLIRVPREFVNDFIFNFPDTSFAWAFVLALLAAALAARKRIAWWVLVLYLVGAIGWNVGDLAAGGDTVADDIGELIGIAFHVAAIVFLVVARKEFWAKVRRGALLKSAAVLVAGNLIGIVVAWGLLQAFPGTLDPEWRLPYAVNRVSGFATVPTEVFEGYSHTFLNAIFGLFGALALMAAAIVLFQSQRASNALTGEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAPNGRAAITYRVEVGVCLASGDPVGDPKSWPQAIAAWLQLCQAYGWAPGVMGASLAGAEAYRAAGLNALQLGDEAILHPDRFRLSGPDMRAVRQAVTRARRAGTSVRIRRHRELSPEEMAAVIRRADAWRDTETERGFSMALGRLGDPADDDCLLVEAVQGDEVVAMLSLVPWGSNGVSLDVMRRSPRSPNGTIELMVSELCMQAEDIGISRISLNFAMFRSAFEQGAQLGAGPVARLWRALLVFFSKWWQLESLYRSNMKYQPEWVPRYACYEDARLVPRVGVASVIAEGFLVLPFSRRNKQHTGEHIAAPDTLVQSGRLHRDGSAPDVTGLQGELPDADDEPRLPEQVRVRMAKLKALQGNGVDAYPVGQPPSHTVAQALGATDGETLSVAGRVMRIRDYGGVLFAQLRDWSGEVQLLLDNAALTEGETADFTATIDLGDLVEVTGSMGFSRNGTRSLLVERWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTEARDLIRARSGALHAIRETLYSKGFLEVETPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYNVWIDGCRELIQNAAQAANGAQVFLRPRPNDPAGTLEPVDISGQWAVKTVHDAVSEAIGEHITPETELGELRRLCDSAGIPYLTHWDAGAVVLEMYEHLVEDRTTEPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAWGVELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMMITGRSIRETLPFPLAKPR

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1105 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

121.05 kDa

MTVTKPRSVQSRHISRYDWVPAAAGWAVGVIATLSLLASISPLVRWIIKVPREFINSYLFNFPDTSFAWSFVLALLAAALAARKRIAWLLLLTNVVLAAFLNAADIAAGGNTAAQNFGENLGFEVHVVAIVVLVLGYRQFWTKVRRGALFKAAAVLVAGGAIGILVSWGLVDLFPGSLAPHDRLPYVANRVIGFALADPDLFTGRPHVFLNAMFGLFGALALIAATIVLFQSQRADNALTGEDESAIRGLLELYGNSDSLGYFATRRDKSVIFASSGRAAITYRVEIGVCLASGDPVGDPRSWQQAIDAWLRLCQTYGWSPGVMGASSQGAKAYREAGLNALELGDEAILVPADFTLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISGAEMEQTIDRADGWRDTESERGFSMALGRLGDPADTDCLLVEALDPDDLVVAMLSLVPWGTSGVSLDLMRRSPQSPNGTIELMVSELALRAEGLGISRISLNFAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQIETLYRSNQKYQPQWVPRYACYEDARVIPKVGVASVIAEGFLVLPFSRRNKVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQSAIADGDDPQRRLPEQVRVRLNKLKKLRSSGIDAYPVGEPPTHTVAQAMDADDQASVSVSGRILRVRNYGGVLFAHLRDWSGEIQVLLDNSRLGQGRAADFNAAIDLGDLVEMTGQMGSSKTGTRSLIVRRWRLIGKCLRPLPNKWNGLTDPEARVRTRYVDLAVNAESRTLITARSAVLRSVRETLSAKGFIEVETPILQQVHGGATARPFITHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYRVWIDSCRELIQNAAQAANGAPVAMRPAGGGRLEPVGISGVWAVKTVHDAVSEALGEQIDADTDLATLRRLADAARIPYRAQWDAGAVVLELYEHLVESRTEQPTFYLDFPTSVSPLTRPHRSKPGIAERWDLVAWGVELGTAYSELTDPVEQRLRLEEQSLLAAGGDPEAMQLDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPH

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1105 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

121.087 kDa

MTVTKPRSVQGRHISRYDWVPAAAGWAVGVIATLSLLASISPLVRWIIKVPREFINSYLFNFPDTSFAWSFVLALLAAALAARKRIAWLLLLTNVVLAAFLNAADIAAGGNTAAQNFGENLGFAVHVVAIVVLVLGYRQFWAKVRRGALFKAAAVLVAGGAIGILVSWGLVELFPGSLAPHDRLPYVANRVIGFALADPDLFTGRPHVFLNAMFGLFGALALIAATIVLFQSQRADNALTGEDESAIRGLLELYGNSDSLGYFATRRDKSVIFASSGRAAITYRVEIGVCLASGDPVGDPRSWPQAIDAWLRLCQTYGWSPGVMGASSQGAKAYREAGLNALELGDEAILVPADFTLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISDAEMEQTIDRADGWRDTESERGFSMALGRLGDPADTDCLLVEALDPDDLVVAMLSLVPWGTSGVSLDLMRRSPQSPNGTIELMVSELALRAEGLGISRISLNFAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQIETLYRSNQKYQPQWVPRYACYEDARVIPKVGVASVIAEGFLVLPFSRRNKVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQSAIADGDDPQRRLPEQVRVRLNKLKKLRSSGIDAYPVGEPPTHTVAQAMDADDQASVSVSGRILRVRNYGGVLFAHLRDWSGEIQVLLDNSRLEQGRAADFNAAIDLGDLVEMTGQMGSSKTGTRSLIVRRWRLIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNAESRALITARSAVLRSVRETLSAKGFIEVETPILQQVHGGATARPFITHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYRVWIDSCRELIQNAAQAANGAPVAMRPAGGGRLEPVDISGVWAVKTVHDAVSEALGEQIDADTDLATLRRLADAARIPYRAQWDAGAVVLELYEHLVESRTEQPTFYLDFPTSVSPLTRPHRSKPGIAERWDLVAWGVELGTAYSELTDPVEQRLRLEEQSLLAAGGDPEAMQLDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPH

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1104 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

121.729 kDa

MESPPENPRQARRFRKGRFSQVPHISGLILGVFSVLVFLWSISPVLRHILRVPREYIDSYYFDAPDTSLSWALVVALLAAALASRKRIAWWLLTIYLALITLTNIASTIVDKNPNNAVAAVVLLVVIGILIAARPEFYTRVRRGAGWKALGVLIGGMAVATVIGWGLVELFPGDLPQNQRFLWALNRVTAAASVDNEVFDGHPRVFVNTVLGLLGAIALLAAVMTLFRAQRSNNALTGNDESAIRGLIQNFGADDSLAYFATRRDKAVIFAPSGKAAITYRVEIGVCLASGDPIGDPEAWPHAIEAWQDLASQYGWATAVMGASETGATAYKKAGLSVLQLGDEAILRTREFNLNGRDMRPVRQAVTRVRRHGVTVRMRRHRDIPPEDMAAVIIRADDWRDTDTERGFSMALGRLGDHLDGDCLLVEAVMGEGTEDESVVGMLSLVPWGPNGVSLDLMRRKPTAPNGVVELMVSELATRSDEIGVVRVSLNFAVFRSVFEEGSRIGAGPILRIWRSVLVFFSRWWQLEALYRSNVKYQPDWEPRFLCFEDNRELPRVGFASAIAEGFVVLPSFGRKSSQVVKHTGTHAAVPAALVTSEGLHADGSPPDSAPSFTTNGPRRPEQVRVRMNKLAQLADEGIAAYPVAYPPTHTIAAAAKSPEGTRVRIAGRLLRVRDYGGVVFTDVRDWSGDIQVLVDQDNVGREKLAEFAAEFDLGDLIEVSGTIGRSRKGELSLIAVEWRMNGKCLHPLPDKWKGLSDPETRVRQRYLDIALNPKARELLEARSAVVKSLRDSLGGRGYLEVETPILQQVHGGANAAPFLTHINAYNLDLYLRIAPELYLKRLCVAGMEKVFEIGRVFRNEGVDFKHNPEFTILEAYEAHSDYEGMMRMCRELIQAAAVAAFGREIIMRPGPDGELVEVDISGEWPVKTMHGAVAEKLGVDVSPETSLEDLQKLCDANEIPYQSSWDTGAIAQEMYEHLVEDYTEFPTFYTNFPTSMSPLTRPHRSIPGVAEKWDLVAWGVELGTAYSELTDPVDQRNRLTEQSMLAAGGDPEAMELDEDFLQALEHAMPPTGGLGMGVDRIVMLITGGSIRETLAFPLAKPRQ

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1101 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

120.683 kDa

MTATRLVRAHPESSHRWVPAAAGWIVGVIATLSLLASVSPLVRSIIRVPREFVDDYIFNFPDTSFAWAFVLALLAAALAARKRIAWWILTGYMVAAAVWNVTGLLDGDRWFEDVGEIIGLGFHLAAIASLLLARREFWARVRPGALVKAAVTLVAGLGVGTLIGWGLLELFPGTLARPDRFWYALNRVGAFAGADAGAFSGHPHVLVNALLGLFGAMALMIAAVVLFQSQRADNALTGEDESAIRGLLELYGKNDSLGYFATRRDKAVVFAPNGRAAITYRVEVGVCLASGDPVGDPKAWPQAIEAWLTLCETYGWAPGVMGASATGAQAFRQAGLHALQLGDEAILHPDDFRLSGPEMRAVRQAVTRARRAGVAVRFRRHRELSPDEMAEVIAHADAWRDTEDERGFSMALGRLGDPADADCLLVEAVQNGTQVVAMLSLVPWGSNGVSLDLMRRAPQSPNGTIELMVSELCLQSESIGISRISLNFAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARLVPRVGVASVIAEGFLVLPFSRRHDQPHTGHHIAAPGDLIATGRLHSDGTAPDRIGPVGDGADDDAAPRLPEQVRVRMAKLSALQDRGVDAYPVGSPPSHTIAEAIAAEEGTEVTVSGRVLRARDYGGVLFGQLRDWSAETQVALDNSALLDGTTTDFTRTVDLGDLIEVTGTMGHTRSGSWSVLVTRWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTDARELIKARSAILHAIRETLVGKGFLEVETPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYTVWIDGCRELIQNAAMAANGSHVFFRPREDGVLEPVDISGRWAVKTVHGAVSEALGEHIDVDTDLATLRRLCDKAGIPYLTHWDAGAVVLEMYEHLVEDQTTEPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAWGVELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPR

lysX

Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX

1100 amino acids

Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).

In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.

120.437 kDa

MTPTSLARARPTSSHRWVPAAAGWIVGVIATLSLLASVSPLVRSLIRVPREWVDDYIFNFPDTSFAWAFVLALLAAALAARKRIAWWILVGYMIAAAGWNIAGLAEGRERWFAEVGEVIGLAFHLAAIAFLLLARKEFWARVRRGALLKAAATLVASMAVGTLIGWGLLELFPGSLARSDRFLYALNRVSAFAGADAASFSGHPHVFVNALLGLFGAVALMVTAIVLFQSQRADNALTGEDESAIRGLLELYGKNDSLGYFATRRDKAVVFAPSGRAAITYRVEVGVCLASGDPVGDPRSWPQAIDAWLKLCQAYGWAPGVMGASAAGAQAFREAGLNALQLGDEAILHPEDFRLSGPDMRAVRQAVTRARRAGATVRIRRHRELPADEMAAVIERADAWRDTDDERGFSMALGRLGDPADGDCLLVEAVQADQVVAMLSLVPWGGNGVSLDLMRRSPQSPNGTIELMVSELCMQSEDIGITRISLNFAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYDDARLVPRVGVASVIAEGFLVLPFSRRHEQPHTGHHIAAPGTLVATGLLHSDGTAPDGMGLQADLADDDQPRLPEQVRVRMAKLKALQAQGVDAYPVANPPSHTVAQALAAEDGADVAVAGRVLRSRDYGGVLFAQLRDWSGETQLVLDNSLLADGSTADFTRTIDLGDLIEVTGTMGRSRSGKWSLLVSGWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTDARELIRARSAVLHAIRETLVAKDFLEVETPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYHVWIDGCRELIQNAAQAANGAQVFMRPRADGVLEPVDISGPWTVKTVHGAVSEALGEQIGPDTDLATLRLLCDRAGIPYLTHWDAGAVVLELYEHLVEDQTREPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAWGVELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPR

lysX

Alpha-aminoadipate--LysW ligase LysX

285 amino acids

Catalyzes the ATP-dependent formation of a covalent bond between the amino group of alpha-aminoadipate (AAA) and the gamma-carboxyl group of the C-terminal glutamate residue in LysW.

Belongs to the RimK family. LysX subfamily.

33.107 kDa

MILGVIYDLLRWEEKNLIQEARKLGHTVIPIYTKDFYYFYNNDSNETLGDLDVVIQRNTSHARAVITSTIFENLSYKTINDSSTLIKCENKLYTLSLLSKHGIRVPKTIVAFSKEKALELANKLSYPVVIKPVEGSWGRMVARAIDEDTLRNFLEYQEYTTLQFRYIYLIQEFVKKPDRDIRIFTIGDEAPVGIYRVNSRNWKTNTALGAKAEPLKIDEELQDLALKVKDIIGGFFLGIDVFEDPERGYIINEVNGVPEYKNTVRVNNFNVSEYLIRKIEEWIKK

lysX

Alpha-aminoadipate--LysW ligase LysX

280 amino acids

Catalyzes the ATP-dependent formation of a covalent bond between the amino group of alpha-aminoadipate (AAA) and the gamma-carboxyl group of the C-terminal glutamate residue in LysW.

Belongs to the RimK family. LysX subfamily.

30.718 kDa

MLAILYDRIRPDERMLFERAEALGLPYKKVYVPALPMVLGERPKELEGVTVALERCVSQSRGLAAARYLTALGIPVVNRPEVIEACGDKWATSVALAKAGLPQPKTALATDREEALRLMEAFGYPVVLKPVIGSWGRLLAKVTDRAAAEALLEHKEVLGGFQHQLFYIQEYVEKPGRDIRVFVVGERAIAAIYRRSAHWITNTARGGQAENCPLTEEVARLSVKAAEAVGGGVVAVDLFESERGLLVNEVNHTMEFKNSVHTTGVDIPGEILKYAWSLAS

lysX

Alpha-aminoadipate--LysW ligase LysX

276 amino acids

Catalyzes the ATP-dependent formation of a covalent bond between the amino group of alpha-aminoadipate (AAA) and the gamma-carboxyl group of the C-terminal glutamate residue in LysW.

Belongs to the RimK family. LysX subfamily.

31.712 kDa

MRWEEKDIITEAKKSGFKAIPIFTKDFYSAIGVGENYSELEADVIIQRNTSHARALTTSLIFEGWNYNVVNDATSLFKCGNKLYTLSLLAKHNIKTPRTIVTFSKDKAVDLAKKIGFPAVIKPIEGSWGRMVAKAVDEDILYSFLEYQEYTTSQFRQIYLVQEFVKKPNRDIRIFVMGDEAPVGIYRVNERNWKTNTALGARALPLKIDDELRDLALKVRDIMGGFFLGIDIFEDPERGYLVNEVNGVPEYKNTVRVNNFNVSSYLLNKLREWIKK

lysX

Alpha-aminoadipate--LysW ligase LysX

275 amino acids

Catalyzes the ATP-dependent formation of a covalent bond between the amino group of alpha-aminoadipate (AAA) and the gamma-carboxyl group of the C-terminal glutamate residue in LysW.

Belongs to the RimK family. LysX subfamily.

32.028 kDa

MPRWEEKNLIEEGKKLGYQVATIYSKDFVLFSNDFTIDNDTDLFIQRNVSHNRALITSFLVEQVGYPVINDHTTLIRCENKIFTTYILARHNIPTPKTFIAFDKTNAIEYSKKLGYPVVIKPVEGSWGRMVAKADNLDVLYSYLEYQEFSTQKYKDIYYIQEFVNKPNRDIRIFVIGDETPVGIYRVNENNWRTNTALGAKAYPLKIDEELRELALKVKDIIGGFFLGIDIFEDKDRGYLVDEVNGVPEYKNTVRVNNFNVSKFLLEKAAEWVKK

LysX

Lysozyme X

142 amino acids

Unlikely to play an active role in the humoral immune defense. May have a function in the digestion of bacteria in the food. May be involved in the clearance of bacteria from the larval gut before metamorphosis.

Belongs to the glycosyl hydrolase 22 family.

15.591 kDa

MRALLGICVLALVTPAVLGRTMDRCSLAREMANMGVSRDQLSKWACIAEHESSYRTGVVGPPNTDGSNDYGIFQINDMYWCQPSSGKFSHNGCDVSCNALLTDDIKSSVRCALKVLGQQGWSAWSTWHYCSGYLPPIDDCFV