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lxr4

Gene
lxr4
Protein
L-xylo-3-hexulose reductase
Organism
Hypocrea jecorina (strain QM6a)
Length
304 amino acids
Function
L-xylulose reductase involved in the catabolism of D-galactose through an oxidoreductive pathway. Catalyzes the NADPH-dependent reduction of L-xylo-3-hexulose. Is also active with D-ribulose and L-xylulose, and to a lesser extent with D-xylulose, D-fructose and L- and D-sorbose. In the reverse reaction, shows activity with D-sorbitol and D-mannitol, low activity with xylitol, but no activity with galactitol, ribitol, and L- and D-arabitol.
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
32.296 kDa
Sequence
MARPYEGKLAIVTGASRGIGAAVARRLAAKGSNVLITFTSDSSRDLTRGLVEELSSKHGVHVQSVQTDLAKASTAAPIIVEAARTLFDSYSPPSGGKKFQVDILINNAGVSSNQFLNDPEKGAIDEAEFTRVYAINVLAPLLLTQAVAPHLPADRSGRIVNVSSVSASIGYLGQSVYAGSKGALEVMTRTWARELAERATVNSVNPGPAWGDMYAEAGPTFWRRNQPYVDAAPLMAYDGEEDVLRRAGGEADKFDRLVREQMGGRRPGFADEIAGTVDMLCTEESGWTTGSVVCANGGMRMSIA