Protein
Transcriptional regulator LsrR
Organism
Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
Function
Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI-2, LsrR is inactivated by binding phospho-AI-2, leading to the transcription of the lsr genes (By similarity).
Similarity
Belongs to the SorC transcriptional regulatory family.
Sequence
MSEEELLARIAWFYYHDGLTQGDIGDLLGLSRLKVSRLLEKGRQSGVIRVQINSRYEGCLALEDTLQKHFSLKQVRVLPALANMNLSARLGVGAAHLLMALIEPQQLLAVGFGETTMCALQHLSGFISSQQIRLVTLSGGVGPYMTGIGQLDAACSINIIPAPLRASTAQVAETFRQESSVRDVLLAACAADIAIVGIGAVNQQQQATIMRSGYISGGEQLMFGRKGAVGDILGYFMRADGELVEDMQIHQELIGISMPELKTIPTVIGVAGGEEKAEAIIAALNGQYINGLVTEEQTARVMLNLLR