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lpxH

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Ralstonia solanacearum (strain GMI1000)
Length
268 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
29.768 kDa
Sequence
MSDAPTASALKTPVRVSGPVFFISDLHLSAGMPATAAAFERFVRTRAREARTLVILGDFFEYWVGDEELADPFHRHVAALLAELAQAGTRVLLMHGNRDFLLGKRFLATTQATLLPDPSVLEADGLRIVLAHGDALCTRDAAYMRFRRWTRKRWVQRLFLAMPLRWRLRIAQKMRADSEAGRALSANVAGEPRAAAMMGDVAPEAVDALFKAAGIPLLIHGHTHRPRLHHEPGGERWVLSDWDFDHAQPRGSFLRLQDGVLTAEPVTA

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Ralstonia solanacearum (strain GMI1000)
Length
268 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
29.768 kDa
Sequence
MSDAPTASALKTPVRVSGPVFFISDLHLSAGMPATAAAFERFVRTRAREARTLVILGDFFEYWVGDEELADPFHRHVAALLAELAQAGTRVLLMHGNRDFLLGKRFLATTQATLLPDPSVLEADGLRIVLAHGDALCTRDAAYMRFRRWTRKRWVQRLFLAMPLRWRLRIAQKMRADSEAGRALSANVAGEPRAAAMMGDVAPEAVDALFKAAGIPLLIHGHTHRPRLHHEPGGERWVLSDWDFDHAQPRGSFLRLQDGVLTAEPVTA

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Edwardsiella ictaluri (strain 93-146)
Length
259 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
29.503 kDa
Sequence
MATLFIADLHLSQQEPAITAGFLRFLAEEAPKAEALYILGDFFDYWIGDDDPQPLHRQVAGALRQLSDNGVPCYFICGNRDFLLGKSYAKRCGMTLLPDEQIITLYGQPILLLHGDTLCSDDRDYQRYRRRVHNPLLQWLFRRLPLRLRLKIAVGMRQQSQRSNSAKAMTIMDVNQETVCATLRRHGVQRMIHGHTHRPALHHFSLDDGRCALRAVLGAWHTHGSMIRVDAQGIHLIELPAHPAEDEIITTRLRSANLV

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Length
258 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.292 kDa
Sequence
MNKLALQGPLWLASDLHLGPATPATAEAFLGLLQAAADEASALLLPGDIFDAWIGDDVIRAAPPWLAAVLQGIRAAAGRIPVYLGRGNRDFLIGQELADALGAHLLPEPVLLETDYGRILLTHGDEYCTDDSAYQQFRAMVRNPQWQAQFLAMSIPERLAMAEQARGESQAANQAKSMEIMDVNPASVEAALREADVDVLVHGHTHRPARHVLSVDGRKRERWVLPDWDCDHADPPRGGWLVIDRDGLQCFDLVEDED

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
Length
258 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.292 kDa
Sequence
MNKLALQGPLWLASDLHLGPATPATAEAFLGLLQAAADEASALLLPGDIFDAWIGDDVIRAAPPWLAAVLQGIRAAAGRIPVYLGRGNRDFLIGQELADALGAHLLPEPVLLETDYGRILLTHGDEYCTDDSAYQQFRAMVRNPQWQAQFLAMSIPERLAMAEQARGESQAANQAKSMEIMDVNPASVEAALREADVDVLVHGHTHRPARHVLSVDGRKRERWVLPDWDCDHADPPRGGWLVIDRDGLQCFDLVEDED

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Length
258 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.282 kDa
Sequence
MNKLALQGPLWLASDLHLGPATPATAEAFLGLLQAAADEASALLLPGDIFDAWIGDDVIRAAPPWLAAVLHGIRAAAGRIPVYLGRGNRDFLIGQELADALGAHLLPEPVLLETDYGRILLTHGDEYCTDDSAYQQFRAMVRNPQWQAQFLAKSIPERLAMAEQARGESQAANQAKSMEIMDVNPAAVEAALREADVDVLVHGHTHRPARHVLSVDGRKRERWVLPDWDCDHADPPRGGWLVIDRDGLQCFDLVEDED

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT)
Length
255 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
29.672 kDa
Sequence
MSTLFIGDIHLSVEYPEITKNFFRFLQTEATQAESLYILGDLFDKWIGDDDPHPFYREVAAELFALKKKGIPCYFIHGNRDFLIGQAFADESGMILLPECKVIQLYDYNICILHGDTLCTKDTEYQIFRKIAHHRFIQRLFLCLPLSFRFYIAKKLRLQSGEQNKKKGEEIMDVDPQSVLDLMACHDVDWIIHGHTHRPAIHNIEMIVTPLLSSKKIARRAVLSAWHNEGSMIKVTFDAIELIFFPFRVSDFEKI

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Aeromonas salmonicida (strain A449)
Length
254 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.657 kDa
Sequence
MSTLFISDIHLCSDRPDMTAALVRFLERDAPGADALYVLGDLFEFWIGDDDPNPLHHAIADAFAALRQRGVSIYFIHGNRDFLLGRQFAKRSGMTLLADPCVIDLYGERVLLSHGDLLCTLDLGYQKLRRITQLKWLRWLFLRLPLTRRLAIACKMRGQSQMENVQKSQTIMDVTPAAVDALLRQHGCQLLIHGHTHRPAIHDFTLDGQPARRIVLGDWFEQGSVLVCSPGEQRLEQRTLPSLNPAGAHESDNL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Laribacter hongkongensis (strain HLHK9)
Length
253 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.744 kDa
Sequence
MATLILADLHLSADTPAFNDAFLRLLNAAAGQIDALYLLGDIFEVWLGDDDPAPFPRSIISALHRFATSTPVYVMHGNRDFLLGPRFARESGATLLADPTLVELHGHRYLLSHGDLLCTDDIAYQRFRRTIRQPWRQWLLRHLPLALRQRIGQRLRQQSRTAKNDKPLYIMDASTEEVGRWLLEHAGSTLIHGHTHRPGHHRHVLTNGTLAERWVLPDWRPGQTGGLWIDQNGVHPAPDPLYDLQTHTGNQTR

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Xylella fastidiosa (strain M23)
Length
250 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.587 kDa
Sequence
MTTLIISDLHLDPLRPVVTELFLRFLREQVSGADALYILGDLFEIWIGDDMPSEVADMVVAALRTHADAGTPLYFMPGNRDFLVGADYAARAGFRILPDPCVVDLYGEPTLLLHGDLLCTDDIAYQAFRAQTRDPEFIAQFLTQTLSARLAFAQQARLASHAHQSGLKQENDSTQFEKITDVVPADVAAMFACYGVNRMIHGHTHRPALHMLQVAECACTRVVLGDWYQQGSVLCVDADGLVLEQLLLPG

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Xylella fastidiosa (strain 9a5c)
Length
250 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.612 kDa
Sequence
MTTLIISDLHLDPLRPVVTELFLRFLREQVSGADAIYILGDLFEVWIGDDMPSEVADRVAAALRTHADAGTPLYFMPGNRDFLVGADYAARAGFRILPDPCVVDLYGEPTVLLHGDLLCTDDIAYQAFRAQTRDPEFIAQFLTQTLSARLAFAQQARLASHAHQSGLKQEDDCTQFEKVTDVVPADVAAMFACYGVNRMIHGHTHRPALHTLQVAERTCTRVVLGDWYQQGSVLCVDADGLVLEQLLLPG

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Xylella fastidiosa (strain M12)
Length
250 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.587 kDa
Sequence
MTTLIISDLHLDPLRPVVTELFLRFLREQVSGADALYILGDLFEVWIGDDMPSEVADMVAAALRTYADAGTPLYFMPGNRDFLVGADYAARAGFRILPDPCVVDLYGEPTLLLHGDLLCTDDIAYQAFRAQTRDPEFIAQFLTQTLSARLAFSQQARLASHAHQSGLKQENDSTQFEKITDVVPADVAAMFACYGVNRMIHGHTHRPALHMLQVAECACTRVVLGDWYQQGSVLCVDADGLVLEQLLLPG

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Xylella fastidiosa (strain Temecula1 / ATCC 700964)
Length
250 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.587 kDa
Sequence
MTTLIISDLHLDPLRPVVTELFLRFLREQVSGADALYILGDLFEIWIGDDMPSEVADMVVAALRTHADAGTPLYFMPGNRDFLVGADYAARAGFRILPDPCVVDLYGEPTLLLHGDLLCTDDIAYQAFRAQTRDPEFIAQFLTQTLSARLAFAQQARLASHAHQSGLKQENDSTQFEKITDVVPADVAAMFACYGVNRMIHGHTHRPALHMLQVAECACTRVVLGDWYQQGSVLCVDADGLVLEQLLLPG

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / NCIMB 11848 / C-107)
Length
250 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.949 kDa
Sequence
MATFFISDLHLGTGKTEIQLRAIEFLSQEAPYGDALYILGDLFDYWIGDDAPTAEGLAIITALRRLADVGVTLHFLSGNRDFLVGQVFSQASGCQILSDPAIIDLYGVPTLLMHGDTLCTDDVAYQRARARLRRPAILRTYLALPKSWRRAVAQRLRRQSQAHVQHQPLTIMDVNQTAVETALRIHGVKQLIHGHTHRPAVHHFTVDGHPRQRIVLGDWDRGKSALSCTPEGFHFSDSRILEPRFGNLQG

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Length
250 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.383 kDa
Sequence
MILLISDLHLEEERPDITRAFLELLGGRARAAEALYILGDFFEVWIGDDAMTPYQLSICQALRELSDSGTQIFLMHGNRDFMLGKAFCKAAGATLLKDPSVVDFYGEPVLLMHGDSLCTRDEAYMRMRRYLRNPLSLWILRHLPLGTRRKLARKLRNESRAQTRMKANDIVDVTPDQVPQVMQEHGVRTLVHGHTHRPAIHKLQIGEQAAKRIVLGDWDRQGWALQVDEQGFQLAAFDFVPTQLALPGSP

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Length
250 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.383 kDa
Sequence
MILLISDLHLEEERPDITRAFLELLGGRARAAEALYILGDFFEVWIGDDAMTPYQLSICQALRELSDSGTQIFLMHGNRDFMLGKAFCKAAGATLLKDPSVVDFYGEPVLLMHGDSLCTRDEAYMRMRRYLRNPLSLWILRHLPLGTRRKLARKLRNESRAQTRMKANDIVDVTPDQVPQVMQEHGVRTLVHGHTHRPAIHKLQIGEQAAKRIVLGDWDRQGWALQVDEQGFQLAAFDFVPTQLALPGSP

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Blochmannia pennsylvanicus (strain BPEN)
Length
250 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
29.061 kDa
Sequence
MSILFISDVHLSTKSPYITDGFLRFLSYRAMRAKALYILGDLFETWLGDDDYNLLHINIAKALKALNQRRISCYFIHGNHDFLLGQRYARACGMTLLSSNQVLKLASGKKIIILHGDILCANDNSYQLFRKYLRHIIVQRLFLSLPLSIRSRIFSAIRSCCVQHTKYKSKKKLNINLKIATDMLIQNNADIMIHGHTHQPAIHKIYRSKKNVFRIIVLGCWNKYGSMIEVNEKNNDILFTEFPLYEITKY

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas fluorescens (strain SBW25)
Length
249 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.142 kDa
Sequence
MILLISDLHLEEERPDITRAFLDLLHHRARGAQALYILGDFFEAWIGDDGMTPFQRSICAALRELSDSGTPIFIMHGNRDFLIGKAFCKAAGATLLKDPSVVQLHGEPVLLMHGDSLCTRDVGYMKLRRILRNPIVLFILRHLPLRTRHKLARKLRSESRAQTRMKANDIVDVTPEEVPRVMQQFGVRTLVHGHTHRPAIHKLQIGDQAAKRIVLGDWDKQGWALQVDEQGFQLAAFDFVNPQLALPGA

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas fluorescens (strain SBW25)
Length
249 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.142 kDa
Sequence
MILLISDLHLEEERPDITRAFLDLLHHRARGAQALYILGDFFEAWIGDDGMTPFQRSICAALRELSDSGTPIFIMHGNRDFLIGKAFCKAAGATLLKDPSVVQLHGEPVLLMHGDSLCTRDVGYMKLRRILRNPIVLFILRHLPLRTRHKLARKLRSESRAQTRMKANDIVDVTPEEVPRVMQQFGVRTLVHGHTHRPAIHKLQIGDQAAKRIVLGDWDKQGWALQVDEQGFQLAAFDFVNPQLALPGA

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Wigglesworthia glossinidia brevipalpis
Length
248 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
29.227 kDa
Sequence
MSTLFVSDVHLSEKNPKLTDLFFYFLKNKAILSRSLYILGDLFETWVGDDNITYISKELANITNYLADNGTSCYFIKGNRDFLIGKSYFKSSKITLLPYKKIININKQSIIILHGDTLCLNDKNYQKFKKLVNQDWLQKFFLKLPLCARIKISNLIINKRKKLNLKRMNYLTKINKEYIKKIMEQTNTNIMIHGHIHMPKVHVLPNRKYRIVLGMWNKSGSILEINKKLSLIKFSKLYCSYTSYPLKY

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6)
Length
248 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.269 kDa
Sequence
MILLISDLHLEQDRPDITRAFLDLLAGRAREAEALYILGDFFEVWIGDDAMSPFQLSICKALRALSDSGTRIFLMHGNRDFMIGKGFCKAAGCTLLSDPSVVQLNGERVLLMHGDSLCTRDEGYIRMRRYLRHPLTLFILRHLPLGTRHKLARKLRNESRAQTRMKANDIVDVTPDEVPRIMQQFGVRTLVHGHTHRPAIHKLQIGDQAARRIVLGDWDRQGWVLQVDEQGFSLNSFDFVPETTALLN

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas fluorescens (strain Pf0-1)
Length
248 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.165 kDa
Sequence
MILLISDLHLEEERPDITRAFLDLLAGRARSASALYILGDFFEAWIGDDAMTPFQRSICQALRELSDSGTAIFLMHGNRDFMLGKAFCKQAGCTLLKDPSVVQFYGEPVLLMHGDSLCTRDESYMKLRRYLRNPLSLFILRNLPLRTRHKLARKLRSESRAQTRMKANDIVDVTPEEIPRIMQEYGVKTLVHGHTHRPAIHKLQIGDQAAKRIVLGDWDRQGWALQVDENGFALAPFDFAPPLALPHG

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Length
248 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.213 kDa
Sequence
MILLISDLHLEQERPDITRAFLALLAGRARTAEALYILGDFFEAWIGDDAMSPFQRSICQALRELSDSGTRIFLMHGNRDFMLGKGFCKAAGCTLLSDPSVVQLNGEPVLLMHGDSLCTRDEGYMRMRRYLRHPLTLFILRHLPLSTRHKLARKLRNESRAQTRMKANDIVDVTPDEVPRIMQQFGVRTLVHGHTHRPAIHKLQIGDQSAKRIVLGDWDRQGWVLQVDEQGMNLGSFDFVPETVALLN

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas syringae pv. syringae (strain B728a)
Length
248 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.296 kDa
Sequence
MILLISDLHLEQERPDITRAFLDLLAGRAREAESLYILGDFFEVWIGDDAMSPFQLSICKALRELSDSGTRIFLMHGNRDFMLGKGFCKAAGCTLLSDPSVVQLNGEPVLLMHGDSLCTRDEGYIRMRRYLRHPLTLFILRHLPLGTRHKLARKLRNESRAQTRMKANDIVDVTPDEVPRIMQQFGVRTLVHGHTHRPAIHKLQIGDQAARRIVLGDWDRQGWVLQVDEQGFNLSSFDFVPETVALLN

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas fluorescens (strain Pf0-1)
Length
248 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.165 kDa
Sequence
MILLISDLHLEEERPDITRAFLDLLAGRARSASALYILGDFFEAWIGDDAMTPFQRSICQALRELSDSGTAIFLMHGNRDFMLGKAFCKQAGCTLLKDPSVVQFYGEPVLLMHGDSLCTRDESYMKLRRYLRNPLSLFILRNLPLRTRHKLARKLRSESRAQTRMKANDIVDVTPEEIPRIMQEYGVKTLVHGHTHRPAIHKLQIGDQAAKRIVLGDWDRQGWALQVDENGFALAPFDFAPPLALPHG

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Length
248 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.213 kDa
Sequence
MILLISDLHLEQERPDITRAFLALLAGRARTAEALYILGDFFEAWIGDDAMSPFQRSICQALRELSDSGTRIFLMHGNRDFMLGKGFCKAAGCTLLSDPSVVQLNGEPVLLMHGDSLCTRDEGYMRMRRYLRHPLTLFILRHLPLSTRHKLARKLRNESRAQTRMKANDIVDVTPDEVPRIMQQFGVRTLVHGHTHRPAIHKLQIGDQSAKRIVLGDWDRQGWVLQVDEQGMNLGSFDFVPETVALLN

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas syringae pv. syringae (strain B728a)
Length
248 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.296 kDa
Sequence
MILLISDLHLEQERPDITRAFLDLLAGRAREAESLYILGDFFEVWIGDDAMSPFQLSICKALRELSDSGTRIFLMHGNRDFMLGKGFCKAAGCTLLSDPSVVQLNGEPVLLMHGDSLCTRDEGYIRMRRYLRHPLTLFILRHLPLGTRHKLARKLRNESRAQTRMKANDIVDVTPDEVPRIMQQFGVRTLVHGHTHRPAIHKLQIGDQAARRIVLGDWDRQGWVLQVDEQGFNLSSFDFVPETVALLN

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Stenotrophomonas maltophilia (strain R551-3)
Length
248 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.577 kDa
Sequence
MTTLFISDLHLDPSRPEITDLFLRFLREQAPTADALYILGDLFEAWIGDDTPSPAADAVADALKVLTDSGVPAYFIRGNRDFLLGEDYARRAGLRILPDPCVIELYGRPVLLQHGDLLCTDDIPYQQFRAQTRDPAFQAQFLSQPLAARIAFAQKARETSQARQSEMKQGDRATFENVTDVAPAEVDATFVRHGVDTMIHGHTHRPAIHALQAGGRACTRIVLGDWYEQGSVLRVDANGWTLDTLSRE

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Stenotrophomonas maltophilia (strain K279a)
Length
248 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.466 kDa
Sequence
MTTLFISDLHLDPSRPEITDLFLRFLREQAPGADALYILGDLFEAWIGDDTPSPAADAVADALKVLSDSGVPVYFIRGNRDFLLGEDYARRAGLRILPDPCMIDLYGRPVLLQHGDLLCTDDIPYQQFRAQTRDPAFQAQFLSQPLAARIAFAQKAREASQARQSEMKQGDRAQFETVTDVAPSEVDATFARHGVDTMIHGHTHRPAIHSLQAGGRACTRIVLGDWYEQGSVLRVDAGGWSLDTLARE

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Xanthomonas axonopodis pv. citri (strain 306)
Length
247 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.976 kDa
Sequence
MTTLFISDLHLDPARPAITELFLEFLRTQVPGSDALYILGDLFEAWIGDDTPSTAADAVAVALHAVADSGVPVFFMAGNRDFLVGETYAQRAGFRILPDPTVIDLYGHTTLLMHGDLLCTDDTAYQAFRAQTRDPVFQAQFLAQPLAARVAFAQQARAASQARHAELKQGDQSRFETVTDVSPAEVEATFVRYGLDRLIHGHTHRPAIHTLQAGGHTCTRIVLGDWYEQGSVLRVDADGASLEQLAL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Xanthomonas campestris pv. campestris (strain 8004)
Length
247 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.864 kDa
Sequence
MTTLFISDLHLDPARPAITELFLDFLRTQVPGSDALYILGDLFEAWIGDDTPSTAADAVAEALHAVATTGVPVFFMPGNRDFLVGAAYAQRAGFRILPDPTVIDLYGQPTLLMHGDLLCTDDTAYQAFRAQTRDPAFQAQFLSQPLAARVAFAQQARAASHARQSELKQGDQAQFETVTDVAPAEVDATFVRYGLDRIIHGHTHRPAIHTVQAGGRTCTRVVLGDWYEQGSVLRVDADGLALEQLAL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Xanthomonas campestris pv. campestris (strain B100)
Length
247 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.876 kDa
Sequence
MTTLFISDLHLDPARPAITELFLDFLRTQVPGSDALYILGDLFEAWIGDDTPSTAADAVAEALHAVATTGVPVFFMPGNRDFLVGAAYAQRAGFRILPDPTVIDLYGQPTLLMHGDLLCTDDTAYQAFRAQTRDPAFQAQFLSQPLAARVAFAQQARAASHARQSELKQGDQAQFETVTDVAPAEVDATFVRYGLDRIIHGHTHRPAIHIVQAGGRTCTRVVLGDWYEQGSVLRVDADGLALEQLAL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Length
247 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.864 kDa
Sequence
MTTLFISDLHLDPARPAITELFLDFLRTQVPGSDALYILGDLFEAWIGDDTPSTAADAVAEALHAVATTGVPVFFMPGNRDFLVGAAYAQRAGFRILPDPTVIDLYGQPTLLMHGDLLCTDDTAYQAFRAQTRDPAFQAQFLSQPLAARVAFAQQARAASHARQSELKQGDQAQFETVTDVAPAEVDATFVRYGLDRIIHGHTHRPAIHTVQAGGRTCTRVVLGDWYEQGSVLRVDADGLALEQLAL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Xanthomonas oryzae pv. oryzae (strain MAFF 311018)
Length
247 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.954 kDa
Sequence
MTTLFISDLHLDPARPAITELFLDFLRTQVRGSDALYILGDLFEAWIGDDTPSTAADAVAVALHAVADAGVPVFFMAGNRDFLVGETYAQRAGFRILPDPTVIDLYGHTTLLMHGDLLCTDDTAYQAFRAQTRDPVFQAQFLAQPLAARVAFAQQARAASQARHAELKQGDQSNVETVTDVSPAEVEATFVRYGLDRLIHGHTHRPAIHTVQAGGNTCTRIVLGDWYEQGSVLRLDADGVSLEQFAL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Xanthomonas oryzae pv. oryzae (strain PXO99A)
Length
247 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.954 kDa
Sequence
MTTLFISDLHLDPARPAITELFLDFLRTQVRGSDALYILGDLFEAWIGDDTPSTAADAVAVALHAVADAGVPVFFMAGNRDFLVGETYAQRAGFRILPDPTVIDLYGHTTLLMHGDLLCTDDTAYQAFRAQTRDPVFQAQFLAQPLAARVAFAQQARAASQARHAELKQGDQSNVETVTDVSPAEVEATFVRYGLDRLIHGHTHRPAIHTVQAGGNTCTRIVLGDWYEQGSVLRLDADGVSLEQFAL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)
Length
247 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.954 kDa
Sequence
MTTLFISDLHLDPARPAITELFLDFLRTQVRGSDALYILGDLFEAWIGDDTPSTAADAVAVALHAVADAGVPVFFMAGNRDFLVGETYAQRAGFRILPDPTVIDLYGHTTLLMHGDLLCTDDTAYQAFRAQTRDPVFQAQFLAQPLAARVAFAQQARAASQARHAELKQGDQSNVETVTDVSPAEVEATFVRYGLDRLIHGHTHRPAIHTVQAGGNTCTRIVLGDWYEQGSVLRLDADGVSLEQFAL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Blochmannia floridanus
Length
247 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.677 kDa
Sequence
MSILFIADVHLCNTKPKIIHGFLNFLYNHAMQAQALYILGDLFEVWLGDDEKNIMHMTIAKGLQSLHKKKVPCYFIRGNHDFLLGPKYANLCDMILLPDSQVLKLPSGKNVVILHGDTLCIDDKSYQRLRNFLHCQILQKIFLSLPLSMRLYIFNCARTFCIKYKKYKLKQNLHIKLQTVIDMLIKNQSKILIHGHTHQPAIHNIQISENISFKRIVLGQWNKYGSVATINEKNDDINLIHFPLNKQ

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Length
246 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.39 kDa
Sequence
MHTLFISDLHLSPKHPDITASFIQFMREEAIKADALYVLGDLFDFWIGDDDPTTFAEQIKSEFRQLTQQGVPCYFTKGNRDFLVGKRFAQQTGVQLLPDEAVIDLYGQKAVVLHGDTLCTQDTRYLEFRAKVHQPWLQRLFGLLPFALKQKLVRKIQSDIRDDKQHKSMMIMDVTPSEVIAVMHRYNVDLMIHGHTHRPAIHSIQTDDQTLKTRIVLGDWYSQSSILVYSKLTGYSLLSRPLINIE

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Vibrio cholerae serotype O1 (strain M66-2)
Length
246 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.39 kDa
Sequence
MHTLFISDLHLSPKHPDITASFIQFMREEAIKADALYVLGDLFDFWIGDDDPTTFAEQIKSEFRQLTQQGVPCYFTKGNRDFLVGKRFAQQTGVQLLPDEAVIDLYGQKAVVLHGDTLCTQDTRYLEFRAKVHQPWLQRLFGLLPFALKQKLVRKIQSDIRDDKQHKSMMIMDVTPSEVIAVMHRYNVDLMIHGHTHRPAIHSIQTDDQTLKTRIVLGDWYSQSSILVYSKLTGYSLLSRPLINIE

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Tolumonas auensis (strain DSM 9187 / TA4)
Length
246 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.581 kDa
Sequence
MTKLFIADLHLSESRPDLIQAFIHFLETEARTADELYILGDLFEFWIGDDEQSPLQQQITHALRTLANHGCQLFYSHGNRDFMIGKRFAQECGMTLLPPVYPCELAGEKALLLHGDQLCTDDEAYQRFRRITSWPWLQWIFLHLPLSRRVKIAQQIRQGSHKGKQQKSRSIMDVTPQSVITCFEQHKATLMIHGHTHRPQIHDVTLSSNQPARRIVLGDWDTDLWYLKIDDRDINLISQPINTAKN

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)
Length
246 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.705 kDa
Sequence
MTTLLISDLHLHTGQPDITRGFLDYLERDARHADTLYLLGDIFEAWIGDDYLGDLERQVIEALRRLSDAGTQLYFMHGNRDFLVGEDFAAAAGATLLDDPCLATLGRQTVLLMHGDSLCTGDEEYMKFRAMARDPEWQAQILALPIEQRLELAKSLRMQSSDANTQKADAIMDVTPAEVEAIMREHGVSTLIHGHTHRPAVHEFTLDGQPAQRIVLGDWRPGRGWEVRVEDDAPPRLREFAFQARA

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Photobacterium profundum (strain SS9)
Length
245 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.354 kDa
Sequence
MTTLFIADLHLSAERTDITDCFLHFMQQEARNIDALYVLGDLFEMWIGDDDDSPFLQQIKHAFKQLTDSGVPCYFIYGNRDFLIGSRFCQETGMTLLPEHTVIDLYGTPTLILHGDTLCIEDEDYLRYRKRVHNRFIQWLFFCLPLTYRQKVGDKIRSGSSKNNKEKTTSIMDVTPNEVVRLMAEQNVIDMIHGHTHRPDVHHIEVNGKAAIRTVLGDWYHHGSVLVCTPDGCKLETRDFSEKNQ

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Psychromonas ingrahamii (strain 37)
Length
245 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.933 kDa
Sequence
MRTLFIADLHLSEKHPQISHAFFEFLQNETENVDALYILGDLFEVWIGDDERTLLMNEVALKLSEYALKNNILLYYIHGNRDFMIGKKYAKQSSMQLLPEHCEINLYGKKILILHGDTLCLADKNYQKMRTLLHNPLIQLVFNLLPLFLRKKIGWKIRHASQSKKVYKNREVMDVTKDEVVRLMEKHHVQTLIHGHTHRVACHEMLVKGQAAQRYDVGDWRHNLSYVEVQKDKINLVIRPINFYN

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Psychromonas ingrahamii (strain 37)
Length
245 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.933 kDa
Sequence
MRTLFIADLHLSEKHPQISHAFFEFLQNETENVDALYILGDLFEVWIGDDERTLLMNEVALKLSEYALKNNILLYYIHGNRDFMIGKKYAKQSSMQLLPEHCEINLYGKKILILHGDTLCLADKNYQKMRTLLHNPLIQLVFNLLPLFLRKKIGWKIRHASQSKKVYKNREVMDVTKDEVVRLMEKHHVQTLIHGHTHRVACHEMLVKGQAAQRYDVGDWRHNLSYVEVQKDKINLVIRPINFYN

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Aromatoleum aromaticum (strain EbN1)
Length
245 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.602 kDa
Sequence
MSALFISDLHLCEQRPVTLRAFFAFLQGPARSVQALYILGDLFEYWAGDDDATPLDNAVSDALAALAETGTSLFFLPGNRDFLLGESFARRARLRILPDPTLIDFDNEGVLLSHGDILCTDDEHYQSFRRLVRDPAWQLAFLERPLAQRKQVIEGLRFQSETAKQEKASDIMDVNAFAVETLLREHGYPTLIHGHTHRPAHHVHVVDGRSCERWVLADWHDDAPYLRWDGAGPPVALRFGAKLGT

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Vibrio tasmaniensis (strain LGP32)
Length
244 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.304 kDa
Sequence
MKTYFISDLHLAPSRQDITDCFLTFMKNEALEADALYVLGDLFEFWIGDDDTSEFANSIRQTFIDLVNTGVPCYFTQGNRDFLVGKKFAKQTGVQLLDEVSTIDIYGQKAVVLHGDTLCTEDIKYLAFREKVHQPWLQWVFNRIPFFIKKKIVSKVQSDIKDDKQTKSLDIMDVTQQEVENVMKQHNVDLMIHGHTHRPNIHSFSANNCTKTRIVLGDWYTQGSVLVFTPQSFELQNREFSNRF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)
Length
244 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.813 kDa
Sequence
MTTLFISDLHLEESRPDITGAFLTFLRDKALGVERLYILGDFFEAWIGDDERTPLQEQVAAALREVRDTGTDIYLMHGNRDFLIGEDFCARAGAILLDDPTVVDLYGTPALLMHGDSLCTADVEYQKFRANMRNPQTVKMLLSRPLKDRQLMARQLREISMAKNQGKAETIMDVTPEEVVKELEAHNVQLMIHGHTHRPAIHELEANGRPARRIVLGDWDENVWWLEASKNQPVALRHQPLADF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Hahella chejuensis (strain KCTC 2396)
Length
244 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.659 kDa
Sequence
MPTLFISDLHLEIEKPDLTRFFFNFLDKVAPNAEALYILGDFFEVWVGDDEQSPLQVEVAQRLHKLAEAGTHIHLMHGNRDFLIGETYAKQCGATLLAEPHALDLYGVPSLLMHGDSLCTLDAAYQKARATFRNPAFQSQFLSRPLDQRQLTARQMRQISMAKNQGKAEVIMDVAPDEVINTFNTYGIELLIHGHTHRPDTHRYNLPQGEVKRIVLGDWGEETWYGRADADGFQLLNLKAEDIA

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Vibrio vulnificus (strain CMCP6)
Length
243 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.461 kDa
Sequence
MTTLFISDLHLTPSRTDITECFVQFMRNEAVNAEALYVLGDLFEFWIGDEDCTPFAERIRNEFKALTTSGVPVYFIQGNRDFLLGQRFCRETGITLLDDVCTIDLYGEKVVILHGDTLCIDDLKYQEFRKTVHQRWLQWIFKRIPWFIKKRIVAKVQSGVRDDKQHKSLEIMDVNQQEVAQVMSQFCVKLMIHGHTHRPNIHHFEHDNLPLTRIVLGDWYSQGSVLKVTADGYSLEQRPFFTE

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Vibrio vulnificus (strain YJ016)
Length
243 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.402 kDa
Sequence
MTTLFISDLHLTPSRTDITECFVQFMRNEAVNAEALYVLGDLFEFWIGDEDCTPFAERIRNEFKALTTSGVPVYFIQGNRDFLLGQRFCRETGITLLDDVCTIDLYGEKVVILHGDTLCIDDLKYQEFRKTVHQPWLQWIFKRIPWFIKKRIVAKVQSGVRDDKQHKSLEIMDVNQQEVAQVMSQFCVKLMIHGHTHRPNIHHFEHDNLPLTRIVLGDWYSQGSVLKVTADGYSLEQRPFFTE

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Coxiella burnetii (strain CbuG_Q212)
Length
243 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.286 kDa
Sequence
MRHTLFISDLHLEEETPSITAHFLYFLKHQAPKADAIYILGDFFEAWIGDDNQTPFNRKIIESLQTLARTKPTYFMRGNRDFLIGQRFAAMTGVSLLEDPSVIQLYNKPVLLMHGDSLCTLDHKHQAYRRKIMKPWVQKLMLSLPLSLRRKLAKKFREQSRRHNRTLSYEIKDVTPEEVNRVMKEQNVELLIHGHTHRPAIHDLTINGNPTKRIVLGAWHHGGSVLHYAQDGSFELQAFKIDL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Coxiella burnetii (strain Dugway 5J108-111)
Length
243 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.233 kDa
Sequence
MRHTLFISDLHLEEETPSITAHFLYFLKHQAPKADAIYILGDFFEAWIGDDNQTPFNRKIIESLQTLARTKPTYFMRGNRDFLIGQRFAAMTGVSLLEDPSVIQLYNKPVLLMHGDSLCTLDHKHQAYRRKIMKPWVQKLMLSLPLSLRRKLAKKFREQSRRHNRTLSYGIKDVTPEEVNRVMKEQNVELLIHGHTHRPAIHDLTINGNPTKRIVLGAWHHGGSVLRYAQDGSFELQAFKIDL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Coxiella burnetii (strain RSA 331 / Henzerling II)
Length
243 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.304 kDa
Sequence
MRHTLFISDLHLEEKTPSITAHFLYFLKHQAPKADAIYILGDFFEAWIGDDNQTPFNRKIIESLQTLARTKPTYFMRGNRDFLIGQRFAAMTGVSLLEDPSVIQLYNKPVLLMHGDSLCTLDHKHQAYRRKIMKPWVQKLMLSLPLSLRRKLAKKFREQSRRHNRTLSYEIKDVTPEEVNRVMKEQNVELLIHGHTHRPAIHDLTINGNPTKRIVLGAWHHGGSVLRYAQDGSFELQAFKIDL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Length
243 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.304 kDa
Sequence
MRHTLFISDLHLEEKTPSITAHFLYFLKHQAPKADAIYILGDFFEAWIGDDNQTPFNRKIIESLQTLARTKPTYFMRGNRDFLIGQRFAAMTGVSLLEDPSVIQLYNKPVLLMHGDSLCTLDHKHQAYRRKIMKPWVQKLMLSLPLSLRRKLAKKFREQSRRHNRTLSYEIKDVTPEEVNRVMKEQNVELLIHGHTHRPAIHDLTINGNPTKRIVLGAWHHGGSVLRYAQDGSFELQAFKIDL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Length
242 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.031 kDa
Sequence
MHTLFISDLHLSPKHPDITASFIQFMREEAIKADALYVLGDLFDFWIGDDDPTTFAEQIKSEFRQLTQQGVPCYFTKGNRDFLVGKRFAQQTGVQLLPDEAVIDLYGQKAVVLHGDTLCTQDTRYLEFRAKVHQPWLQRLFGLLPFALKQKLVRKIQSDIRDDKQHKSMMIMDVTPSEVIAVMHRYNVDLMIHGHTHRPAIHSIQTDDQTLKTRIVLGDWYSQSSILVYSKQLATHYCRDHS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Length
242 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.051 kDa
Sequence
MTTLFISDLHLTPSRPDITECFITFMRTEAKNAEALYVLGDLFEFWVGDDDKTPFANQIRTEFKALTDQGVPVFFIQGNRDFLLGERFCKETGITLLDDVCTIDLYGTKAVILHGDTLCIDDVEYQKFRKTVHQPWLQWIFKRIPWYLKKKIVSKVQSDIRDDKQMKSLDIMDVNQSEVEKVMSQNCVNLMIHGHTHRPNTHFFDANGAKNTRIVLGDWYTQGSVLQVNSDGFELQNRPFNT

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas mendocina (strain ymp)
Length
242 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.681 kDa
Sequence
MILLISDLHLEEKRPDITRAFLHFLATRARQAEALYILGDFFEVWIGDDGMTPFQHEIAGALRELSDSGTRIYLMHGNRDFLIGKRFCREAGCTLLGDPHRVQMNGEPVLLMHGDSLCTLDVGYMKLRRWLRNPLSLLILRNLPLATRQKLARKLRNESRAQTRMKASEIVDVTPEEVVRVMGEYDVRTLIHGHTHRPAVHELEVNGQPARRIVLGDWDRQGWALQVDGEGFNQAPFELTPA

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas mendocina (strain ymp)
Length
242 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.681 kDa
Sequence
MILLISDLHLEEKRPDITRAFLHFLATRARQAEALYILGDFFEVWIGDDGMTPFQHEIAGALRELSDSGTRIYLMHGNRDFLIGKRFCREAGCTLLGDPHRVQMNGEPVLLMHGDSLCTLDVGYMKLRRWLRNPLSLLILRNLPLATRQKLARKLRNESRAQTRMKASEIVDVTPEEVVRVMGEYDVRTLIHGHTHRPAVHELEVNGQPARRIVLGDWDRQGWALQVDGEGFNQAPFELTPA

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shewanella loihica (strain ATCC BAA-1088 / PV-4)
Length
242 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.83 kDa
Sequence
MNYTLFVGDLHLSADRPDILNAFHQFLDQDASHCDALYILGDLFEVWVGDDIAEPFALELAERLKRFSTHTPIYFIHGNRDFLLGKEYAKRSGMTLLPEIYSIDLYGEPSVLLHGDSLCTLDKAYQRFRRFRNMAWAKFIYNHLPKSKRIAIADKLRSKSKQSNQIKSYSIMDVEQSAVEQLMAETGAKRMIHGHTHRPDIHRLANDTQRIVVGDWYEQGSVLKISPKEVNLQSLPFGETEA

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)
Length
241 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.299 kDa
Sequence
MSTLFISDIHLCAQRPDMTAALVRFLAHDAPGADALYVLGDLFEFWIGDDDPNPLHGEVADAFAALSQQGVPLYFIHGNRDFLLGQAFAKRAGMTLLGDPCVIELYGERVVLSHGDLLCTLDEGYQKFRRITQLKWLRWLFLRLPLARRQAIAHKMRGQSQMENAHKSQTIMDVTPAAVDQMLRQHDCRMMIHGHTHRPAIHDFQLDGAPARRIVLGDWFEQGSVLICRPGEQRLEQHALI

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Aliivibrio fischeri (strain ATCC 700601 / ES114)
Length
241 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.502 kDa
Sequence
MTILFISDLHLSPLRPDITDCFIDFMQNEAIHAEKLYVLGDLFEFWIGDDDNSPFNVSIKNEFKALTEKGVKCYFIQGNRDFLLNKRFCKETGVELLDDHTVIELDGEKVLIMHGDTLCIDDIKYQEFRAKVHKPWLQWVFNRIPLFIRQRIVKNVQDKIKEKKQTKTLCIMDVTQSEVERVMQEEGVQRLIHGHTHRPDTHTFMSNNKEMTRIVLGDWYSQGSILEYSDKIYSLHKKEFK

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Aliivibrio fischeri (strain MJ11)
Length
241 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.482 kDa
Sequence
MTILFISDLHLSPLRPDITDCFIDFMQNEAIHAEKLYVLGDLFEFWIGDDDNSPFNVLVKNEFKALTKKGVKCYFIQGNRDFLLNKRFCKETGVELLDDHTVIDLDGEKVLIMHGDTLCIDDIKYQEFRAKVHKPWLQWVFNRIPLFIRQRIVKNVQDKIKEKKQTKTLCIMDVTQSEVERVMQEEGVQRLIHGHTHRPDTHTFISNDKEMTRIVLGDWYSQGSILEYSDKIYSLHKKEFK

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Aliivibrio salmonicida (strain LFI1238)
Length
241 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.131 kDa
Sequence
MTILFISDLHLCPTRPEITTCFLDFMENEAVHAKELYVLGDLFEFWIGDDDNSSFSSLIKNAFTTLTNQGVHCFFIQGNRDFLLNKRFCKETGITLLADHTVIDVDGKKVLIMHGDTLCIDDVKYQEFRAKVHQPWLQWIFNRIPLFIRQHIVKNVQDKIKEKKQHKTLSIMDVTQSEVERVMHEEGVNLLIHGHTHRPDTHSFTVNDNQMTRIVLGDWYTQGSILTYKDNTFTLLNKSFK

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Azotobacter vinelandii (strain DJ / ATCC BAA-1303)
Length
241 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.785 kDa
Sequence
MTTLLISDLHLDEERPDIARAFLRFLKERASQAEALYILGDFFEAWIGDDAMTSFQRDIAAALREVAERGTRVFLMHGNRDFLVGHSFCRQAGCTLLRDPSRVILNGAPVLLMHGDTLCTRDIAYMRFRRRLRNPVSVWLLRHLPLSKRRQLARKWRDASRMQVRRKATEIVDVTPEEVPRIMAAHGVLTLIHGHTHRPAVHELQVDGRQARRIVLGDWNRQGWVLQVDGSGYHLTPFPID

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)
Length
241 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.124 kDa
Sequence
MRTLFIGDLHLSADRLDITQAFTHFLDTELDDADALYILGDLFEVWVGDDIAAPFALELANKLKQVSLKLPVYFIHGNRDFMLGKQFARAAGMQILPEVTCLNLYGVKTVILHGDSLCTLDKAYQRFRKLRSLALARWLYGCLSKKTRQGIADNIRSKSKSSNKHKSYTIMDVEPNAVNALLARTHAQYMIHGHTHRPAIHQLDNGCKRIVVGDWYQQGSVLSVSPQGIDLQSLPFSPQQD

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shewanella sp. (strain W3-18-1)
Length
241 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.124 kDa
Sequence
MRTLFIGDLHLSADRLDITQAFTHFLDTELDDADALYILGDLFEVWVGDDIAAPFALELANKLKQVSLKLPVYFIHGNRDFMLGKQFARAAGMQILPEVTCLNLYGVKTVILHGDSLCTLDKAYQRFRKLRSLALARWLYGCLSKKTRQGIADNIRSKSKSSNKHKSYTIMDVEPNAVNALLARTHAQYMIHGHTHRPAIHQLDNGCKRIVVGDWYQQGSVLSVSPQGIDLQSLPFSPQQD

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shewanella frigidimarina (strain NCIMB 400)
Length
241 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.367 kDa
Sequence
MKKTIFVGDLHLSADRPDITQAFIYFLNHGLDNTEALYIIGDLFEVWMGDDIAESFTIAIAEAIKTVSNSIPVYFTHGNRDFMVDKQFCLRAGMKILPEVYCINLYGVNTVILHGDSLCTLDIAYQRFRRFRSLDIVRWVYSHLPKKTRLNIAAKIRQKSVQGNQQKHYEIMDVESSAVTALLASTGCQRMIHGHTHRPAIHQLTAQEQRVVVGDWYTQGSVLNVSEKGCELVTLPFSETN

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.428 kDa
Sequence
MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQIAAALKSLQQHGVPCYFIHGNRDFLLGKRFAVESGMTLLPEEKVVDLYGRKIVILHGDTLCTDDADYQHFRRRVHNPIIQKLFLWLPLRFRLRIAAYMRNQSQQNNSGKSQLIMDVNPHAVVETFERNSVSWMIHGHTHRPAVHTVELASTTAHRVVLGAWHVEGSMVKVTADKVELIKFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Klebsiella pneumoniae (strain 342)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.177 kDa
Sequence
MATLFIADLHLQTEEPAITAGFLRFLQGEARQADALYILGDLFEAWIGDDDPNPLHQQIASAIKAVVDAGVPCYFIHGNRDFLVGQRFARQSGMLLLAEEERLDLYGREVLIMHGDTLCTDDQNYLAFRAKVHTPWIQRLFLALPLFIRRRIAARMRADSKAANSSKSMDIMDVNPQAVVDVMERHHVQWLIHGHTHRPAVHELQANGQPAWRVVLGAWHSEGSMVKVTPDDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.087 kDa
Sequence
MATLFIADLHLQTEEPAITAGFLRFLQGEARQADALYILGDLFEAWIGDDDPNPLHQQIASAIKAVVDAGVPCYFIHGNRDFLVGQRFARQSGMILLAEEERLDLYGREVLIMHGDTLCTDDQGYLAFRAKVHTPWIQRLFLALPLFIRHRIAARMRADSKAANSSKSMEIMDVNPQAVVDAMERHHVQWLIHGHTHRPAVHELQANGQPAWRVVLGAWHSEGSMVKVTPDDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Mannheimia succiniciproducens (strain MBEL55E)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
28.412 kDa
Sequence
MKKTYFISDLHLSENRPKLTALFEHFMHNIAPQAQAVYILGDLFDFWVGDDEKSPLISRVQAQIKQLTEKNIPCYFIHGNRDFLLGEKFAESCGLQLLPDYKIVNLYGTDTLICHGDTLCTDDVNYQTFRRKVHQKWRQRLFLLLPLKVRIKIADKIRRQSRHDKKMKSAEIMDVNGEFVCQIFERFNVRQMIHGHTHRQNIHQIPPHFKRIVLGDWHDDYASILEVSEQETYFLPQTAR

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.652 kDa
Sequence
MRPSYFISDLHLSEKHPELTELLLRFLRSAAAGQARAVYILGDLFDFWVGDDEVSELNTSVAREIRKLSDKGVAVFFVRGNRDFLIGRDFCRQAGMTLLPDYSVLDLFGSNTLICHGDTLCTDDKAYLRFRRIVHCRRLQKLFLMLPLKWRTRLAAKIRRVSKMEKQVKPADIMDVNAAFTARQVRAFNAERLIHGHTHREHIHHENGFTRIVLGDWHNDYASILRVDGDGAVFVPPEEC

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Neisseria meningitidis serogroup C (strain 053442)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.683 kDa
Sequence
MKPAYFISDLHLSEKHPELTALLLRFLRSSAAGQARAVYILGDLFDFWVGDDEVSELNTSVAREIRKLSDKGVAVFFVRGNRDFLIGQDFCRQAGMTLLPDYSVLDLFGCKTLICHGDTLCTDDRAYQRFRKIVHRKRLQKLFLMLPLKWRTRLAAKIRRVSKMEKQVKPADIMDVNAAFTARQVRAFNAERLIHGHTHREHIHHENGFTRIVLGDWHNDYASILRVDGDGAVFVPLEKY

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.697 kDa
Sequence
MKPAYFISDLHLSEKHPELTALLLRFLRSSAAGQARAIYILGDLFDFWVGDDEVSELNTSVAREIRKLSDKGVAVFFVRGNRDFLIGQDFCRQAGMTLLPDYSVLDLFGCKTLICHGDTLCTDDRAYQRFRKIVHRKRLQKLFLMLPLKWRTRLAAKIRRVSKMEKQVKPADIMDVNAAFTARQVRAFNAERLIHGHTHREHIHHENGFTRIVLGDWHNDYASILRVDGDGAVFVPLEKY

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Neisseria meningitidis serogroup B (strain MC58)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.661 kDa
Sequence
MKPAYFISDLHLSEKQPELTALLLRFLRSSAAGQARAIYILGDLFDFWVGDDEVSELNTSVAREIRKLSDKGVAVFFVRGNRDFLIGQDFCRQAGMTLLPDYSVLDLFGCKTLICHGDTLCTDDRAYQRFRKIVHRKRLQKLFLMLPLKWRTRLATKIRRVSKMEKQVKPADIMDVNAAFTARQVRAFGAERLIHGHTHREHIHHENGFTRIVLGDWHNDYASILRVDGDGAVFVPLEKY

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.656 kDa
Sequence
MKPAYFISDLHLSEKHPELTALLLRFLRSSAAGQARAVYILGDLFDFWVGDDEVSELNTSVAREIRKLSDKGVAVFFVRGNRDFLIGQDFCRQAGMTLLPDYSVLDLFGCKTLICHGDTLCTDDRAYQRFRKIVHRKRLQKLFLMLPLKWRTRLATKIRRVSKMEKQVKPADIMDVNAAFTARQVRAFGAERLIHGHTHREHIHHENGFTRIVLGDWHNDYASILRVDGDGAVFVPLEKY

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.433 kDa
Sequence
MATLFIADLHLSLHEPAITAGFLRFLRHEAIHADALYILGDLFDTWIGDDDPQPLHATIAAELYALHQLGITCYFVHGNRDFLIGKRFARQSGMTLLPTENVVDLYGQKILILHGDTLCTDDLAYQKFRRRVHNPFIQQLFLLLPLSLRLKIAAKMRASSQQANQQKSQQIMDVNPEQVLERLRHYQVKTMIHGHTHRPAIHQVDLGKSYGRRAVLGAWHEEGSMIKVTPQNIELISFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pectobacterium carotovorum subsp. carotovorum (strain PC1)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.549 kDa
Sequence
MATLFIADLHLSLHEPAITAGFLRFLRHDAIHADALYILGDLFDAWIGDDDPQPLHATIAAELYVLHQRGIPCYFVHGNRDFLIGKRFAKQSGMTLLPTETVLDLYGQKILILHGDTLCTDDHHYQQFRRRVHNPFIQRLFLLLPLSSRVKIAAKMRATSQQENQKKSQQIMDVNHDAVLERLRHYQVKTMIHGHTHRPAIHQVDLGESYGRRAVLGAWHEEGSMIKVTPQNIELISFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.845 kDa
Sequence
MCTLFIADLHLSEHEPAITAGFLRFLREDAIQADSLYILGDLFDYWIGDDDNNPLHREIASALKTVQQQGVSCYFIHGNRDFLLGSRFAKESGIILLPQEKVLELYGKRVLILHGDTLCTDDEGYQRYRKRVHTPWIQRLFLLLPLSIRQKIAVKMRANSQSVNRRKSEAIMDVNQQAVIDTFERYQADWMIHGHTHRPFVHEVPLHDKTVYRGVLGAWHHQGSMFKITDKSIDLISFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Proteus mirabilis (strain HI4320)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.727 kDa
Sequence
MCTLFIADLHLSEHEPAITAGFLRFLQEQAIHANALYILGDFFDFWIGDDDPNPLHQRIAQALMALKNAGVPCYFIHGNRDFLIGSRFAKESGMTLLPQEKVLEIEQHRILILHGDTLCTDDDAYQRYRKKVHNKFIQRLFLLLPLTIRLRIAKKMRSRSQSSNQYKSEAIMDVNAQAVINTFKQFNTQWMIHGHTHRPAIHTVDIDGKPHYRGVLGAWHTEGSMFKVTSDKIELIQFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas aeruginosa (strain PA7)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.467 kDa
Sequence
MSVLFISDLHLEAERPDITRAFLSFLDERARRAEALYILGDFFEAWIGDDGMDAFQHSIASALRQVADGGTRLYLMHGNRDFLIGQAFCREAGCTLLPDPSVIDLYGEPVLLMHGDSLCTRDEAYMRLRRWLRNPLTLWVLRHLPLATRHKLARKLRKESRAQTRMKAVDIIDVTPDEVPLAMRRHGVRTLIHGHTHRPAEHALEVDGQPARRIVLGDWDRQGWALEIDANGHRQAPFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas aeruginosa (strain LESB58)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.555 kDa
Sequence
MSVLFISDLHLEAERPDITRAFLSFLDERARRAEALYILGDFFEAWIGDDGMDAFQRSIAQSLRQVADGGTRIYLMHGNRDFLIGKAFCREAGCTLLPDPSVIDLYGEPVLLMHGDSLCTRDEAYMRLRRWLRNPLTLWVLRHLPLATRHKLARKLRKESRAQTRMKAVDIIDVTPEEVPRVMRGHGVRTLIHGHTHRPAEHPLDIDGQPARRIVLGDWDRQGWALEIDANGHRQAPFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas aeruginosa (strain UCBPP-PA14)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.555 kDa
Sequence
MSVLFISDLHLEAERPDITRAFLSFLDERARRAEALYILGDFFEAWIGDDGMDAFQRSIAQSLRQVADGGTRIYLMHGNRDFLIGKAFCREAGCTLLPDPSVIDLYGEPVLLMHGDSLCTRDEAYMRLRRWLRNPLTLWVLRHLPLATRHKLARKLRKESRAQTRMKAVDIIDVTPEEVPRVMRGHGVRTLIHGHTHRPAEHPLDIDGQPARRIVLGDWDRQGWALEIDANGHRQAPFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Can functionally complement lpxH deficiency in E.coli.
Similarity
Belongs to the LpxH family.
Mass
27.555 kDa
Sequence
MSVLFISDLHLEAERPDITRAFLSFLDERARRAEALYILGDFFEAWIGDDGMDAFQRSIAQSLRQVADGGTRIYLMHGNRDFLIGKAFCREAGCTLLPDPSVIDLYGEPVLLMHGDSLCTRDEAYMRLRRWLRNPLTLWVLRHLPLATRHKLARKLRKESRAQTRMKAVDIIDVTPEEVPRVMRGHGVRTLIHGHTHRPAEHPLDIDGQPARRIVLGDWDRQGWALEIDANGHRQAPFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas entomophila (strain L48)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.262 kDa
Sequence
MILLISDLHLQEERPDITRAFLDLLDGRARHAKALYILGDFFEAWIGDDAMTPFQRSICQALRQLSDSGTTIYLMHGNRDFLIGQAFCQAAGCTLLDDPSVIELGGEAVLLMHGDTLCTRDVGYMKLRRYLRNPLSLWILRHLPLSTRQKLARKLRSESKSQTRMKNTEIVDVTPDEVPKVMAAHGVRTLVHGHTHRPAIHKLVIDGQPARRIVLGDWDRRGWALQVDEQGFQLAPFEFS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.253 kDa
Sequence
MILLISDLHLQEERPDISRAFLDLLDGRARHAKALYILGDFFEAWIGDDAMTPFQQSICQAMRRLSDSGTAIYLMHGNRDFLIGQAFCDAAGCTLLSDPSVIELGGEQVLLMHGDTLCTRDLGYMKMRRLLRNPLSLWILRHLPLSARYKLARKLRSESRTQVRMKSTEIVDVTPEEVPKVMAAHGVRTLVHGHTHRPAIHKLVVDGQPARRIVLGDWDRRGWALQVDEQGFQLAPFEFS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas putida (strain GB-1)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.303 kDa
Sequence
MILLISDLHLQEERPDISRAFLDLLDGRARHAKALYILGDFFEAWIGDDAMTPFQQSICQAMRRLSDSGTAIYLMHGNRDFLIGQAFCDAAGCTLLSDPSVIELGGEQVLLMHGDTLCTRDLGYMKMRRLLRNPLSLWILRHLPLSSRYKLARKLRSESRTQTRMKSTEIVDVTPEEVPKVMAAHGVRTLVHGHTHRPAIHKLMVDGQPARRIVLGDWDRRGWALQVDEQGFQLAPFEFS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.325 kDa
Sequence
MILLISDLHLQEERPDISRAFLDLLDGRARHAKALYILGDFFEAWIGDDAMTPFQQSICQAMRRLSDSGTAIYLMHGNRDFLIGQAFCKAAGCTLLNDPSVIELGGEQVLLMHGDTLCTRDLGYMKMRRLLRNPLSLWILRHLPLSARYKLARKLRSESRTQVRMKSTEIVDVTPEEVPKVMAAHGVRTLVHGHTHRPAIHKLMVDGQPARRIVLGDWDRRGWALQVDEQGFQLAPFEFS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas putida (strain W619)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.064 kDa
Sequence
MILLISDLHLQEERPDITRAFLDLLDGRARHAKALYILGDFFEAWIGDDAMTPFQQSICQAVRQLSDSGTAVYLMHGNRDFLIGEGFCKAAGCTLLADPSVISLGGEQVLLMHGDTLCTRDIGYMKMRRYLRNPLSLWILRHLPLATRQKLARKLRSESRAQTRMKATEIVDVTPEEVPAVMAAHGVKTLVHGHTHRPAIHKLVVNGEPARRIVLGDWDRRGWTLQVDAQGFQLEPFEFS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas stutzeri (strain A1501)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.373 kDa
Sequence
MILLISDLHLEEERPDITRAFLHFLATRATQAEALYILGDFFEVWIGDDAMTPFQESIARALHALSERGVRIYLMHGNRDFMIGQTFCHKAGCKLLADPSVVQLCGEPVLLMHGDSLCTRDEGYMRLRRLLRNPLSLFVLRNLPLATRRKLARKLRNESRTQTRMKASDIIDVTPELIPGVLAEHRVRTLIHGHTHRPATHDLEVDGQPAKRIVLGDWDRQGWALQVDENGYHQAPFALS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella agona (strain SL483)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.927 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREIAAAIKAVVNVGVPCFFIHGNRDFLIGKRFARESGMILLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLVHGHTHRPAVHELSVNDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.89 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMTLLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARLRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANGQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas aeruginosa (strain PA7)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.467 kDa
Sequence
MSVLFISDLHLEAERPDITRAFLSFLDERARRAEALYILGDFFEAWIGDDGMDAFQHSIASALRQVADGGTRLYLMHGNRDFLIGQAFCREAGCTLLPDPSVIDLYGEPVLLMHGDSLCTRDEAYMRLRRWLRNPLTLWVLRHLPLATRHKLARKLRKESRAQTRMKAVDIIDVTPDEVPLAMRRHGVRTLIHGHTHRPAEHALEVDGQPARRIVLGDWDRQGWALEIDANGHRQAPFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas aeruginosa (strain LESB58)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.555 kDa
Sequence
MSVLFISDLHLEAERPDITRAFLSFLDERARRAEALYILGDFFEAWIGDDGMDAFQRSIAQSLRQVADGGTRIYLMHGNRDFLIGKAFCREAGCTLLPDPSVIDLYGEPVLLMHGDSLCTRDEAYMRLRRWLRNPLTLWVLRHLPLATRHKLARKLRKESRAQTRMKAVDIIDVTPEEVPRVMRGHGVRTLIHGHTHRPAEHPLDIDGQPARRIVLGDWDRQGWALEIDANGHRQAPFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas aeruginosa (strain UCBPP-PA14)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.555 kDa
Sequence
MSVLFISDLHLEAERPDITRAFLSFLDERARRAEALYILGDFFEAWIGDDGMDAFQRSIAQSLRQVADGGTRIYLMHGNRDFLIGKAFCREAGCTLLPDPSVIDLYGEPVLLMHGDSLCTRDEAYMRLRRWLRNPLTLWVLRHLPLATRHKLARKLRKESRAQTRMKAVDIIDVTPEEVPRVMRGHGVRTLIHGHTHRPAEHPLDIDGQPARRIVLGDWDRQGWALEIDANGHRQAPFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Can functionally complement lpxH deficiency in E.coli.
Similarity
Belongs to the LpxH family.
Mass
27.555 kDa
Sequence
MSVLFISDLHLEAERPDITRAFLSFLDERARRAEALYILGDFFEAWIGDDGMDAFQRSIAQSLRQVADGGTRIYLMHGNRDFLIGKAFCREAGCTLLPDPSVIDLYGEPVLLMHGDSLCTRDEAYMRLRRWLRNPLTLWVLRHLPLATRHKLARKLRKESRAQTRMKAVDIIDVTPEEVPRVMRGHGVRTLIHGHTHRPAEHPLDIDGQPARRIVLGDWDRQGWALEIDANGHRQAPFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas entomophila (strain L48)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.262 kDa
Sequence
MILLISDLHLQEERPDITRAFLDLLDGRARHAKALYILGDFFEAWIGDDAMTPFQRSICQALRQLSDSGTTIYLMHGNRDFLIGQAFCQAAGCTLLDDPSVIELGGEAVLLMHGDTLCTRDVGYMKLRRYLRNPLSLWILRHLPLSTRQKLARKLRSESKSQTRMKNTEIVDVTPDEVPKVMAAHGVRTLVHGHTHRPAIHKLVIDGQPARRIVLGDWDRRGWALQVDEQGFQLAPFEFS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.253 kDa
Sequence
MILLISDLHLQEERPDISRAFLDLLDGRARHAKALYILGDFFEAWIGDDAMTPFQQSICQAMRRLSDSGTAIYLMHGNRDFLIGQAFCDAAGCTLLSDPSVIELGGEQVLLMHGDTLCTRDLGYMKMRRLLRNPLSLWILRHLPLSARYKLARKLRSESRTQVRMKSTEIVDVTPEEVPKVMAAHGVRTLVHGHTHRPAIHKLVVDGQPARRIVLGDWDRRGWALQVDEQGFQLAPFEFS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas putida (strain GB-1)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.303 kDa
Sequence
MILLISDLHLQEERPDISRAFLDLLDGRARHAKALYILGDFFEAWIGDDAMTPFQQSICQAMRRLSDSGTAIYLMHGNRDFLIGQAFCDAAGCTLLSDPSVIELGGEQVLLMHGDTLCTRDLGYMKMRRLLRNPLSLWILRHLPLSSRYKLARKLRSESRTQTRMKSTEIVDVTPEEVPKVMAAHGVRTLVHGHTHRPAIHKLMVDGQPARRIVLGDWDRRGWALQVDEQGFQLAPFEFS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.325 kDa
Sequence
MILLISDLHLQEERPDISRAFLDLLDGRARHAKALYILGDFFEAWIGDDAMTPFQQSICQAMRRLSDSGTAIYLMHGNRDFLIGQAFCKAAGCTLLNDPSVIELGGEQVLLMHGDTLCTRDLGYMKMRRLLRNPLSLWILRHLPLSARYKLARKLRSESRTQVRMKSTEIVDVTPEEVPKVMAAHGVRTLVHGHTHRPAIHKLMVDGQPARRIVLGDWDRRGWALQVDEQGFQLAPFEFS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas putida (strain W619)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.064 kDa
Sequence
MILLISDLHLQEERPDITRAFLDLLDGRARHAKALYILGDFFEAWIGDDAMTPFQQSICQAVRQLSDSGTAVYLMHGNRDFLIGEGFCKAAGCTLLADPSVISLGGEQVLLMHGDTLCTRDIGYMKMRRYLRNPLSLWILRHLPLATRQKLARKLRSESRAQTRMKATEIVDVTPEEVPAVMAAHGVKTLVHGHTHRPAIHKLVVNGEPARRIVLGDWDRRGWTLQVDAQGFQLEPFEFS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pseudomonas stutzeri (strain A1501)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.373 kDa
Sequence
MILLISDLHLEEERPDITRAFLHFLATRATQAEALYILGDFFEVWIGDDAMTPFQESIARALHALSERGVRIYLMHGNRDFMIGQTFCHKAGCKLLADPSVVQLCGEPVLLMHGDSLCTRDEGYMRLRRLLRNPLSLFVLRNLPLATRRKLARKLRNESRTQTRMKASDIIDVTPELIPGVLAEHRVRTLIHGHTHRPATHDLEVDGQPAKRIVLGDWDRQGWALQVDENGYHQAPFALS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella agona (strain SL483)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.927 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREIAAAIKAVVNVGVPCFFIHGNRDFLIGKRFARESGMILLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLVHGHTHRPAVHELSVNDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.89 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMTLLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARLRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANGQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.924 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shigella boydii serotype 4 (strain Sb227)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.924 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shigella dysenteriae serotype 1 (strain Sd197)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.924 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARNADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESDMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHNPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shigella flexneri serotype 5b (strain 8401)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.924 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shigella flexneri
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.924 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shigella sonnei (strain Ss046)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.938 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDEPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli O9:H4 (strain HS)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.894 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRKMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli O1:K1 / APEC
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.875 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHHQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli O6:K15:H31 (strain 536 / UPEC)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.879 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHHQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQTAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.851 kDa
Sequence
MATLFIADLHLCAEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHHQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQTAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.894 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRKMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli (strain K12)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom (PubMed:12000770). Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (PubMed:12000770, PubMed:12000771). Is essential for E.coli growth (PubMed:12000771). Does not cleave the unacylated UDP-GlcNAc, the mono-acylated UDP-3-O-(R)-3-hydroxymyristoyl-GlcNAc, and CDP-diacylglycerol (PubMed:12000770).
Similarity
Belongs to the LpxH family.
Mass
26.894 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRKMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.866 kDa
Sequence
MATLFIADLHLCAEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli (strain SE11)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.894 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli (strain SMS-3-5 / SECEC)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.894 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli (strain UTI89 / UPEC)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.875 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHHQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Enterobacter sp. (strain 638)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.716 kDa
Sequence
MATLFIADLHLQTEEPAITAGFLHFLQGEARSADALYILGDLFEAWIGDDDPNPLHHDMAAAIKALVDSGVPCYFIHGNRDFLIGKRFARESGMTLLPDENVLELYGRNVLIMHGDTLCTDDTGYLAFRAKVHTPWIQTLFLALPLFIRNRIAAKMRAGSKAANSSKSMTIMDVNPQAVVEVMEKHRVQWLIHGHTHRPDVHQLTANGEPAHRVVLGAWHSEGSMVKVTSEGVELIQFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.936 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDIGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Cellvibrio japonicus (strain Ueda107)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.872 kDa
Sequence
MNTLFISDLHLHSSRPQITRAFFDFLRQQTHHTQALYILGDFFDAWIGDDDDDPLPNAVAEQLKKLNSAGVAIFLMHGNRDFLLGNSYAQRAGATLIAEGTVIDLYGRPALLLHGDDLCTLDTDYMAFRQQVRNPDWQAQLLAQPLAARRALAAQLRAQSQAINNMKAESIMDVTPDEVVRVMEEAGVDLLIHGHTHRPARHPLTVQGRPAERIVLGDWHHQGWCLDASATGLALRNWDI

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Cronobacter sakazakii (strain ATCC BAA-894)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.88 kDa
Sequence
MATLFIADLHLCSEEPAITAGFLRFLAGTAREADALYILGDLFEAWIGDDDPEPLHREIAAALRALVQSGVPCYFIHGNRDFLLGRRFARESGMQLLPEEQVLDLYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLRLRRRIAARMRAGSKASNSQKDLAIMDVNPQAVVDTMERQQVQWLIHGHTHRPAVHTLEANGKPAHRVVLGAWHSEGSMVKVTPDNVELVAFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli O139:H28 (strain E24377A / ETEC)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.924 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.902 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHHQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVNAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli O45:K1 (strain S88 / ExPEC)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.875 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHHQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli (strain 55989 / EAEC)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.924 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli O157:H7
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.952 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRTKVHKPWLQTLFLALPLFVRKRIAVRMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli O157:H7 (strain EC4115 / EHEC)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.952 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRTKVHKPWLQTLFLALPLFVRKRIAVRMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli O7:K1 (strain IAI39 / ExPEC)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.007 kDa
Sequence
MATLFIADLHLCAEEPAITAGFLRFLAREARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDIGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli O81 (strain ED1a)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.87 kDa
Sequence
MATLFIADLHLCAEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQTAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli O8 (strain IAI1)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.924 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli (strain K12 / MC4100 / BW2952)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.894 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRKMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Escherichia coli (strain K12 / DH10B)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.894 kDa
Sequence
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRKMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.425 kDa
Sequence
MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSEHIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Yersinia pestis bv. Antiqua (strain Antiqua)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.444 kDa
Sequence
MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSERIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Yersinia pseudotuberculosis serotype IB (strain PB1/+)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.444 kDa
Sequence
MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSERIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Yersinia pestis
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.444 kDa
Sequence
MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSERIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Yersinia pestis bv. Antiqua (strain Angola)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.444 kDa
Sequence
MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSERIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Yersinia pestis bv. Antiqua (strain Nepal516)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.444 kDa
Sequence
MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSERIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Yersinia pestis (strain Pestoides F)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.444 kDa
Sequence
MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSERIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Yersinia pseudotuberculosis serotype I (strain IP32953)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.444 kDa
Sequence
MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSERIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.444 kDa
Sequence
MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSERIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella choleraesuis (strain SC-B67)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.992 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMILLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLVHGHTHRPAVHELSVNDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella dublin (strain CT_02021853)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.913 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREIAAAIKAVVNVGVPCFFIHGNRDFLIGKRFARESGMILLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella enteritidis PT4 (strain P125109)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.966 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMTLLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella gallinarum (strain 287/91 / NCTC 13346)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.966 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMTLLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella heidelberg (strain SL476)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.978 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMILLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella newport (strain SL254)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.978 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMILLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella paratyphi A (strain ATCC 9150 / SARB42)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.966 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMTLLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.966 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMTLLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella paratyphi C (strain RKS4594)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.992 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMILLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLVHGHTHRPAVHELSVNDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella paratyphi A (strain AKU_12601)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.966 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMTLLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella schwarzengrund (strain CVM19633)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.978 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMILLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWIQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLVHGHTHRPAVHELSANDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella typhi
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.892 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMTLLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRPFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANGQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.978 kDa
Sequence
MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMILLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Serratia proteamaculans (strain 568)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.226 kDa
Sequence
MNTLFIADLHLSAQEPAITAGFLRFLRQDAIHADALYILGDLFEAWIGDDDPEPLHGEIAAALKALQQAGVPCYFIHGNRDFLVGKRFARTSGMQLLPEEQVLDLYGRKILILHGDTLCTDDQAYQQFRRKVHNPLIQKLFLAMPLRWRLKIAAKMRARSQQSNQYKSDSIMDVNPQAVEQAMLRHKVHWMIHGHTHRPAVHELALSNGKAHRVVLGAWHVEGSMIKVSADAVELIQFPF

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shewanella baltica (strain OS223)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.08 kDa
Sequence
MRTLFIGDLHLSADRLDITQAFTRFLDTELDDADALYILGDLFEVWVGDDIALPFALELAEKLKQVSQKLPVYFIHGNRDFMLGKQFARAAGMQILPEVKCLNLYGIETVILHGDSLCTLDKAYQRFRKLRSLSLARWLYGCLSKKTRQGIADKIRSNSKSSNQQKSYTIMDVEPNAVDALFAKTHTKHMIHGHTHRPAIHQLANGCQRIVVGDWYEQGSVLSVSAEGINLQSLPFEQAT

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shewanella baltica (strain OS155 / ATCC BAA-1091)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.099 kDa
Sequence
MRTLFIGDLHLSADRLDITQAFTRFLDTELDDADALYILGDLFEVWVGDDIALPFALELAEKLKQVSQKLPVYFIHGNRDFMLGKQYARAAGMQILPEVTCLNLYGIETVILHGDSLCTLDKAYQRFRKLRSLSLARWLYGCLSKKTRQGIADKIRSNSKSSNQQKSYTIMDVEPNAVDALFAKTHTKHMIHGHTHRPAIHQLANGCQRIVVGDWYEQGSVLSVSAEGINLQSLPFEQTT

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shewanella baltica (strain OS185)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.121 kDa
Sequence
MRTLFIGDLHLSADRLDITQAFTRFLDTELDDADALYILGDLFEVWVGDDIALPFALELAEKLKQVSQKLPVYFIHGNRDFMLGKQFARAAGMQILPEVTCLNLYGVETVILHGDSLCTLDKAYQRFRKLRSLSLARWLYGCLSKKTRQGIADKIRSNSKSSNQQKSYTIMDVEPNAVDALFAKTHTKHMIHGHTHRPAIHLLANDCQRIVVGDWYEQGSVLSVSAEGINLQSLPFEHTT

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shewanella baltica (strain OS195)
Length
240 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.092 kDa
Sequence
MRTLFIGDLHLSADRLDITQAFTRFLDTELDDADALYILGDLFEVWVGDDIALPFALELAEKLKQVSQKLPVYFIHGNRDFMLGKQFARAAGMQILPEVTCLNLYGIETVILHGDSLCTLDKAYQRFRKLRSLSLARWLYGCLSKKTRQGIADKIRSNSKSSNQQKSYTIMDVEPNAVDALFAKTHTKHMIHGHTHRPAIHQLANGCQRIVVGDWYEQGSVLSVSAEGINLQSLPFEHTT

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Pasteurella multocida (strain Pm70)
Length
239 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.854 kDa
Sequence
MKKTYFIADLHLSENRPHLTHLFCDFMQQLAPQAEALYILGDLFDFWIGDDEESALIHTVQQQIHALSAQGVKCYFQHGNRDFLIGKRFAAACGMTLLPTYQRIALYGESVLLCHGDTLCIDDVAYQQYRKKVHQKWRQWLFLHLPLKVRLKIAEKIRARSKADKKRKSEEIMDVNPDFVLQTFAQFGVKKIIHGHTHRQHIHHIPPHFTRIVLGDWGDTASILEVNEQQQVRFLTGKE

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shewanella oneidensis (strain MR-1)
Length
239 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.013 kDa
Sequence
MRTLFIGDLHLSADRLDITQAFNRFLDTELDDADALYILGDLFEVWVGDDLAAPFALELAHKLKQVSQTLPIFFIHGNRDFMLGKRFAEAAGMQLLPEVTCIELYGVKTVILHGDSLCTLDKAYQRFRKLRSFACARWLYSCLPKKRRQAIANKIRSNSQSSNQQKSYVIMDVEPSAVNALFVKTHTTRMIHGHTHRPAIHIVDNACQRIVVGDWYEQGSVLSVSANGVDLKSLPFETT

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shewanella sp. (strain ANA-3)
Length
239 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.048 kDa
Sequence
MRTLFIGDLHLSADRLDITQAFNRFLDTELDDADALYILGDLFEVWVGDDLAAPFALELARKLNQVSQRLPIYFIHGNRDFMLGKQFADVAGMQMLPEVTCLDLYGVNTVILHGDSLCTLDKAYQRFRKLRSFAFARWLYSCLPKKKRQAIANKIRSNSQSSNQQKSYVIMDVEPSAVDALFAQSHCKQMIHGHTHRPAIHEFTNGCKRIVVGDWYEQGSVLVVSSDGVDLKSLPFDAS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shewanella sp. (strain MR-4)
Length
239 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.09 kDa
Sequence
MRTLFIGDLHLSADRLDITKAFNRFLDTELDDADALYILGDLFEVWVGDDLAAPFALELARRLKQISQRLPIYFIHGNRDFMLGKQFTDAAGMQMLPEVTCLDLYGVSTVILHGDSLCTLDKAYQRFRKLRSFAFARWLYSCLPKRKRQAIANKIRSNSQSSNQQKSYVIMDVEPSAVDALFAQTHCKQMIHGHTHRPAIHNFTNGCKRIVVGDWYEQGSVLVVSADGVDLKSLPFDAS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shewanella sp. (strain MR-7)
Length
239 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.088 kDa
Sequence
MRTLFIGDLHLSADRLDITQAFNRFLDTELDDADALYILGDLFEVWVGDDLAAPFALELARRLKQISQRLPIYFIHGNRDFMLGKQFADAAGMQILPEVTCLDLYGVNTVILHGDSMCTLDKAYQRFRKLRSFAFARWLYSCLPKRKRQAIADKIRSNSQSSNQQKSYVIMDVEPSAVDALFAQTHCKQMIHGHTHRPAIHNFTNGCKRIVVGDWYEQGSVLVVSADGVDLKSLPFDAS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Sodalis glossinidius (strain morsitans)
Length
239 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.812 kDa
Sequence
MSTLFVADIHLCAQEPAITAGFLHFLRTRAIAAQALYILGDLFEVWIGDDDPNPLHHEIAVALQALTQRGIPCYFIHGNRDFLLGKRYAAACGITLLPAQRVMQLDELRVVILHGDTLCTDDNDYQRFRRRVHQRWLQRLFLSLPLQLRLRIADRMRANSLRANAGKTADIMDINAQAVMAVMDDTGATVMIHGHTHRPAIHQLPGERRRAVLGAWHHQGSAIEVSTSGVMLHEFSFGG

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shewanella halifaxensis (strain HAW-EB4)
Length
238 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.3 kDa
Sequence
MRTLFVGDLHLSTDRPDITQAFLRFLDTQLHDTDALYILGDLFEVWVGDDIAEPFAEQLAKAIYQASQKLPIFFIHGNRDFLISNAFAKRSGMTLLPEIYTVDLYGIPTVILHGDSLCTLDKPYQRFRKFRNLGWAKWLYAHLPKSKRLDIAVKLRSKSQSSNQQKSYSIMDVEPDAVLELLNATKTEQMIHGHTHRPAIHQLANGRRRIVVGDWYEQGSMLSVSQDKIELIELPFGK

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)
Length
238 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.029 kDa
Sequence
MRTLFVGDLHLSADRPDITQAFLEFLDTQLHDTDALYILGDLFEVWVGDDIAEPFVNQLVDAIKHASEKLPVYFIHGNRDFLIGEAFAKRCGMTLLPEVYSLDLYGVSTVILHGDSLCTLDKSYQRFRAFRNQGWAKWLYAHLPKSKRLGIAAKLRAKSQSSNQQKSYTIMDVEPDAVMDLLDATQTQQMIHGHTHRPDIHQLAHGKRRIVVGDWYEQGSMLSVSQDGVELIELPFGK

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shewanella piezotolerans (strain WP3 / JCM 13877)
Length
238 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.206 kDa
Sequence
MRTLFVGDLHLSADRPDITQAFLTFLETQLTDTSALYILGDLFEVWVGDDIAEPFANQLADAIKLASKKLPIYFIHGNRDFLIGERFAQRSGMTLLPEVYKLDLYGTTTVLLHGDSLCTLDKPYQRFRKFRNLSWAKWIYNHLPKSKRLNIAAKLRSKSQSSNQHKSYSIMDVEPSAVLELLDNTNAQQMIHGHTHRPAIHQLSNGKRRIVVGDWYEQGSMLCISQDNVELIELPFGK

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Length
238 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.866 kDa
Sequence
MRTLFIGDLHLSADRPDITSAFRRFLSQSFDDVDALYILGDLFEVWVGDDIAEPFALDIAADIAALSHKLPIYFIHGNRDFLIGKQFAAISKMQLLDEVHQINLYGIPTLLLHGDSLCTLDKGYQRFRWFRNQPWVKWIYSKLSQSKRLSIAANLRAKSKAGNQLKSQYIMDAEPHAVADLLQKHSCRQMIHGHTHRPAIHHESAGTRIVVGDWYSQSSVLEMTAEGPNLQAKPLGGS

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Haemophilus influenzae (strain 86-028NP)
Length
237 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.781 kDa
Sequence
MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSALIQQVKDLIKSVSNQGVQCYFQHGNRDFLIGERFAKDTGVQLLPDYQLITLYDKKILLCHGDTLCIDDEAYQQFRRRVHQKWLQRLFLCLPLKVRVIIAEKIRAKSNQDKQAKSQEIMDVNQAFTAEKVQEFDVNLLIHGHTHREAIHQQEEFTRIVLGDWRKNYASILKMDESGEFGFIKD

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Haemophilus influenzae (strain PittEE)
Length
237 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.711 kDa
Sequence
MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSTLIQQVKDLIKSVSEQGVQCYFQHGNRDFLIGERFAKDTGVQLFPDYQLITLYDKKILLCHGDTLCIDDVAYQQFRRRVHQKWLQRLFLCLPLKVRLKIAEKIRAKSNQDKQAKTQEIMDINQAFTTEKVQEFGVNLLIHGHTHREAIHQQAGFTRIVLGDWRKNYASILKIDESGEFGFIKD

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Haemophilus influenzae (strain PittGG)
Length
237 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.726 kDa
Sequence
MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSTLIQQVKDLIKSVSNQGVQCYFQHGNRDFLIGERFSKETGAQLLPDYQLITLYDKKILLCHGDTLCIDDVAYQQFRRRVHQKWLQRLFLCLPLKVRLKIAEKIRAKSNQDKQAKSQEIMDINQAFTTEKVQEFGVNLLIHGHTHREAIHQQEGFTRIVLGDWRKNYASILKMDESGEFGFIKD

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Length
237 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.786 kDa
Sequence
MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSALIQQVKDLIKFVSDQGVQCYFQHGNRDFLIGERFSKETGAQLLPDYQLITLYDKKILLCHGDTLCIDDEAYQQFRRRVHQKWLQRLFLCLPLKVRVIIAEKIRAKSNQDKQAKSQEIMDVNQAFTAEKVQEFGVNLLIHGHTHREAIHQQEEFTRIVLGDWRKNYASILKMDESGEFGFIKD

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
Length
237 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
26.325 kDa
Sequence
MAIHFISDLHLADDTPALNQLFLDTLAAWRGRIAALYILGDLFEYWVGDDDDSPYLAAPLAAMRDFAAQTPLYVMRGNRDFLLGAGFEARSGARLLDDPTLIEAHGQRILLSHGDALCTDDAAYQQFRAMSRNPQWQQAMLAKPLAERHAIARHARAQSEMNKQQTGLTDISDVTENAVRELLAAHGWPTLIHGHTHRPAHHLHDASSRWVIQDWHGGRGGYLLLDDGGIRSLPLGN

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / 130Z)
Length
235 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.755 kDa
Sequence
MHKTYFIADLHLSETRPNLTALFVDFMQHLAPDADAVYILGDLFDFWIGDDERSPLIDTVKNQIRTLVQQGVPCYFIHGNRDFLLGKRFAGDCGLRLLPEYQVIDLYGEPTLICHGDTLCTDDLHYQAFRRKVHRPWLQWLFRRLPLKVRLKIAQNIRTKSSRDKQNKSQAIMDVNPEFTRRIFERFQVKRLIHGHTHRQNIHQIPPHFERIVLGDWGETASILEVTPQDIRFRQ

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Histophilus somni (strain 2336)
Length
234 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.324 kDa
Sequence
MKKTFFIADLHLSENRPHLTELFVHFMQTQAPQAEKLYILGDLFDFWIGDDEQSALIETVQQQILQLTQKGISCYFIHGNRDFLVGRQFANSCGMELLPTYQIVNLYGKKVLICHGDTLCTDDLAYQQYRKKVQQKWLQWLFLHLPLKVRLKIAEKIRQKSKTDKTHKSIEIMDVNKDFVEQIMQQFQVNILIHGHTHKQNIHQNPPHFTRIVLGDWGATASVLEVSANGFQFI

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Haemophilus ducreyi (strain 35000HP / ATCC 700724)
Length
234 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.443 kDa
Sequence
MMTYYFIADLHLNESQPQITHQFLQFMQQKAPLAQAVYILGDFFDFWIGDDEQSVLISQVKLALKKLTASGVKCYFICGNRDFLLGQTFAQQTGIQLLADYHLLDLFGERTLLCHGDTLCIDDIKYQQFRRRVHQKRLQKLFLWLPLTLRIKIAQKIRRKSKQDKKNKSADIMDVNQAFTAQKVHQYGATHLIHGHTHRQAVHFEQNFTRIVLGDWRPDRSSILKVDEKGFEFL

Gene
lpxH
Protein
UDP-2,3-diacylglucosamine hydrolase
Organism
Haemophilus somnus (strain 129Pt)
Length
234 amino acids
Function
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Similarity
Belongs to the LpxH family.
Mass
27.336 kDa
Sequence
MKKTFFIADLHLSENRPHLTELFVQFMQTQALQAEKLYILGDLFDFWIGDDEQSALIETVQQQILQLSQKGIPCYFIHGNRDFLVGRHFANSCGMELLPTYQIVNLYGKKVLICHGDTLCTDDLAYQQYRKKVQQKWLQWLFLHLPLKVRLKIAEKIRQKSKTDKTHKSIEIMDVNKDFVEQIMQQFQVNILIHGHTHKQNIHQNPPHFTRIVLGDWGATASVLEVSANGFQFI