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lonp-2

Gene
lonp-2
Protein
Lon protease homolog 2, peroxisomal
Organism
Caenorhabditis briggsae
Length
773 amino acids
Function
ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
Similarity
Belongs to the peptidase S16 family.
Mass
86.062 kDa
Sequence
MKFEESMELPVIVVDSGVLLPGASLKIPIRSKLNTRTIEQHLTRGGSNYVVIAYKLSTDKIYNVATIAYIEKLFGWTFNSTTNYSLDVIGLHRANIDKLSFPKCRVSKLEDSSERAEFNHSTIENVISGAKILAQNSESLKFSQEIHNSIDDHDYGKLADLCVSQIKNLEFSQFLDFLGTKNVEKRLEMCEKWMQMQRETKALQLKMAVPGNSEIPKKINKQRIPNSKNQVEQLEEKLSAIEFSEEVSDRVFSELHRLKNMNPQQSEYTVLMNWLELVSNLPWNTSTVDDIEINKARKILEDSHESMDDVKQRVLEHLAVCKINNSVKGMILCFTGPPGIGKTSIAKAIAESMGRKFQRVSLGGIRDESDIRGHRRTYVAAMPGRIIEALKHCKSNNPVFLLDEVDKLYSGNQGSPSAALLELLDPEQNSTFHDHYLNIPFDVSKIMFIATANDVERLEPALKDRLEIIEMSGYSMKEKVKICENHLVNRQLSKHCISPDYVNLDRHAIMAMIEEFTMEAGVRQLERNVGAVCRHVALRLAEALNSDPSADVLPDMDLPIQIGEPDIHKILKAKHMKRVKIVEKMRPLPPGVCFGLSVTTNGGRVMPIEASKCKGTGKIVTTGHLGKVLEESILVAKGWLGANAEKLGLKTLEENDIHVHLPAGAVNKDGPSAGTGLACALVSLAMGVPLRSDAAVTGEISLTGHVLAIGGVKEKVLAAQREGLRRVVLPKSNEEEYLKIDEDIRNEMDVVLADTVEDVIEAMMEKEPVLAKL
Protein
Lon protease homolog 2, peroxisomal: lonp-2

Gene
lonp-2
Protein
Lon protease homolog 2, peroxisomal
Organism
Caenorhabditis elegans
Length
773 amino acids
Function
ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
Similarity
Belongs to the peptidase S16 family.
Mass
85.613 kDa
Sequence
MKIEENMELPVILVTSGVLLPGASLKIPIRSKLNIQTIEKYLTRSSNDNYVVIAYKVSTDKVYEVATIAYVEKLFGWTFNSTVHYSLDVIGLHRANIDKLSLPTCIVSKVVDLNEAISNQNAIEKLVTGAKIIASNSLTDKFSREIYSLIDEKEYGKLADLCVSQMKFLGFMQLLEFLGANGTDARVEMCIKWMNEKKDANTLKLKVPNSLEASFPVDGKKRKIPNVKNQVEQLEEKLNAIEFSDEVSDRVYSELHRLKSMNAQQSEYNILMNWLELVSSLPWNTSTIDDIELHKARTILTESHEAMDDVKERVLEHLAVCKMNNSVKGMILCFTGPPGIGKTSIAKAIAESMGRKFQRVSLGGIRDESDIRGHRRTYVAAMPGRIIEALKTCKTNNPVFLLDEVDKLYSGNQGSPSAALLELLDPEQNSTFHDHYLNIPFDVSKIMFIATANDIDRLEPALRDRLEIIEMSGYSLKEKVKICENHLLTRQLTKHCISHDYVKLERQAIVAMIEEYTMEAGVRQLERNVGAICRNVALRLAEALNSDPGADVLPVMELPIQISASNIHKILKNKHMKRVKIVEKMRPLPAGVCFGLSVTTIGGRVMPIEASKSKGTGKIVTTGHLGKVLKESILVAKGWLSANSERLGLGTLEDQDIHVHLPAGAVNKDGPSAGTGLACALVSLATNIPLRSDAAVTGEISLTGHVLPIGGVKEKVLAAQREGLRRVVLPKSNEEEYLKMDEDIRLEMDVVLAETIEDVIGAMMDKSPVLAKL
Protein
Lon protease homolog 2, peroxisomal: lonp-2