Llgl2

Lethal(2) giant larvae protein homolog 2

1027 amino acids

Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity (By similarity).

Belongs to the WD repeat L(2)GL family.

114.323 kDa

MRRFLRTGHDPARERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAVKLYGAPGVEFMGLHKENNAVLQIHFLPGQCQLVTLLDDNSLHLWSLKVKGGVSELQEEESFTLRGPPGAAPSATQVTEILPHSSGELLYLGTESGNVFVVQLPGFRTLHDRTICSDEVLQWLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRALSHFLSSQQLENASWQRDGCLIVTCHSDGSHCQWPVSSDTQNPEPLRSSIPYGPFPCKAITKIFWLTTRQGLPFTIFQGGMPRASYGDRHCISVVHNGQQTAFDFTSRVIDFTVLSEADPAAAFDDPYALVVLAEEELVVIDLQTPGWPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNSHFSTMEWPIDGGTSLAPPPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPSENLIAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEHAVEQVEADLLQDQEGYRWKGHERLAARPGPVCFEAGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRMRRSRVSSHKRRPGGPTGEAQAQAVNIKAERTGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLRDSSRHCPSLWAGTNGGTVYAFSLRVPPAERRTDEPVRAEQAKEIQLMHRAPVVGILVLDGHNVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVGVAHFGSCRAEDYGEHHLAVLTNLGDIQVVSMPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVDSTKAKKHNRPSNGNGTGLKMTSSGHVRNSKSQSDGDEKKPGPVMEHALLNDAWVLKEIQSTLEGDRRSYGNWHPHRVAVGCRLSNGEAE

llgl2

Lethal(2) giant larvae protein homolog 2

1020 amino acids

Essential for hemidesmosome formation and maintenance of the cytoskeleton elements as well as cellular morphology in the basal epidermis during development. Also involved in regulating growth of the basal epidermis.

Belongs to the WD repeat L(2)GL family.

113.844 kDa

MKRFRRHGHESQRDKHKQDLYQFNKTVEHGFPHQPSALGFSPSLELLAIGTRSGAIKLYGAPGVEFMGLHDENAAVTQVHFLPNQVELVTLLEDNSLHMWTLRAHNSMCELLEIGRFTLSGPPGAIPSVTRVTAVLAHSSGELLLLGTEGGHVFVVEVPGFRELEENNISVEDVQNRVPEDYVGRRNLESVETLHENPLNPRQVLIGYSRGLMVLWDLDRQRPVQHFLGTQQLESVWWMEDGESILSSHSDGSYCQWTVTGEDPQTEPEKQETPYGAFPCKAISKIIQLPSKQGPPFLIFSGGMPRASYGDRHCISVIHSKTHEALDFTSRIIDFFVIREGENHKGEPSALVVLVEEELVVVDLQTEGWPVIQTPYLVPLHCSAITCSHHVSSIPLKLWERVQAAGAHQNTHYSRKPWPINGGKNLAPDPPQRDLLLTGHEDGTVRFWDASGVCLYPMYKLSTAGVFHTDADPNDNMNQGSEGEWPPFRKVGCFDPYSDDPRLGIQKIHLCKYSGYLTVAGTAGQILVLELNDEAAEQMVEATVVDLLQGQEGFRWKGQARLDVREEPVLFPPGFQPFALVQCQPPAVVTAIALHSEWKLVGFGTSHGFGLYDYNQRNNIMVKCTLNPSDQMAMEGPLSRVKSIKKSLRQSFRRIRRSRVSMRKHHTNNAAKLQEINARLEAEALQEMELAPVQRKIEARSSDDSFTGLVRTLYFADTFVSDSSHSTPSLWAGTNGGAVFAYVLRVPPQERRAEDPVTAHAAKEIQLMHRAPVVGLVVLDGKGAPLPEPLEVAHDLARSPEMHGSHHLLVVSEEQFKLFTLPKVSSKSKLKLTAVDGSRVRRVGVAWFGSRTDEQLESCLVVLTNQGELHVISLPSIKMLVHYPCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTRWVVQPHCLVEPPLQMRSKSPSSPVHRDLPDGVPTEHRNFKGDSEGYENSARQVMEHALLNDESVLQEIQKSLEGDQTTFLENNLKTKPKAGNVLSNGD

LLGL2

Lethal(2) giant larvae protein homolog 2

1020 amino acids

Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity.

Belongs to the WD repeat L(2)GL family.

113.448 kDa

MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAAVGCSLSNGGAE

LLGL2

Lethal(2) giant larvae protein homolog 2

1019 amino acids

Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity (By similarity).

Belongs to the WD repeat L(2)GL family.

113.582 kDa

MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHRENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPMSSEAQQPEPLRSLVPYGPFPCKAITKILWLTTRQGLPFTIFQGGMPRASYGDRHCTSVIHDGQQTAFDFTSRVIDFTVLTEADPAAAFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNENLSAHGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAAHSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRMRRSRVSSRKRRPAGPPGEVQEGSVKAERPGLQNMELAPVQRKIEARSVEDSFTGFVRTLYFADTYLRDSSRHCPSLWAGTNGGTIYAFSLRVPPAERRMDETVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMPGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRVRNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSRNWRSHRAAVGCSLGNGGE