Protein
High-energy light unresponsive protein 1
Organism
Caenorhabditis elegans
Function
Photoreceptor for short wavelength (UV) light that mediates UV-light-induced avoidance behavior (PubMed:18687026, PubMed:20436480, PubMed:27863243). Directly senses and absorbs both UV-A and UV-B light with very high efficiency (PubMed:27863243). Absorption of UV-B but not UV-A light shows resistance to photobleaching (PubMed:27863243). In contrast to other photoreceptors, does not use a prosthetic chromophore to capture photons and only depends on its protein conformation (PubMed:27863243).
Similarity
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family.
Sequence
MPPPSSHSNIFHSTFKHTVKETMANAKKTMIAKILSSRNKWAICDRTLYPIYYLLLILGLNQSIRPNNSLLFRIYSWLVFCLLLFTTLRKFNQVGVRPNGTRENLQEFFANPRSMITLCNALIMLSGLLASLQLYTLGAKRLKPLKILCQFSLNVRTKQAERRQFMINTFLAVFSGLLALTMAATYAMSKWGYILYIVGTPNLDTETIFCVLLDSYALFVSRAAISALAILFYQHCSVIRRSIKHLINEMVPAEQDECPLPESSLQKIHDCQISYQRIFNGKAVIEEYYSFVLFYSYGVCIPIFCFLMFVGMSAQSICWSEVVSIVIWIVNAILVLLLFSLPAFMINEDGDRLVASSFRMYHETFHEERDLTVLSQMTFFTFQIHSTKLTLSACNYFYMDRSILLSLFSAILTYFLILWEFDIKNNQSLQNIANHTIHT