lin-23

Gene

lin-23

Protein

F-box/WD repeat-containing protein lin-23

Organism

Caenorhabditis elegans

Length

665 amino acids

Function

Functions cell autonomously to negatively regulate cell cycle progression. Required to restrain cell proliferation in response to developmental cues. Probably recognizes and binds to some proteins and promotes their ubiquitination and degradation (By similarity).

Mass

75.917 kDa

Sequence

MSSPHRASTTQQLADLSLTEGEHDEGKPLSIDYLQGHEGLIEEVLKWSEHEQLDFMDKIVHRLSHYQLGKVDNFIRPMLQRDFISNLPAHLVELILFNVNSDSLKSCEEVSTSWRCALARGQHWKKLIEKNVRSDSLWWGLSEKRQWDKFLNISRDMSVRRICEKFNYDVNIKRDKLDQLILMHVFYSKLYPKIIRDIHNIDNNWKRGNYKMTRINCQSENSKGVYCLQYDDDKIVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQYDNRVIISGSSDATVRVWDVETGECIKTLIHHCEAVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVSASGDRTIKVWSMDTLEFVRTLAGHRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAALDPRALSSEICLCSLVQHTGRVFRLQFDDFQIVSSSHDDTILIWDFLDAPPSGLPSSTNRATLPELPNQAAVARAQMLFEMAARREIERRDREVVEEPALRPRANAARRHNADIAAAAAAAEAARGAGDNDESSSEEDLDRVDQVNNPNVAGPAPPQPHNQNHRRRQPRPELPVRLMQEMAAFDNMRRQQNNMDHLGGGDVDEEMPDGGP

Protein

F-box/WD repeat-containing protein lin-23: lin-23