Protein
(4E)-oxalomesaconate Delta-isomerase
Organism
Novosphingobium sp. (strain KA1)
Function
Contributes to the degradation of lignin at the level of the protocatechuate 4,5-cleavage pathway. Catalyzes the isomerization of the double bond between C4 and C5 in (4E)-oxalomesaconate (OMA) to (3Z)-2-keto-4-carboxy-3-hexenedioate (KCH), where the double bond has migrated between C3 and C4 via a 1,3-allylic isomerization.
Similarity
Belongs to the PrpF family.
Sequence
MPRRDRNMDSAPCMWMRGGTSKGGYFLRADLPADTAARDAFLLAVMGSPDPRQIDGMGGADPLTSKVAVVSKSERPGIDVDYLFLQVFVDQAIVTDAQNCGNILAGVGPFAIERGLVAASGDETRVAIFMENTGQVAVATVRTPGGSVTYAGDAAIDGVPGTHAPIPTEFRDTAGSSCGALLPSGNAVDVVNGLPVTLIDNGMPCVVMKAADVGITGYEDRDSLDANAELKAKIEAIRLAVGELMNLGDVTEKSVPKMMLVAPPRDGGAVCVRSFIPHRAHATIGVLGAVSVATACLIPGSPAAEVAVVPEGARKTLSIEHPTGEMSCVLEVDDAGNVVSAALLRTARKLMDGVVFV