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lexA2

Gene
lexA2
Protein
LexA repressor 2
Organism
Nocardia farcinica (strain IFM 10152)
Length
243 amino acids
Function
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
Similarity
Belongs to the peptidase S24 family.
Mass
26.102 kDa
Sequence
MSRTDDTGEESGVAVDPALNGADLTVRQRKVLEVIRTSVSERGYPPSIREIGDAVGLTSTSSVAHQLRALERKGYLRRDPNRPRAVDVRGLDEAVRAVTALPGAALEEPDTLAEDTGRPTPTFVPVLGRIAAGGPILAEQAVEDVFPLPRELVGDGSLFLLRVVGQSMVDAAICDGDWVVVRQQNVAENGDIVAAMIDGEATVKTFKRTGKDVWLMPHNPLFEPIPGNDARILGKVVTVIRKI

Gene
lexA2
Protein
LexA repressor 2
Organism
Xanthomonas axonopodis pv. citri (strain 306)
Length
213 amino acids
Function
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
Similarity
Belongs to the peptidase S24 family.
Mass
23.24 kDa
Sequence
MDLTDTQQAILALIAERIDADGVPPSQTEIARAFGFKGIRAAQYHLEALEHAGAIRRVPGQARGIRLAGQGAQTRTAPVSEVARDDVLRLPVLGRVAAGLPIGADIGSDDFVVLDRVFFSPSPDYLLKVQGDSMRDEGIFNGDLIGVHRTRDARSGQIVVARIDEEITVKLLKIGKDRIRLLPRNPDYAPIEVLPDQDFAIEGLYCGLLRPNR

Gene
lexA2
Protein
LexA repressor 2
Organism
Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Length
213 amino acids
Function
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
Similarity
Belongs to the peptidase S24 family.
Mass
23.149 kDa
Sequence
MGLTDTQQAILALIAERIETDGVPPSQTEIARAFGFKGVRAAQYHLEALEQAGAIRRVPGQARGIRLAGAAAHARAAPAEEPVRDDVLRLPVLGRVAAGLPIGADIGSDDFVVLDRVFFSPSPDYLLKVQGDSMRDEGIFNGDLIGVHRTRDARSGQIVVARIDEEITVKLLKIGKDRIRLLPRNPDYAPIEVLPDQDFAIEGLYCGLLRPNR

Gene
lexA2
Protein
LexA repressor 2
Organism
Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)
Length
213 amino acids
Function
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
Similarity
Belongs to the peptidase S24 family.
Mass
23.173 kDa
Sequence
MDLTDTQQAILALIAERIDADGVPPSQTEIARAFGFKGVRAAQYHLEALEQAGAIRRVPGQARGIRLAGQGGQTRAAAVSEPVRDDVLRLPVLGRVAAGLPIGADIGSDDFVVLDRVFFSPSPDYLLKVQGDSMRDEGIFNGDLIGVHRTRDARSGQIVVARIDEEITVKLLKIGKDRIRLLPRNPDYAPIEVLPDQDFAIEGLYCGLLRPNR

Gene
lexA2
Protein
LexA repressor 2
Organism
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Length
203 amino acids
Function
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
Similarity
Belongs to the peptidase S24 family.
Mass
22.445 kDa
Sequence
METLTSRQRTVLEFITAHVDRHGYPPTMREIARHLNVNGTLGVAKHLEALARKGYLQREPGNSRGITLTGQTRHTPTVSLPVIGVVRAGVPQIATEEIEEHISIDQSLVKGGAFFLRVKGDSMINAAIIEGDLALVRPQQTAENRDIVVAMIDGEATLKRFYQGADHIRLQPENPNMAPIIVRSGVQEAWIIGKVVGIYRRMD

Gene
lexA2
Protein
LexA repressor 2
Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Length
202 amino acids
Function
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
Similarity
Belongs to the peptidase S24 family.
Mass
22.462 kDa
Sequence
MDTLTPKRRAIFEFIRERIAEHGQPPSLADIATRFGFASRSVARKHITALCQAGYIDVTPNQARGIRLAEPLRRPEILEIPVLGQVAAGAPIGPDLGIHEQLLLDPSLFRRTPDYLLKVRGDSMIDDGIFDGDLVGILQQADARDGQIVVARLDGEVTIKRLQRQGGTYRLLPRNPAYAPIDVQPEQDFFIEGVFCGLLRRD

Gene
lexA2
Protein
LexA repressor 2
Organism
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Length
202 amino acids
Function
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
Similarity
Belongs to the peptidase S24 family.
Mass
22.181 kDa
Sequence
MSTLSPRRSAILTFIRDRIAQQGQSPSLAEISEAFGFASRSVARKHIVALTEAGLIEVVAHQARGIRLLNSEPRPELLEIPVLGRVAAGAPIGPDLDIHTTLHLDRSTFTRVPDYLLRVQGDSMIEDGILDGDLVGVHRNPQASDGQIVVARLEGEVTIKRLQHRGDQLHLLPRNPAYQPIIVTPDQDFAIEGVFCGLVRRE