let-60

Gene

let-60

Protein

Ras protein let-60

Organism

Caenorhabditis elegans

Length

184 amino acids

Function

The level of let-60 controls the switch between vulval and hypodermal cell fates during C.elegans vulval induction (PubMed:2257629, PubMed:2123303, PubMed:24929033, PubMed:28135265). May stimulate the guanine nucleotide exchange factor (GEF) activity of rap-1 (PubMed:10608844).

Similarity

Belongs to the small GTPase superfamily. Ras family.

Mass

20.983 kDa

Sequence

MTEYKLVVVGDGGVGKSALTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAVNEAKSFENVANYREQIRRVKDSDDVPMVLVGNKCDLSSRSVDFRTVSETAKGYGIPNVDTSAKTRMGVDEAFYTLVREIRKHRERHDNNKPQKKKKCQIM

Protein

Ras protein let-60: let-60