Protein
Small toxic polypeptide LdrD
Organism
Escherichia coli (strain K12)
Function
Toxic component of a type I toxin-antitoxin (TA) system. Overexpression causes rapid cell killing and nucleoid condensation of the host cell (PubMed:12123448). Overexpression induces stress-response and a number of membrane protein genes. May inhibit ATP synthesis due to its insertion in the cell inner membrane (By similarity).
Similarity
Belongs to the Ldr toxic peptide family.
Sequence
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK