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laat-1

Gene
laat-1
Protein
Lysosomal amino acid transporter 1
Organism
Caenorhabditis elegans
Length
311 amino acids
Function
Amino acid transporter that specifically mediates the pH-dependent export of the cationic amino acids arginine, histidine and lysine from lysosomes (PubMed:22822152). May play a role in the degradation of autophagic substrates in autolysosomes by regulating lysosome function (PubMed:25124690).
Similarity
Belongs to the laat-1 family.
Mass
34.96 kDa
Sequence
MKTGGLSDFADFGEEDANCTQGIQWIKDVFTDCVDTDLKLLGFIIGLISLALWLIPLFPQLWQNYKTKKCEGLSLAFLFFWLVGDTCNMLGAILTNQQPIQKIIGVYYIIQDLVLWTQYGYYLKIYNRPTTSSARSNTIVVPVLALASVGSFFVFESALPPVGDHRVKRSFLESLNHQEGLPLEGILKMWPIFTSYTDMLGYIIGSMAAVCYFGGRIPQIIKNYRHSSCEGLSLTMFYIIVAANFTYGISVLLATTSWLYLLRHLPWLAGSLGCCCFDAVIISQYYLYRPKTPLAEDTERAGLLNSQDDSD