laat-1

Gene

laat-1

Protein

Lysosomal amino acid transporter 1

Organism

Caenorhabditis elegans

Length

311 amino acids

Function

Amino acid transporter that specifically mediates the pH-dependent export of the cationic amino acids arginine, histidine and lysine from lysosomes (PubMed:22822152). May play a role in the degradation of autophagic substrates in autolysosomes by regulating lysosome function (PubMed:25124690).

Similarity

Belongs to the laat-1 family.

Mass

34.96 kDa

Sequence

MKTGGLSDFADFGEEDANCTQGIQWIKDVFTDCVDTDLKLLGFIIGLISLALWLIPLFPQLWQNYKTKKCEGLSLAFLFFWLVGDTCNMLGAILTNQQPIQKIIGVYYIIQDLVLWTQYGYYLKIYNRPTTSSARSNTIVVPVLALASVGSFFVFESALPPVGDHRVKRSFLESLNHQEGLPLEGILKMWPIFTSYTDMLGYIIGSMAAVCYFGGRIPQIIKNYRHSSCEGLSLTMFYIIVAANFTYGISVLLATTSWLYLLRHLPWLAGSLGCCCFDAVIISQYYLYRPKTPLAEDTERAGLLNSQDDSD

Protein

Lysosomal amino acid transporter 1: laat-1