Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Sequence
MSTAAVQDARKQAEALDNEDSIAFVRDEFNIPTKAQIASSRLADSHPAALPASEDDAKCIYLCGNSLGVQPKRTVTRLNQYLTTWATQGVQGHFKPLEESPLPTWLDADAKAAELIAPVVGANVSEVAVMQTLTANIHLLMSAFYRPDINGRHKIILENKAFPSDHFAVETQIRHHSLSTEKSMVLIESSSKDNIISTEEVLSVISAHADTTALLLLPGIQYYTGQLLDIPAITAFAHKHGIFVIWDLAHAVGNVPLYLHDWGVDAAAWCSYKYLNGGPGCIGGLFVHTNNSVVTKEITDEKPEEGYNNRLAGWWGNDKKTRFVMANKFHPVAGAAGFQLSNPSILDITSLSASLEIFQEAGGMEALRSKSLKLTSFLEATLGHMKEEDRAHFRIITPSKSEERGAQLSLMLSDGLLDTVMKELEARGVIVDERKPNVIRVAPAPLYNTFKDCVLFVEAFSAALEVAKQHAL