kin-29

Serine/threonine-protein kinase kin-29

822 amino acids

Regulates chemoreceptor expression by phosphorylating the hda-4 class II histone deacetylase (HDAC) and inhibiting the gene repression functions of hda-4 and the mef-2 transcription factor, enabling the correct sensing and transduction of food signals. Role in determining body size, the dauer decision and serotonin-mediated egg laying. May modulate the Sma/Mab pathway and regulates development in the later larval stages.

Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

91.365 kDa

MAAPRRRMGLEKIGLYDVGRAIGKGNFATVRIARHKIAKTKVAIKSIDVSALDRENLIKLEREVKIVKVIDHPHIVKSYEIMRVDNMLYIVSEYCSSGELYETLIEKGRVAENVARKWFSETASAVAYLHSQGIVHRDLKAENILLGKNSNIKIIDFGFSNFQTGDQLLNTWCGSPPYAAPELLLGNSYDGMKADIWSMGVLLYILVAGGFPFPSDSVNKLKRSVLSGLVKIPYWVSVECADFIRKMLVLNPGKRYTIQNVLQHRWMHIRDDVQKNQAAQLLEAIPSSSIEIRQQSTKLNPTIMMFMQQHGKWSEEQIIDAVLGRDFESPIFATYELLADKVKKGTLEGTGEEFPRRGSRGSILSGKANVDEQPLTPTISAHQLAQLNLSSPDCDSDDSSNSDLCDDSPMSSMGPMNHERQFGTPHGLDIIGNRFENRRHTLCASEQLLSPNMMGQFPPPNLLLNNFSMNPPLGFPPMPEGQAAEFPLPSLHPAFATIPIADLSKMLPVPKSERRASAGETLLPTNFDLTQHLANLPAPPISFPTVEEEGKSYLSKYGGKRNTVHCLGNQLGGGIQNPIPRYQRTPYTKAPPAERRSSWASPSLSAQQQNHLEKLFKQALQTNNDMTRLHKEFKGLSHGCAQSQITNEGSSLACPQISITDEYNRQHNIAPSASSFDPVSIFQKNAQEVVFGQRPATAIGFSSTSFSGMSTPEQTTRSIDDRVRSIVCTLPFTEVIDELKASLNILKIPFSESHEMVYEPQVTEMRRLSLPSGVEIGVAVLPPEHKAHVEFAIINNDSPTSEYLCDQLICRLRMIDPSWSSE

kin-29

Serine/threonine-protein kinase kin-29

813 amino acids

Regulates chemoreceptor expression by phosphorylating the hda-4 class II histone deacetylase (HDAC) and inhibiting the gene repression functions of hda-4 and the mef-2 transcription factor, enabling the correct sensing and transduction of food signals. Role in determining body size, the dauer decision and serotonin-mediated egg laying. May modulate the Sma/Mab pathway and regulates development in the later larval stages (By similarity).

Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

90.497 kDa

MAAAAPKRRMGLEKIGLYDVGRAIGKGNFATVRIARHRIAKTKVAVKSIDVSKLDKENLIKLEREVKIVTMIDHPHIVKCYEIMRVDNMLYIVSEYCSTGELYATLMGKGRVTEDIARKWFTETAAAVSYLHNKGIVHRDLKTENILLGKDSKIKLIDFGFSNFQTPDQLLNTWCGSPPYAAPELLLGNSYDGMKADIWSMGVLLYILVTGGFPFGSESVNDLKRSVLSGVVKIPYWVSVECADFIRKMLVLNPTKRMTIQNVLAHRWMHIRNDVKKQVQNLESSIRPTPSKLNPTIMMFMQQHGKWTEEQIIDAVLGRNFESPIFATYELLADKVKIGSLEGTGEEYPRRGSRGSILSGRANVDEQPLTPTISAHQLAQLNLSSPDCDSDDSSNSDLCDESPLSSLEPNHKQFTLPRGLDLMGNRFENRRHTLCASEQLLSPNLMGQFPPPNLLLNNFTMSPLGFPPMPEGQAAEFPFPSLHPALGAFPTTDLSKMLPVPKSERRASAGETLLPTNFDLQQHLANLSANPVSFPTVEEEGRSYLAKYGGKRNTVHCLGNQIGGGVQNPIPRYQRTPYAKAPPAERRSSWASPSLSQQQQSHLEKIFKDALQTNNDISRLHKEFKNLSHGCAQSQITNEGSSLACPQISITDEYNRQHNIAPSASSFDPVSIFQKNAQEVVFGQRPATAIGFSSTSFSGMSTPEQTTRSMDDRVRSIVCTLPFAEVVEELKSSLNILKIPFAETQEMVYEPQVTEMRRLSLPSGVEIGVAVLPPEHKSHVEFAIINNDSPTSEILCDQLICRLRMIDPNWSSE