kdgA

2-dehydro-3-deoxy-D-gluconate/2-dehydro-3-deoxy-phosphogluconate aldolase

306 amino acids

Involved in the degradation of glucose via the Entner-Doudoroff pathway. Catalyzes the reversible cleavage of 2-keto-3-deoxy-6-phosphogluconate (KDPG) and 2-keto-3-deoxygluconate (KDG) forming pyruvate and glyceraldehyde 3-phosphate or glyceraldehyde, respectively. It is not able to use 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) and 2-keto-3-deoxygalactonate (KDGal) as substrate.

Belongs to the DapA family. KDPG aldolase subfamily.

33.287 kDa

MSHPLIPFRANFLRAPRVLSMEIVAPVITTFRGGRLDPELFANHVKNITSKGVDVVFVAGTTGLGPALSLQEKMELTDAATSAARRVIVQVASLNADEAIALAKYAESRGAEAVASLPPYYFPRLSERQIAKYFRDLCSAVSIPVFLYNYPAAVGRDVDARAAKELGCIRGVKDTNESLAHTLAYKRYLPQARVYNGSDSLVFASFAVRLDGVVASSANYLPELLAGIRDAVAAGDIERARSLQFLLDEIVESARHIGYAAAVYELVEIFQGYEAGEPRGPVYPLDPEEKAWLRAAVAKAKSQLRL

kdgA

2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase

290 amino acids

Involved in the degradation of glucose and galactose via the Entner-Doudoroff pathway. Catalyzes the reversible cleavage of 2-keto-3-deoxy-6-phosphogluconate (KDPG) and 2-keto-3-deoxygluconate (KDG) forming pyruvate and glyceraldehyde 3-phosphate or glyceraldehyde, respectively. It is also able to catalyze the reversible cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) and 2-keto-3-deoxygalactonate (KDGal).

Belongs to the DapA family. KDPG aldolase subfamily.

32.598 kDa

MDIVTPILTPFTKEGKIDVEKLKAHAKFLIDNGIDLLFVNGTTGLGPALSKEEKLTTLKTIYDVTNKVIFQVGSLNINDVIDLVKASKDFDIVGIASYPPFYFPRLPEKFLLKYFTTIANYSPHSLYIYNYPLATGYDISAKIVYQMKDLITGLKDTNQDLSHSLEYKILMPNLKVYNGSDSLVFYSLTSLDGSVTAASNYLPHVMKKMKEHITSGQVSKAIELQKLINKALDISRKYGQLSAIYYLVKEFLGYDVGYPRGPIFPLEEDEVKALLSEIQPVKKEIERAVS