KAP114

Importin subunit beta-5

1004 amino acids

Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. Serves a receptor for nuclear localization signals. Mediates the nuclear import of TATA-binding protein (TBP) and of histones H2A and H2B.

Belongs to the importin beta family.

113.921 kDa

MDINELIIGAQSADKHTREVAETQLLQWCDSDASQVFKALANVALQHEASLESRQFALLSLRKLITMYWSPGFESYRSTSNVEIDVKDFIREVLLKLCLNDNENTKIKNGASYCIVQISAVDFPDQWPQLLTVIYDAISHQHSLNAMSLLNEIYDDVVSEEMFFEGGIGLATMEIVFKVLNTETSTLIAKIAALKLLKACLLQMSSHNEYDEASRKSFVSQCLATSLQILGQLLTLNFGNVDVISQLKFKSIIYENLVFIKNDFSRKHFSSELQKQFKIMAIQDLENVTHINANVETTESEPLLETVHDCSIYIVEFLTSVCTLQFSVEEMNKIITSLTILCQLSSETREIWTSDFNTFVSKETGLAASYNVRDQANEFFTSLPNPQLSLIFKVVSNDIEHSTCNYSTLESLLYLLQCILLNDDEITGENIDQSLQILIKTLENILVSQEIPELILARAILTIPRVLDKFIDALPDIKPLTSAFLAKSLNLALKSDKELIKSATLIAFTYYCYFAELDSVLGPEVCSETQEKVIRIINQVSSDAEEDTNGALMEVLSQVISYNPKEPHSRKEILQAEFHLVFTISSEDPANVQVVVQSQECLEKLLDNINMDNYKNYIELCLPSFINVLDSNNANNYRYSPLLSLVLEFITVFLKKKPNDGFLPDEINQYLFEPLAKVLAFSTEDETLQLATEAFSYLIFNTDTRAMEPRLMDIMKVLERLLSLEVSDSAAMNVGPLVVAIFTRFSKEIQPLIGRILEAVVVRLIKTQNISTEQNLLSVLCFLTCNDPKQTVDFLSSFQIDNTDALTLVMRKWIEAFEVIRGEKRIKENIVALSNLFFLNDKRLQKVVVNGNLIPYEGDLIITRSMAKKMPDRYVQVPLYTKIIKLFVSELSFQSKQPNPEQLITSDIKQEVVNANKDDDNDDWEDVDDVLDYDKLKEYIDDDVDEEADDDSDDITGLMDVKESVVQLLVRFFKEVASKDVSGFHCIYETLSDSERKVLSEALL

kap114

Importin subunit beta-5

993 amino acids

Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. Serves a receptor for nuclear localization signals. Mediates the nuclear import of TATA-binding protein (TBP) and of histones H2A and H2B (By similarity).

111.864 kDa

MVESKIIKLLEQVQSADPNSRIQAELGLRDLEKYHDFAAKLTDIASSGASVPLRQGSLIYLQRYIVHHWSPLFEQFQDGPIPDENVKKHVRETLLHLLVSLDNFTLIKAVAYAVSLIANVDYPDEWPEVVPAVLHLLQSTNENSINASLDVLDELVDESLVEEQFFIIAPQLASILYQFIFSAPPNDSMRMLQARGIKLFRSCLELIEIYKETKAEHVRVFLEQILPPWMDMFSHKFEVSLVDDRQVILPDSCGYFCIMGEIAMTLTKLRELFPSKLTPYVVTFVELVWNIIEKLLDPYIREVVFSDGLDDSAFGDKYPIRYLVELLLFVSVALQSKFVQNLFVSNTVPVPPLPPCIPLLVQYTQLPKHQIEVYESDVSEYIANEFSMDFASDTVRGAAISVLSAFEEHTTLPIQQSLREMSATYILNNEINWIYQEALLYACCSVDAASDDTYDDYLDPIYEAIKVRIDYSDAPILLLSRFFLFIGYFSESTVVASQFFQIIMNNLVNALQVDTVQYAAMKAIERFCSVGKVKPILSLQPMILEVLSQYASKSSDEALVLLVEAISSAVKLDCAKAAELGNSVIPLLFNLVATNASDPYICGIIEDTFEDIIHAANNYESMCEITLPELLQVLNQEDPIMVNIGATLLSCLIRAGPSPLPNGFVGYVLPPVYKITQIHSGDTELLQLSQEILKGLLEKDTPQLLETEISGSSGFQYILFILHQLLDKESDDSACFLVGPILLELADHASQMVDLQSILLSCIKRLAIAEQPRFIQSIIYVFAKLIVKDSLGMMHFLTSSLLNEQGLTAFEVLMTVWCDNFVYFSNFKNISIICIAMTKIYSFDSPLLDSVQVKGELISHSNRIITRSQSKLHPEEYSYVSVGEKILRLLSEEFVSLSKDAIVEEVSDDGADDWDDGPISAETFGLSANDVNELSKDEFSGVDNSEDEDNTDLQFYLLEFFKEAMKSNLHNINEVVFRLPQEEQDALVQIKEK