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irk-1

Gene
irk-1
Protein
Inward rectifier potassium channel irk-1
Organism
Caenorhabditis elegans
Length
544 amino acids
Function
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Required for modulation of the activity of the hermaphrodite-specific neurons (HSNs) by the G-protein coupled neuropeptide receptor egl-6 which in turn controls egg-laying behavior.
Similarity
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
Mass
61.338 kDa
Sequence
MTLSVPDCAEMNRIRMSNHRKMSLGSAPLIANGRPSPPPRRTSLAESIRTLAFTARRNSSPLYRKSTKKLKKSRLVGKNGICNVYNTNVPKKDRQYLRDIFTTMIDVKWRWMLMLFASAFVLSWSIFGTTYYLIALVHGDLSLPTPVNHTACVMNLDSVYSSFLFAVETHHTIGYGHRYITTECYLAGAIVCLQAICALLLQSFMVGIVFAKMARPKKRAETIIFSDKAVICLRDGQLCFLCRVGDMRNTHLVEAHVRLQFITDRETNEGEIEPLHQFEMKVGPSIADDDRLFLVWPTTLCHVIDSRSPLYNYNQQTLMSAQFEIIVLLEGIVESTGMTAQAKTSYLPSEVLWGHRFRKLVTYQRSNGSYQIDYDLFHSTYPVRTPAMSPAEFYSSKPNLKDYYCHDSHEHKLEDNRSSDSTPLPSPSPYSYPSTPLNHFQSSSNSPVFSNNHSKFNTEAVTCEAGMLCPPTIVVQCPSTCASPNHMRRTRNQMDKSRTSSSCDLTRPSTALSDLEEECSDSGSPTKCQSPPVVPIHIEIVSET