ipuC

Glutamate--isopropylamine ligase

459 amino acids

Involved in the degradation of isopropylamine, which is a constituent of the herbicides atrazine. Catalyzes the ATP-dependent formation of gamma-glutamyl-isopropylamide from isopropylamine and L-glutamate. It can also use aminoalkanes, amino-alcohols (L-alaninol and D-alaninol) and amino-esters as substrates.

Belongs to the glutamine synthetase family.

50.586 kDa

MSEENKKQILKVRDFIEKHNIDTIRLGAVDIDGVWRGKQVGAEYFLNKAALDGTQISNILFGWDVADHLVDGLEFTGWDSGYPDIALIPDLSTLSLVPWQEKTASVLCDIQHLNGEPLNLSPRNLLRKAIEKAEQLGYKCYAAYEFEFYLLNDSIASISADQWRSINPVEKSGHCYSMLHHSSSSDIMGEVRKYMRDAGIVLEATNSEHGPGQYEINIKYDDALKAADDAIFVKNGIKEIAAKHGMTATFMAKPSAEWSGSSGHVHMSLSDLAGTPVFANPENPGALSEVGYNFLAGMVALAREMSAIYLPNINSYKRTAGASWAGGNSSWGFDNRTVSHRAITSAGSAARVENRIPGADTNPYLVIAASLLSGLYGIENKLKPKDPILGNAYKVSPELARPLAASLEEAAGIFRESEMARVIFPNEFVEHYAQMKVWEIKQSNSFVNNWELARYLDII