Function
Virulence factor that eliminates N-myristoyl protein modifications in infected host cells. Acts as a cysteine protease that cleaves the peptide bond between N-myristoylated Gly-2 and Asn-3 of human ARF1, leading to the elimination of the myristoyl group and alteration of protein trafficking in host cell. Could also cleave an array of N-myristoylated host proteins involved in cellular growth, signal transduction, autophagasome maturation and organelle function.