Protein
Inactive atromentin synthetase invA6
Organism
Paxillus involutus
Function
Inactive atromentin synthetase homolog. Does not accept 4-hydroxyphenylpyruvate (4-HPP) as substrate. Both the adenylation (A) and the thioesterase (TE) domain of the invA6 enzyme are inactive.
Similarity
Belongs to the ATP-dependent AMP-binding enzyme family.
Sequence
MAPVAITPATLVGHDLKSSRASERATELSPVTLLDIFSRAVSLYPKHELSFVTSSAHDSSVQTRSFSEFDQYARALAWAMLAWGKPTGSVIVVYFTEHEDNMAAVWACLLAGHVPCLQPALSEQQAHKEGHVAHIKNLFSSATWLTNESGAEQVHSITGLDIRLLSELKARAETVGADFHAHQPNPDDEAILFLTSGSTGFSKVVVHTHRTILAACNAKGQSYGLTSESKTMNWVGFDHVAGSLEMHIAPLLYGASQLHVHVSAILADPSRFLRLIEEKSIQLAFAPNFLLAKLTRDLEKCSDLFGKFDLSSIKRINSGGEAVVSSTAQAFARTLKNFAKDGNASFVISAGFGTTETCAGCIYDPIDVLFTPPSYEFLELGTPLTGCEMCIVNPQDGVTPRPDGESGELQVRGPMVFVRYYNDPKATTSSFIEGVWYRTGDVGIIEKGKMRLNGRIKDTVIVHGVSYGIAELETYLQTVEGVTHSFLAAAPHRDPGQETEGFVIFYSPTFELDSEDAPAKLYATHRALRDVSVKMITLPPQQIIPIPLNQMEKTTLGKLSRVCLVNLFKQGELANHIARAEELLSIARGATFIAPSTETEKTLGRLYAEIFNLRVSDVSASDNFFELGGNSIDVIKLKREAESLFELPEILTVQILKHPVISSLAKYVDSLVSKDGSQEEYDPVVPLQLTSNKTPIFMVHPGIGEVLAYVDLAKYFQNERPFFALRVRGFEGQPLFTSMDEMASSYAAGAKRTQPHGPYAIAGYSYGGVVAFEVAKRLESMGDEVKFIGLVDIPPHIADRMHDWTSGMLNLSHLLGLMSKQDADNLAPSLRTLTRKEQFEVLWKLSPPERLTELQLTPEKHENWVYIAGGLSECGMTYQPGGSVSVLDVFYAMPPHDTKEDWLNQHLRRWADFCRSEPSFTNVPGHHDTLMDFDHVSGFQKIFRDALEARGL