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ins-6

Gene
ins-6
Protein
Probable insulin-like peptide beta-type 5
Organism
Caenorhabditis elegans
Length
112 amino acids
Function
Probable insulin-like peptide which negatively regulates synapse development at the neuromuscular junctions (PubMed:23665919). Probably acts as a daf-2/InsR agonist ligand to prevent dauer formation under optimal environmental conditions (PubMed:24671950). Acts on AWC sensory neurons to regulate high salt chemotaxis responses (PubMed:24013594).
Similarity
Belongs to the insulin family.
Mass
12.273 kDa
Sequence
MNSVFTIIFVLCALQVAASFRQSFGPSMSEESASMQLLRELQHNMMESAHRPMPRARRVPAPGETRACGRKLISLVMAVCGDLCNPQEGKDIATECCGNQCSDDYIRSACCP