Organism
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Function
Contributes to systemic listeriosis in mice by decreasing host IL-6 cytokine production and thus evasion of the host immune response. Does not contribute to invasion of the host intestinal tissue.
Similarity
Belongs to the internalin family.
Sequence
MKKRWNSVFKLVLMVTAILGLSLYVTTSQGVEVRAESITQPTAINVIFPDPALANAIKIAAGKSNVTDTVTQADLDGITTLSAFGTGVTTIEGVQYLNNLIGLELKDNQITDLTPLKNLTKITELELSGNPLKNVSAIAGLQSIKTLDLTSTQITDVTPLAGLSNLQVLYLDLNQITNISPLAGLTNLQYLSIGNAQVSDLTPLANLSKLTTLKADDNKISDISPLASLPNLIEVHLKNNQISDVSPLANTSNLFIVTLTNQTITNQPVFYQNNLVVPNVVKGPSGAPIAPATISDNGTYASPNLTWNLTSFINNVSYTFNQSVTFKNTTVPFSGTVTQPLTEAYTAVFDVDGKQTSVTVGANELIKEPTAPTKEGYTFTGWYDAKTGGTKWDFATDKMPAEDITLYAQFTINSYTATFDIDGKLTTQKVTYQSLLEEPVAPTKDGYTFTGWYDAKTGGTKWDFATGKMPAGNITLYAQFTKNDNPNPDDPTTNTPTGNGDGTSNPSNSGGNTTLPTAGDENTMLPIFIGVFLLGTATLILRKTIKVK