ind1

Indolepyruvate C-methyltransferase

329 amino acids

Involved in the biosynthesis of the antibiotic indolmycin, an inhibitor of the bacterial tryptophan-tRNA synthetases. Catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to position 3 of the aliphatic side chain of (indol-3-yl)pyruvate to yield 3-methylindolepyruvate.

Belongs to the methyltransferase superfamily.

35.84 kDa

MTRTDFAQSAVASIFTGAIASHAAVLADDLGLFDALAKGKLRNRDLDRSPWLRNRIRISGALEALCRVGAVQRCTDGYELTDVGTELAGQVPVFRLWLGGYASVLAGQISIGADPATGVHGGIVAESSGAIGARYLDETIVNLLESLRPEGRICDIGCGTGARLLRVCRRVNQPGIGYDLSAKAVEAARETVDEARRIGVDIDVRQGDATALTQDHPDVDIVTQAFMTHHIAPDEYCAAVLRSYRSRFPRARYLVIFDTVPSQDSEEPEIFAPGFDYIHALQNMEPRSRGAARRMFTEAGYICREEVELAVPNSYAWVLEMRDREGPAS

IND1

Iron-sulfur protein IND1

312 amino acids

Required for the effective assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Probably facilitates the assembly of Fe-S cofactors and subunits of complex I.

Belongs to the Mrp/NBP35 ATP-binding proteins family.

33.167 kDa

MRGFRLIAPIQRSIAIISRLQPITANFHSSPALRSHENPLGIPKSPASAPRIPRKTTRRPEPIAGVKKTIVVSSAKGGVGKSTVSVNTALSLAKRGLRVGLLDVDIFGPSIPTMFGLSGEPRMTHEGKLIPMSKFGIQVMSMGFLVDPNKAVAWRGLLVQKALEQLLQDVDWGTLDVLVMDLPPGTGDVQLTIAQTVKIDGAIIVSTPQDVALVDVVRGLDLFEKTYTKVLGLVQNMSVFVCPNCNHETHIFGVDGAVSKAKSRGLGVLGNVPLDPQICSQSDKGVPVAVSGGVQAKYYDKIAEGVAEQLGV