impdh

Inosine-5'-monophosphate dehydrogenase

515 amino acids

Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.

Belongs to the IMPDH/GMPR family.

56.311 kDa

MEKINKILQGTNSEYKSEWFVDGFDCFELFQQRHGYTYDDLIMLPGHINFSADDVSLKTKLTKNISLNAPLVSSPMDTVTEHLMAINMALLGGIGIIHYNNTVEEQVVEVKKVKRFKNGFITDPIVLSPTHKLSDVDMIKQKYGFSGIPITDTGRIGGKLVGIVTSRDTDFIKDRSTTLSEVMTTDLITGQQNCTLEEANSILKSCKKGKLPIVNDKGELVALASRDDLVKNRDFPMATKDHENKKLLVGAALGTRETDKERLAALSDAGVDVVILDSSQGDSTYQREMIRFIKRNYPKIDVIGGNVVTTSQCESLIQAGVDGLRVGMGVGSICTTQEVMACGRPQATAVFKCALYSSQYNVPIIADGGIRTIGHIIKGLSLGASSVMMGSMLAGTEEAPGDYFYKDGMRLKKYRGMGSLEAMVKGGDQRYFSETDKIKVAQGVSGSVVDKGSVKKFVPYLIQGIKHGLQDLGCNSVTNLRESVYGGKVRFEVRTAAAQVEGSVHSLFSYEKHFI

IMPDH

Inosine-5'-monophosphate dehydrogenase

503 amino acids

Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism.

Belongs to the IMPDH/GMPR family.

55.473 kDa

MAKYYNEPCHTFNEYLLIPGLSTVDCIPSNVNLSTPLVKFQKGQQSEINLKIPLVSAIMQSVSGEKMAIALAREGGISFIFGSQSIESQAAMVHAVKNFKAGFVVSDSNVKPDQTFADVLAISQRTTHNTVAVTDDGTPHGVLLGLVTQRDYPIDLTQTETKVSDMMTPFSKLVTAHQDTKLSEANKIIWEKKLNALPIIDDDQHLRYIVFRKDYDRSQVCHNELVDSQKRYLVGAGINTRDFRERVPALVEAGADVLCIDSSDGFSEWQKITIGWIREKYGDKVKVGAGNIVDGEGFRYLADAGADFIKIGIGGGSICITREQKGIGRGQATAVIDVVAERNKYFEETGIYIPVCSDGGIVYDYHMTLALAMGADFIMLGRYFARFEESPTRKVTINGSVMKEYWGEGSSRARNWQRYDLGGKQKLSFEEGVDSYVPYAGKLKDNVEASLNKVKSTMCNCGALTIPQLQSKAKITLVSSVSIVEGGAHDVIVKDRINDYHPK

IMPDH

Inosine-5'-monophosphate dehydrogenase 1

503 amino acids

Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.

Belongs to the IMPDH/GMPR family.

54.194 kDa

MSTLEDGFPADKLFAQGYSYTYDDVIFLPHFIDFSTDAVSLSTRLSRRVPLSIPCVSSPMDTVSESHMAAAMASLGGIGIVHYNCGIAAQASIIRQAKSLKHPIASDAGVKFPEYEITSLDAFGPSSFVFVEQTGTMTTPKLLGYVTKSQWKRMNYEQREMKIYDYMKSCDSSDYCVPWEIDFEKLEFVLEDKQKGFVVLERDGETVNVVTKDDIQRVKGYPKSGPGTVGPDGEWMVGAAIGTRESDKERLEHLVNVGVNAVVLDSSQGNSIYQLEMIKYVKKTYPELDVIGGNVVTMYQAQNLIQAGVDGLRVGMGSGSICTTQEVCAVGRGQATAVYKVCSIAAQSGIPVIADGGISNSGHIVKALVLGASTVMMGSFLAGSTEAPGGYEYTNGKRIKKYRGMGSLEAMTKGSDQRYLGDQTKLKIAQGVVGAVADKGSVLKLIPYTMHAVKQGFQDLGASSLQSAHGLLRSNILRLEARTGAAQVEGGVHGLVSYEKKSF

impdh

Inosine-5'-monophosphate dehydrogenase

502 amino acids

Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.

Belongs to the IMPDH/GMPR family.

53.45 kDa

MDFTPPPIEDGFTAEKLFSQGFSYTYDDVIFLPHYIDFAADAVDLSTRLTRRLPLAVPLVASPMDTVSESAMASAMASLGGIAIVHSNVPAAAQASLVRAAKSRRVPILSEPAFAAPSAVIEHEDDFAASPFLLVTDIGAAGGKLLGYVAKRDWTNQKDKSLRVGDYMAPPPRRAPWNADLNKIHEIMENEKSGAVALERDGEVVDLVVREEVERVKGYPKLAAPATVGPDGEFMVGAAMGTREDDKERLKHLVKAGVNVVVLDSSQGNSIYQLEMVKYVKSVYPELDVIGGNVVTMYQAENLIQAGVDGLRVGMGSGSICTTQEVCAVGRGQATAVYKVSSIAYKSGVPVIADGGISNSGHIVKALSLGASTAMMGSFLAGSHEAPGAYVYQNGQRVKKYRGMGSLEAMTKGSDARYLGDTAKLKIAQGVVGAVKDKGSVLNFIPYTLQAVRQGFQDIGASSLQSAHDLLRSRVLRLEVRTGAAQVEGGVHGLVSYEKKYY