Protein
Insulin-like growth factor II-B
Function
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Promotes anterior neural development. Acts as a ligand for integrin which is required for IGF2 signaling.
Similarity
Belongs to the insulin family.
Sequence
MEQLSCKHRSSSMEAEAQLCRQTESRSTQLPRMSVMRHLFLLSITFLVYTLDSAKAYRPTETLCGGELVDTLQFVCGDRGFYFSTNNGRSNRRSNRGIVEECCFRSCDLELLETYCAKPSKNERDVSTAPATAIPPMNKQDLYHKHHHTKSSKYDIWQRKSIHRLRRGVPAIVRARQYRLLMQKAEESEQALLHRPLTTLPITRPLHLQQTSEPSHN