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igf2-a

Gene
igf2-a
Protein
Insulin-like growth factor II-A
Organism
Xenopus laevis
Length
217 amino acids
Function
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Promotes anterior neural development (PubMed:11709186). Acts as a ligand for integrin which is required for IGF2 signaling (By similarity).
Similarity
Belongs to the insulin family.
Mass
24.874 kDa
Sequence
MEQLSCKHRSSSVEAEAQLCRQTESRSTQLPRMSVMRHLFLLSITFLVYTLDSAKAYRATETLCGGELVDTLQFVCGDRGFYFSTNNGRSNRRPNRGIVDVCCFKSCDLELLETYCAKPTKNERDVSTAPATAIPPLSKQDLYHKHHHTKSSKYDIWQRKSIHRLRRGVPAIVRARQYRLLMEKAEEAEQALSHRPLTTLPITRPLRLQQASEPSHN