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iff-2

Gene
iff-2
Protein
Eukaryotic translation initiation factor 5A-2
Organism
Caenorhabditis elegans
Length
161 amino acids
Function
mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity). Acts in somatic tissues and its function in the soma is essential for normal growth and reproduction.
Similarity
Belongs to the eIF-5A family.
Mass
17.953 kDa
Sequence
MSDDHHDDEHFHTGDSGAAATFPKQCSALRKNEHVMIKGRPCKIVEMSTSKTGKHGHAKVHMVAIDIFTSKKLEDICPSTHNMDVPVVKRREYLLMAIDDGYCSLMDPESCEQKDDLKLPDTELGQQIRDAYEKDEGSVLVQVVSAIGEEAILGWKVSTKE