IBA57

Putative transferase CAF17, mitochondrial

497 amino acids

Required for lysine and glutamate prototrophy and mitochondrial genome maintenance. Has a role in the maturation of mitochondrial aconitase-type and radical-SAM Fe/S proteins biotin synthase and lipoic acid synthase.

Belongs to the GcvT family. CAF17 subfamily.

57.055 kDa

MFISRRCRIKGFTLKNLLWFRSSSTRFVSTESPDASAITKPDGIFNYSLLENRTYIRIRGPDTVKFLNGLVTSKLLPHFIKKNLTTVEENEVPTEEGTTKVDPIIPVPEFDARLGNWGLYNEKGIQGPYISRFGLYSAFLNGKGKLITDTIIYPTPVTVSEQISNYPEYLLELHGNVVDKILHVLQTHKLANKIKFEKIDHSSLKTWDVEVQFPNLPKDIENPWFDNLLDPMALPKNSIDANNFAVNVLNSLFNSDPRILGIYVERRTESMSRHYSTFPQSFRVVTSEQVDDLSKLFNFNVFDFPFQVNKKASVQVREIRFQKGLIDSTEDYISETLLPLELNFDFFPNTISTNKGCYVGQELTARTYATGILRKRLVPVKLDNYQLLDTDPERKYAEFHIDNVVEKSLAENEPTLNPFTNKPPERTKRKQRPAGLLISNEGLYGVALLRTEHFSAAFSSDEPVEFYITTTKGENIKITPQKPFWFSDWKNNNGPHK

Iba57

Putative transferase CAF17 homolog, mitochondrial

358 amino acids

Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway.

Belongs to the GcvT family. CAF17 subfamily.

38.399 kDa

MAAVALLRGAAVGRRSPAWHWRLSGTASHCLARGFGLLGSNPADGVAWTCFRLDGRALVRVRGPDAAPFLLGLSTNELPLSGPPTGAAQPSARAAYAHFLNVQGRTLYDVILYGLPECTEGAPSFLLECDSSVLGALQKHLSMYKIRRKVTVEPSPELHVWAVLPCVPQTSETAPLEERVEGTTMLIRDPRTARMGWRLLTQDDGPALVPRGQLGDLQDYHKYRYQQGIPEGVCDLPPGMALPLESNLVFMNGVSFTKGCYIGQELTARTHHTGVIRKRLFPVKLEGPLPASGVSPGAIVTVTATGQAAGKFRAGQGHVGLALLRSETIKGPLHIKTSESQLVAVTAVVPDWWPTAAK

IBA57

Putative transferase CAF17, mitochondrial

356 amino acids

Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway.

Belongs to the GcvT family. CAF17 subfamily.

38.155 kDa

MATAALLRGATPGRGGPVWRWRLRAAPRCRLAHSSCSPGGDPTAGAAWACFRLDGRTLLRVRGPDAAPFLLGLLTNELPLPSPAAAGAPPAARAGYAHFLNVQGRTLYDVILYGLQEHSEVSGFLLECDSSVQGALQKHLALYRIRRKVTVEPHPELRVWAVLPSSPEACGAASLQERAGAAAILIRDPRTARMGWRLLTQDEGPALVPGGRLGDLWDYHQHRYLQGVPEGVRDLPPGVALPLESNLAFMNGVSFTKGCYIGQELTARTHHMGVIRKRLFPVRFLDPLPTSGITPGATVLTASGQTVGKFRAGQGNVGLALLWSEKIKGPLHIRASEGAQVALAASVPDWWPTVSK

iba57

Putative transferase CAF17 homolog, mitochondrial

354 amino acids

Required for normal heme biosynthesis.

Belongs to the GcvT family.

39.046 kDa

MQRMILFGGALREIVVRSGGLQAHYFLCTSRTRIKTHSQTRAASSTAHFSCYRLPHRTVLNVSGQDTSSFLQGIITNDMNLLGEDSLNAMYAHVLNVQGRTLYDIILYSLKGNPDGLNGVLLECDSTVQDSVMQLLKVYKIRRKVNLSVCPSLSLWALLPHSKEAVLGRPDVTTTDKVLVLEKDPRTELMGWRMITSAQDNPLDIVSACRLGNTEEYHRHRYEIGLPEGVGDLPPGEALPLEANLVYMQGISFSKGCYIGQELTARTHHTGVIRKRLMPVSLSAPAEKLNQGSALQTEGGKPAGKYRTGVDKLGLSLVRLAHAKETLQLKSSGDETVTVLASVPDWWPKTPQEK