Protein
Putative GPI-anchor transamidase
Organism
Caenorhabditis elegans
Function
Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein (By similarity).
Similarity
Belongs to the peptidase C13 family.
Sequence
MRHVLLIFCAIIATEALLNTGLQLKIDELFDTPGHTNNWAVLVCTSKFWFNYRHVSNVLALYHSIKRLGIPDSNIIMMLAEDVPCNSRNPRPGTVYAARAGTNLYGSDVEVDYRGEEVTVESFIRVLTGRHHPATPRSKRLLTDHQSNVLIYLTGHGGDSFMKFQDSEELTNVDLAYAIQTMFEDNRYHEMLVIADSCRSASMYEWIDSPNVLSLSSSLTHEESYSYDVDTDIGVYVIDRYTHYTVNFLTKEVKALNSSANMQDYIDSCPARKCLSNTGVRKDHYPKDVKRVRVTDFFGSSRIFQHLSEEIVLDDEFWA