hop

Gene

hop

Protein

Tyrosine-protein kinase hopscotch

Organism

Drosophila melanogaster

Length

1177 amino acids

Function

Tyrosine kinase of the non-receptor type, phosphorylates the marelle protein. Required maternally for the establishment of the normal array of embryonic segments: involved in the control of pair-rule gene transcription in a stripe-specific manner. Together with Hsp83 and piwi, mediates canalization, also known as developmental robustness, likely via epigenetic silencing of existing genetic variants and suppression of transposon-induced new genetic variation.

Similarity

Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

Mass

135.062 kDa

Sequence

MALANGGEDRMDDSSSGRTSLADSASLTNSSLRSGTSSQSIHTNDGTIRVFNFTTGEFERFHPNMLCEEICNTMCRQLGIAPIAQLLYGIREHSTSRRPSPLVRLDLTWCLPGERLNCQLVYCFRMRFRVPELDSQLELIDGRSHKFLYRQMRYDMRTEQIPEIRYPEHKDKSTGLAVMDMLIDDQEQSEDQQAMRSIEKLYKLYLPPSLWRAHSFFVGSKIREVFRSLKANSLSVERLKWHYVHQVSHLAPTYMTEQFTCTVQYLPNEEVARGSGPIGTSLAHSTSTLASSGSTNTLSTLTTNTNSVALGGSGKKAKRRSTSGGIDVYVRVFPHDSLEPGLKVARVTSEATLKWILVGAVEGIFMISKINDTSVRLEIVGLPKGYEMQFQTEKEMKSFISYLGIYIRLSSKWMQDLCHSYRTPSLEELSSLHCHGPIGGAYSLMKLHENGDKCGSYIVRECDREYNIYYIDINTKIMAKKTDQERCKTETFRIVRKDSQWKLSYNNGEHVLNSLHEVAHIIQADSPDRYRIPASKYDKPPLLLLLLPKNLKAKKTDLQLSEAELQRRNPQIFNPRTDLQWYPDSISLSDDGMMFTMRGDWIQQSPVKDVSVTMKMLKSDGNFMEFFRLAQTWSLIQSPQFLKLYGLTLADPYTMVMEYSRYGPLNKFLHSMPNVTLHCLLDLMHGLVRGMHYLEDNKIIHNYIRCSNLYVTKYDPNSYVLDAKISDPGYPRPYRESDSPWIPVKYYRNLQAAKTDQFAQLWAFATTIYEIFSRCKEDLSTLRQEQLLRQKNLDGNILKMLDQDICPAPIFETIMDGWSDDETKRFSHHDIFSRLNTIKAEILPNYMPPPEIATNGTGDETVIDRSDIPFLPFPRSNMLMVIPLTSECRVIYNMENMIGRGHYGTVYKGHLEFNDKDQPREQVAIKMLNTMQVSTDFHREIGIMRTLSHPNIVKFKYWAEKSHCIIMEYLQSGSFDIYLRFTAPNLNNPRLVSFALDIANGMKYLSDMGLIHRDLAARNILVDHNGDGDCVKISDFGLAQFANSDGYYYAKSKRDIPIRWYSPEAISTCRFSSYSDVWSYGVTLFEMFSRGEEPNLVPIQTSQEDFLNRLQSGERLNRPASCPDFIYDLMQLCWHATPRSRPSFATIVDIITREVATKVTHPTDGHQSPPNQPTDAE

Protein

Tyrosine-protein kinase hopscotch: hop

Gene

HOP

Protein

Hsp70-Hsp90 organizing protein

Organism

Triticum aestivum

Length

581 amino acids

Function

Mediates the association of the molecular chaperones HSP70 and HSP90 (By similarity). Mediates nuclear encoded chloroplast preproteins binding to HSP90 prior to chloroplastic sorting.

Mass

65.097 kDa

Sequence

MADEAKAKGNAAFSAGRFEEAAGHFSDAIALAPANHVLYSNRSAALASIHRYSDALADAEKTVELKPDWAKGYSRLGAAHLGLGDAASAAAAYEKGLALDPSNEGLKAGLADAKKAAAAPPRRAPSGGADAIGQMFQGPELWTKIASDPATRAYLDQPDFMQMLREVQRNPSSLNTYLSDPRMMQVLSLMLNIKIQTPQDSDFSQSSSPSQPPPQQQKQQPETKAREMEPEPQPEPMEVSDEEKERKERKAAALKEKEAGNASYKKKDFETAIQHYTKALELDDEDISYLTNRAAVYIEMGKYDECIEDCDKAVERGRELRADFKMVARALTRKGTALAKLAKNSKDYDIAIETFQKALTEHRNPDTLKRLNEAEKAKKDLEQQEYYDPKLADEEREKGNEMFKQQKYPEAIKHYNEAIRRNPKDARVYSNRAACYTKLGAMPEGLKDAEKCIELDPTFTKGYTRKGAVQFFMKEYEKAMETYQAGLKYDPNNQELLDGIRRCVEQINKANRGDISQEDLQEKQSKAMQDPEIQNILTDPIMRQVLMDFQENPRAAQDHLKDPGVAQKIQKLINAGIVQTR

Protein

Hsp70-Hsp90 organizing protein: HOP

Gene

hop

Protein

Halorhodopsin

Organism

Haloterrigena sp. (strain arg-4)

Length

297 amino acids

Function

Light-driven chloride pump.

Similarity

Belongs to the archaeal/bacterial/fungal opsin family.

Mass

32.042 kDa

Sequence

MRSRTYHDQSVCGPYGSQRTDCDRDTDAGSDTDVHGAQVATQIRTDTLLHSSLWVNIALAGLSILVFLYMARTVRANRARLIVGATLMIPLVSLSSYLGLVTGLTAGPIEMPAAHALAGEDVLSQWGRYLTWTLSTPMILLALGWLAEVDTADLFVVIAADIGMCLTGLAAALTTSSYAFRWAFYLVSTAFFVVVLYALLAKWPTNAEAAGTGDIFGTLRWLTVILWLGYPILWALGVEGFALVDSVGLTSWGYSLLDIGAKYLFAALLLRWVANNERTIAVGQRSGRGAIGDPVED

Protein

Halorhodopsin: hop

Gene

hop

Protein

Halorhodopsin

Organism

Natronomonas pharaonis

Length

291 amino acids

Function

Light-driven anion pump. Binding affinity for the anions is in the order, bromide > chloride > nitrate > azide > bromate and binding is pH dependent.

Similarity

Belongs to the archaeal/bacterial/fungal opsin family.

Mass

31.08 kDa

Sequence

MTETLPPVTESAVALQAEVTQRELFEFVLNDPLLASSLYINIALAGLSILLFVFMTRGLDDPRAKLIAVSTILVPVVSIASYTGLASGLTISVLEMPAGHFAEGSSVMLGGEEVDGVVTMWGRYLTWALSTPMILLALGLLAGSNATKLFTAITFDIAMCVTGLAAALTTSSHLMRWFWYAISCACFLVVLYILLVEWAQDAKAAGTADMFNTLKLLTVVMWLGYPIVWALGVEGIAVLPVGVTSWGYSFLDIVAKYIFAFLLLNYLTSNESVVSGSILDVPSASGTPADD

Protein

Halorhodopsin: hop

Gene

hop

Protein

Halorhodopsin

Organism

Halobacterium sp. (strain SG1)

Length

284 amino acids

Function

Light-driven chloride pump.

Similarity

Belongs to the archaeal/bacterial/fungal opsin family.

Mass

30.256 kDa

Sequence

MIETAAADILAGGMVPLEMTQTQIFEAVQSDTLLASSLWINIALAGLSILLFVYMGRNVEDPRAQLIFVATLMVPLVSISSYTGLVSGLTVSFLEMPAGHALAGQEVLTPWGRYLTWALSTPMILIAVGLLAGSNTTKLFTAVVADIGMCVTGLAAALTTSSYLLRWVWYAISCAFFVVVLYILLAEWAEDAEIAGTADIFNTLKVLTVVLWLGYPIFWALGAEGLAVLDVAITSWAYSGMDIVAKYLFAFLLLRWVVNNERTVADVASGLGSGSRGGAAPADD

Protein

Halorhodopsin: hop

Gene

hop

Protein

Halorhodopsin

Organism

Halorubrum sodomense

Length

282 amino acids

Function

Light-driven chloride pump.

Similarity

Belongs to the archaeal/bacterial/fungal opsin family.

Mass

30.143 kDa

Sequence

MMETAADALASGTVPLEMTQTQIFEAIQGDTLLASSLWINIALAGLSILLFVYMGRNLEDPRAQLIFVATLMVPLVSISSYTGLVSGLTVSFLEMPAGHALAGQEVLTPWGRYLTWALSTPMILVALGLLAGSNATKLFTAVTADIGMCVTGLAAALTTSSYLLRWVWYVISCAFFVVVLYVLLAEWAEDAEVAGTAEIFNTLKLLTVVLWLGYPIFWALGAEGLAVLDVAVTSWAYSGMDIVAKYLFAFLLLRWVVDNERTVAGMAAGLGAPLARCAPADD

Protein

Halorhodopsin: hop

Gene

hop

Protein

Halorhodopsin

Organism

Halobacterium halobium (strain port)

Length

276 amino acids

Function

Light-driven chloride pump.

Similarity

Belongs to the archaeal/bacterial/fungal opsin family.

Mass

29.045 kDa

Sequence

MTAASTTATTMLQATQSDVLQEIQSNFLLNSSIWVNIALAGVVILLFVAMGRDIESPRAKLIWVATMLVPLVSISSYAGLASGLTVGFLQMPPGHALAGQEVLSPWGRYLTWTFSTPMILLALGLLADTDIASLFTAITMDIGMCVTGLAAALITSSHLLRWVFYGISCAFFVAVLYVLLVQWPADAEAAGTSEIFGTLKILTVVLWLGYPILWALGSEGVALLSVGVTSWGYSGLDILAKYVFAFLLLRWVAANEGAVSGSGMSIGSGGAAPADD

Protein

Halorhodopsin: hop

Gene

hop

Protein

Halorhodopsin

Organism

Halobacterium halobium (strain shark)

Length

276 amino acids

Function

Light-driven anion pump.

Similarity

Belongs to the archaeal/bacterial/fungal opsin family.

Mass

29.041 kDa

Sequence

MTAVSTTATTVLQATQSDVLQEIQSNFLLNSSIWVNIALAGVVILLFVAMGRDLESPRAKLIWVATMLVPLVSISSYAGLASGLTVGFLQMPPGHALAGQEVLSPWGRYLTWTFSTPMILLALGLLADTDIASLFTAITMDIGMCVTGLAAALITSSHLLRWVFYGISCAFFVAVLYVLLVQWPADAEAAGTSEIFGTLKILTVVLWLGYPILWALGSEGVALLSVGVTSWGYSGLDILAKYVFAFLLLRWVAANEGTVSGSGMGIGSGGAAPADD

Protein

Halorhodopsin: hop

Gene

hop

Protein

Halorhodopsin

Organism

Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Length

276 amino acids

Function

Light-driven chloride pump.

Similarity

Belongs to the archaeal/bacterial/fungal opsin family.

Mass

29.043 kDa

Sequence

MTAASTTATTVLQATQSDVLQEIQSNFLLNSSIWVNIALAGVVILLFVAMGRDLESPRAKLIWVATMLVPLVSISSYAGLASGLTVGFLQMPPGHALAGQEVLSPWGRYLTWTFSTPMILLALGLLADTDIASLFTAITMDIGMCVTGLAAALITSSHLLRWVFYGISCAFFVAVLYVLLVQWPADAEAAGTSEIFGTLKILTVVLWLGYPILWALGSEGVALLSVGVTSWGYSGLDILAKYVFAFLLLRWVAANEGTVSGSGMGIGSGGATPADD

Protein

Halorhodopsin: hop

Gene

hop

Protein

Halorhodopsin

Organism

Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)

Length

274 amino acids

Function

Light-driven chloride pump.

Similarity

Belongs to the archaeal/bacterial/fungal opsin family.

Mass

28.874 kDa

Sequence

MSITSVPGVVDAGVLGAQSAAAVRENALLSSSLWVNVALAGIAILVFVYMGRTIRPGRPRLIWGATLMIPLVSISSYLGLLSGLTVGMIEMPAGHALAGEMVRSQWGRYLTWALSTPMILLALGLLADVDLGSLFTVIAADIGMCVTGLAAAMTTSALLFRWAFYAISCAFFVVVLSALVTDWAASASSAGTAEIFDTLRVLTVVLWLGYPIVWAVGVEGLALVQSVGVTSWAYSVLDVFAKYVFAFILLRWVANNERTVAVAGQTLGTMSSDD

Protein

Halorhodopsin: hop

Gene

hop

Protein

Halorhodopsin

Organism

Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)

Length

274 amino acids

Function

Light-driven chloride pump.

Similarity

Belongs to the archaeal/bacterial/fungal opsin family.

Mass

28.874 kDa

Sequence

Protein

Halorhodopsin: hop

Gene

hop

Protein

Halorhodopsin

Organism

Halobacterium halobium (strain mex)

Length

206 amino acids

Function

Light-driven chloride pump.

Similarity

Belongs to the archaeal/bacterial/fungal opsin family.

Mass

21.871 kDa

Fragment

single

Sequence

IALAGLSILLFVYMGRNVEDPRAQLIFVATLMVPLVSISSYTGLVSGLTVGFLEMPAGHALAGMGAGPEGGVFTPWGRYLTWAFSTPMILIALGLLAGSNMSKLFTAVVADVGMCITGLAAALTTSSYLLRWVWYGISCAFFVVVLYILLAEWAKDAEVAGTADIFNTLKVLTVVLWLGYPIFWALGAEGLAVLDIAITSWAYSGM

Protein

Halorhodopsin: hop