hnf1a-a

Gene

hnf1a-a

Protein

Hepatocyte nuclear factor 1-alpha-A

Organism

Xenopus laevis

Length

605 amino acids

Function

Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreas and liver (By similarity). Binds to the hepatocyte specific promoter element HP1. Binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.

Similarity

Belongs to the HNF1 homeobox family.

Mass

66.577 kDa

Sequence

MASQLSYLQRELLQALLESGVTKEALKKALADGDDYTYPNVPLDDIRNLDEGENCVQLPNGLGESHISEDESSDDGEDFTPPIMKELERLSPEEAAHQKAVVERLLQEDSWHVAKLVKSYLQQHNIPQREVVETTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVGKQREIARLFTFTEFTHAGQGLITDDMSCDEVPTKKMRRNRFKWGPASQQILFQAYERQKNPSKEEREALVEECNRAECLQRGVSPSQAQGLGSNLVTEVRVYNWFANRRKEEAFRHKLAMDTYNGQQNSAPTLSAHDLPHGKTYGFRYIQDSSTDRSAVMANSQSTPSPSALEPSHSLMNSDSKMIPVSGGSLPPVSTLTALHNVDHSQHTLGQTQNLIMASLPSVMTIGTDTALGPAFSNPGSSTLVIGLASQTQSVPVINSVGSSLTTLQSVQFSQQLHPSHQLHPSHQQPIVQQVQSHMAQNPFMATMAQLQSPHAIYSHKPDVAQYASAGFFPQTMVITDTSNLGTLTSLTPSKQVVPLHTTAHGDAPGSQLQNQDSSILHLPLCHRLSPIPTVSSASLVHYHNSSSPENHSHLLSPSHNTIDSFISTQMASSSQ

Protein

Hepatocyte nuclear factor 1-alpha-A: hnf1a-a