hlh-26

Gene

hlh-26

Protein

Helix-loop-helix protein 26

Organism

Caenorhabditis elegans

Length

210 amino acids

Function

Binds DNA via the E-box sequence 5'-CACGTG-3'. Binds DNA as a homodimer. Represses lag-2 transcription during embryogenesis via Notch signaling, in an unc-37-dependent manner. Also represses tbx-37 independent of Notch signaling.

Mass

23.874 kDa

Sequence

MSSSPTSSSSGSPSSHGHRSETEKQRRDDTNDLLNEFKKIVQKSESEKLSKEEVLFRIVKLLSGIQLHHESFSTSPGPIRSIKKIKSDREQVRRNKRVAAYRELRKFIALNNLSSSEEIDKMENLKVLEIIFEVIRGKSITCTVPCLPFPILPFLPVFPVYSPLVFNSYNQFSLYPPHMPTVQIPIVPSSSFEIDALEIEENEKDIDIVG

Protein

Helix-loop-helix protein 26: hlh-26