Protein
Modification methylase HindV
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Function
This methylase recognizes the double-stranded sequence GRCGYC, causes specific methylation on C-? on both strands, and protects the DNA from cleavage by the HindV endonuclease.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Sequence
MKCVDLFSGCGGLSLGFELAGFEICAAFENWEKAIEIYKNNFSHPIYNIDLRNEKEAVEKIKKYSPDLIMGGPPCQDFSSAGKRDISLGRADLTYSFANIVCNIRPKWFVMENVEQIKKSHILQDIINQFIDFGYGLTSAILDASYCGVPQSRTRFSLIGKLNSEHNFLIPTLSRKLSDKPMTVRDYLGNSLNLEFYYRHPRNYNRRGIFSIDEPSPTIRGVNRPIPKGYNINSCDPKGVELAKVRPLTTIERSYIQTFPKSFLFSGTKTDLEQMIGNAVPVNLAKFVASAIINFEKEPIRSMG