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hilA

Gene
hilA
Protein
Transcriptional regulator HilA
Organism
Salmonella paratyphi A (strain ATCC 9150 / SARB42)
Length
553 amino acids
Function
The main transcriptional regulator of the Salmonella pathogenicity island 1 (SPI1) gene expression. Activates the expression of invasion genes by a direct action at their promoters and also indirectly by increasing the level of invF. Also binds upstream of prgH and directly activates the expression of prgHIJK operon (By similarity).
Mass
63.071 kDa
Sequence
MPHFNPVPVSNKKFVFDDFILNMDGSLLRSEKKVNIPPKEYAVLVILLEAAGEIVSKNTLLDQVWGDAEVNEESLTRCIYALRRILSEDKEHRYIETLYGQGYRFNRPVVVVSPPAPQPTTHTLAILPFQMQDQVQSESLHYSIVKGLSQYAPFGLSVLPVTITKNCRSVKDILELMDQLRPDYYISGQMIPDGNDNIVQIEIVRVKGYHLLHQESIKLIEHQPASLLQNKIANLLLRCIPGLRWDTKQISELNSIDSTMVYLRGKHELNQYTPYSLQQALKLLTQCVNMSPNSIAPYCALAECYLSMTQMGIFDKQNAMIKAKEHAIKATELDHNNPQALGLLGLINTIHSEYIVGSLLFKQANLLSPISADIKYYYGWNLFMAGQLEEALQTINECLKLDPTRAAAGITKLWITYYHTGIDDAIRLGDELRSQHLQDNPILLSMQVMFLSLKGKHELARKLTKEISTQEITGLIAVNLLYAEYCQNSERALPTIREFLESEQRIDNNPGLLPLVLVAHGEAIAEKMWNKFKNEDNIWFKRWKQDPRLIKLR

Gene
hilA
Protein
Transcriptional regulator HilA
Organism
Salmonella typhi
Length
553 amino acids
Function
The main transcriptional regulator of the Salmonella pathogenicity island 1 (SPI1) gene expression. Activates the expression of invasion genes by a direct action at their promoters and also indirectly by increasing the level of invF. Also binds upstream of prgH and directly activates the expression of prgHIJK operon (By similarity).
Mass
63.04 kDa
Sequence
MPHFNPVPVSNKKFVFDDFILNMDGSLLRSEKKVNIPPKEYAVLVILLEAAGKIVSKNTLLDQVWGDAEVNEESLTRCIYALRRILSEDKEHRYIETLYGQGYRFNRPVVVVSPPAPQPTTHTLAILPFQMQDQVQSESLHYSIVKGLSQYAPFGLSVLPVTITKNCRSVKDILELMDQLRPDYYISGQMIPDGNDNIVQIEIVRVKGYHLLHQESIKLIEHQPASLLQNKIANLLLRCIPGLRWDTKQISELNSIDSTMVYLRGKHELNQYTPYSLQQALKLLTQCVNMSPNSIAPYCALAECYLSMAQMGIFDKQNAMIKAKEHAIKATELDHNNPQALGLLGLINTIHSEYIVGSLLFKQANLLSPISADIKYYYGWNLFMAGQLEEALQTINECLKLDPTRAAAGITKLWITYYHTGIDDAIRLGDELRSQHLQDNPILLSMQVMFLSLKGKHELARKLTKEISTQEITGLIAVNLLYAEYCQNSERALPTIREFLESEQRIDNNPGLLPLVLVAHGEAIAEKMWNKFKNEDNIWFKRWKQDPRLIKLR

Gene
hilA
Protein
Transcriptional regulator HilA
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Length
553 amino acids
Function
The main transcriptional regulator of the Salmonella pathogenicity island 1 (SPI1) gene expression. Activates the expression of invasion genes by a direct action at their promoters and also indirectly by increasing the level of InvF. Also binds upstream of prgH and directly activates the expression of prgHIJK operon.
Mass
63.041 kDa
Sequence
MPHFNPVPVSNKKFVFDDFILNMDGSLLRSEKKVNIPPKEYAVLVILLEAAGEIVSKNTLLDQVWGDAEVNEESLTRCIYALRRILSEDKEHRYIETLYGQGYRFNRPVVVVSPPAPQPTTHTLAILPFQMQDQVQSESLHYSIVKGLSQYAPFGLSVLPVTITKNCRSVKDILELMDQLRPDYYISGQMIPDGNDNIVQIEIVRVKGYHLLHQESIKLIEHQPASLLQNKIANLLLRCIPGLRWDTKQISELNSIDSTMVYLRGKHELNQYTPYSLQQALKLLTQCVNMSPNSIAPYCALAECYLSMAQMGIFDKQNAMIKAKEHAIKATELDHNNPQALGLLGLINTIHSEYIVGSLLFKQANLLSPISADIKYYYGWNLFMAGQLEEALQTINECLKLDPTRAAAGITKLWITYYHTGIDDAIRLGDELRSQHLQDNPILLSMQVMFLSLKGKHELARKLTKEISTQEITGLIAVNLLYAEYCQNSERALPTIREFLESEQRIDNNPGLLPLVLVAHGEAIAEKMWNKFKNEDNIWFKRWKQDPRLIKLR