Protein
Modification methylase HhaII
Organism
Haemophilus parahaemolyticus
Function
This methylase recognizes the double-stranded sequence GANTC, causes specific methylation on A-2 on both strands, and protects the DNA from cleavage by the HhaII endonuclease.
Similarity
Belongs to the N(4)/N(6)-methyltransferase family.
Sequence
MFSHQDYLSFVNKKNKMNGIDLFKLIPDKAVKIAFFDPQYRGVLDKMSYGNEGKGRGKERAALPQMTDEIIQQFINEFERVLLPNGYLFLWVDKFHLVEGVKPWLENTPSLSVVDMLTWDKQKIGMGYRTRRRSEYLVVIQKEPKKAKITWTLHNIPDVWAEKLQSKPHTHSKPIEMQKQLILATTQEGDLILDPASGGYSVFECCKQTNRNFIGCDLIFGDDENEQD