Protein
4'-phosphopantetheinyl transferase HetI
Organism
Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Function
Probably activates the acyl carrier protein (ACP) domain of HetM, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. May be required for maintaining vegetative growth and probably acts via HetN to inhibit differentiation.
Similarity
Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
Sequence
MLQHTWLPKPPNLTLLSDEVHLWRIPLDQPESQLQDLAATLSSDELARANRFYFPEHRRRFTAGRGILRSILGGYLGVEPGQVKFDYESRGKPILGDRFAESGLLFNLSHSQNLALCAVNYTRQIGIDLEYLRPTSDLESLAKRFFLPREYELLRSLPDEQKQKIFFRYWTCKEAYLKATGDGIAKLEEIEIALTPTEPAKLQTAPAWSLLELVPDDNCVAAVAVAGFGWQPKFWHY