hemC2

Gene

hemC2

Protein

Porphobilinogen deaminase 2

Organism

Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)

Length

314 amino acids

Function

Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

Similarity

Belongs to the HMBS family.

Mass

33.545 kDa

Sequence

MSGMSALELIRIVSRDSPMALAQVARVRAELAALHPRTRTEVVAVKTTGDKWMGDLSKVDGKGAFTKEVDAALLAGEADLAVHCVKDVPADRPLPAGTMFAAFLKRDDIRDALVHPGGLTLDELPPGTRIGTSSVRRVAQLAAAYPHLECVPFRGNANRRLEKLAAGEADALLLAVSGLERIGREDVITEVLEPETMMPPIGAGILALQCREGDTGLIETISELGDPGTHREATAERMFLHVLQGHCNSPIAGYARTERNGELSLRASVFTLDGKTVLNAHEWAGRLDPATLGTSVAVALLRQGARELIDDIPH

Protein

Porphobilinogen deaminase 2: hemC2

Gene

hemC2

Protein

Porphobilinogen deaminase 2

Organism

Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)

Length

313 amino acids

Function

Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

Similarity

Belongs to the HMBS family.

Mass

33.413 kDa

Sequence

MRMSAPELIRIVSRDSPMALAQVERVRAELAALHPGVRTEVVPVRTTGDKWLGDLSQVEGKGAFTKEVDAALLSGEADLAVHCVKDVPADRPLPAGTVFAAFLKRDDVRDALVHPDGLTLDELPDGTRVGTSSVRRVAQLAATHPHLRCVPFRGNANRRLAKLAAGEADALLLAVSGLERIGRTDVISEVLSTETMMPPIGAGILALQCREGDRALIEAVSALGDPRTHREATAERMFLHVLQGHCNSPIAGHAQVDRSGELSLRACVFTPDGKVRLNAHEWAGRLDPATLGTSVAVALLRQGAREIIDGIAH

Protein

Porphobilinogen deaminase 2: hemC2