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hdrB2

Gene
hdrB2
Protein
Ferredoxin/F(420)H(2)-dependent CoB-CoM heterodisulfide reductase subunit B
Organism
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Length
300 amino acids
Function
Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). Catalyzes the transfer of electrons from ferredoxin to CoM-S-S-CoB during methanogenesis from acetate. Electrons transfer from ferredoxin to CoM-S-S-CoB via HdrA2, HdrC2 and HdrB2. In addition, the complex can use electron bifurcation to direct electron pairs from reduced coenzyme F420 towards the reduction of both ferredoxin and CoB-CoM heterodisulfide. This activity may take place during Fe(III)-dependent anaerobic methane oxidation.
Similarity
Belongs to the HdrB family.
Mass
32.819 kDa
Sequence
MAKLSLFRGCIVPNRYPGIEKATKLCLQKLEVDAVDLPGASCCPAPGVFKSFDKATWLALASRNIVLSERMGRDILTVCNGCYGSLADANIELKNDPEMKACTNSCLKEIGMEYKGTAEVRHIIEFLYKELGPEKLKSFITTPLDLKVALHYGCHLIKPSKERNLGETEAPVFFDELVEATGAKSVDYTDKMMCCGAGGGVRSGHAAESLEMLEHKLACIRNAGVDCIVNACPFCHLQFDRGQLAVNEKFGTDYSIPVLHYSQLLGLALGFSPDELGIEQNAIQNIEFLAKIYEISAGLR

Gene
hdrB2
Protein
CoB--CoM heterodisulfide reductase subunit B 2
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Length
295 amino acids
Function
Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
Similarity
Belongs to the HdrB family.
Mass
32.789 kDa
Sequence
MKYAFFLGCIMPHRYPGVEKATKIVMEELGVELEYMPGASCCPAPGVFGSFDQKTWLTLAARNLCIAEEMGLDIVTVCNGCYGSLFEAAHILHENKEALDFVNEKLDKIGKQYKGTIKVRHFAELIYKDIGVDKIKEKVVKPLDVLNVAIHYGCHFLKPSDVKHLDSPERPKLLEEIVAATGAKPVMYRDYLMCCGAGGGVRARFLPTALDMTKEKIRNMLEAGADCTVNVCPFCHLQFDRGQVEIKEKFGEEYKLPVLHLSQLLGLAFGMKPEDLAVSVHAIPVDPVLKKLGIE

Gene
hdrB2
Protein
H(2)/formate:CoB-CoM heterodisulfide,ferredoxin reductase subunit B2
Organism
Methanococcus maripaludis (strain S2 / LL)
Length
293 amino acids
Function
Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
Similarity
Belongs to the HdrB family.
Mass
32.026 kDa
Sequence
MKYAFFLGCIMPNRYAGVESATRTVMEKLGVELVDMPGASCCPAPGVFGSFDQKTWLTLAARNLVIAEEMGTDIVTVCNGCYGSLYEAAHMLHENKEALAMVNEQLKEIGKEYKGTVHVRHFAELIYKEIGVDKIRENVVKPLAVNIGVHYGCHFLKPTAAKGLGNAEHPTMLDELVEATGAKSVDYKDKMMCCGAGGGVRAKELDLALSMTQEKIENMLAVGADATVNVCPFCQLQFDRGQVEIKEKLGNEYNFPVVHLSQLLGLAMGMDPKEVALDVNFISPEPLLQKLGY