Protein
Transcriptional activator hacA
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Function
Transcriptional activator involved in the unfolded protein response (UPR) pathway. Recognizes and binds to the UPR element (UPRE) in the promoter of UPR-regulated genes. Increases the synthesis of endoplasmic reticulum-resident proteins required for protein folding as well as components of the secretory pathway (By similarity).
Similarity
Belongs to the bZIP family.
Sequence
MKSADRFSPVKMEDAFANSLPTTPSLEVPVLTVSPADTSLQTKNVVAQTKPEEKKPAKKRKSWGQELPVPKTNLPPRKRAKTEDEKEQRRIERVLRNRAAAQTSRERKRLEMEKLESEKIDMEQQNQFLLQRLAQMEAENNRLSQQVAQLSAEVRGSRHSTPTSSSPASVSPTLTPTLFKQEGDEVPLDRIPFPTPSVTDYSPTLKPSSLAESPDLTQHPAVSVGGLEGDESALTLFDLGASIKHEPTHDLTAPLSDDDFRRLFNGDSSLESDSSLLEDGFAFDVLDSGDLSAFPFDSMVDFDTEPVTLEDLEQTNGLSDSASCKAASLQPSHGASTSRCDGQGIAAGSA