Protein
Sorbitol dehydrogenase
Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Function
Polyol dehydrogenase that catalyzes the NAD(+)-dependent oxidation of various sugar alcohols. Is active with D-sorbitol (D-glucitol), xylitol and L-iditol as substrates, leading to the C2-oxidized products D-fructose, D-xylulose and L-sorbose, respectively.
Similarity
Belongs to the zinc-containing alcohol dehydrogenase family.
Sequence
MKALVKTQHGTGHFAVQEKPEPTPGKHQVKIKVKYTGVCGSDIHTYEGHYPVAAPVTLGHEFSGEIVELGEGVTGFNVGDRVTSETTYSICGKCSYCTSGDYNLCSHRKGLGNQQDGSFAKYVIARQESLHHLPAGVDDRSAAMTEPLACTHHAIAKTSINKGDLVVVTGPGPIGLLAAQVAKSHGGTVIITGLSNDQVRLKKAKEVGIDYAIDTQEVDIKELVSELTDGYGADVVLECSGAVPAAKQGIDLLRKKGQYAQVGLFAQPEIQFNFEKIIQKEISVVGSRSQKPADWEPALSLLNEKKVNAKTLVTHEYTISEWDKAYHAIKSGEAIKVLLTPID