guaD

Gene

guaD

Protein

Guanine deaminase

Organism

Dictyostelium discoideum

Length

450 amino acids

Function

Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

Similarity

Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.

Mass

50.73 kDa

Sequence

MMKANKIIKLFKGTVIHSIEIGKVEILPNSLIGIDEDGVIQHMKSNYEDLKQLEKDVTMICTDNGINEQESVIDMGNKFLIPGFIDTHAHAPQYHNAGTGTDLPLLKWLEKYTFPVESKFKDLIFAENVYGKVVDRMLRHGTTTCCYYATIHLEASELLAEIVSKRGQRAFIGKVCMDRHSPDHYVETTEQSISNTKEFVDRILAKGNPLVQPIVTPRFAPSCTDELMVALGNLSHEKQTLIQSHLSENKDEIEWVKSLYPGIESYTHVYKHFNLLNERTIMAHCVHLSDEEIKLISTQQTAISHCPISNFTLSSGNLDVRKVLEANIKLGLGSDISGGYHPSILQVIRDSIKCSNSHFFNNGNHTPLTFEEAFYLATVGGSKVVNLDHRIGNFIVGKDFDAQIIDPFVQNSPFDCFDGETLKDIFQKFIYLGDDRNLSSLYIKGNKIKF

Protein

Guanine deaminase: guaD

Gene

guaD

Protein

Probable guanine deaminase

Organism

Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

Length

439 amino acids

Function

Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

Similarity

Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.

Mass

46.688 kDa

Sequence

MKIYRSTLLHTPASPFAVPDALQTFSDGALAVGDTGTIAHLGTFTEVLAEVRAACPDAEVHDLRGGVLLPGFIDTHVHYPQVRVLGGLGMALLEWLDRNTLPEEARLADAAYARTIAGEFLHGLASHGTTTALVFGSHFAGAMDEFFAEAAARGLRVVAGQVVSDRLLRPELHTTPERAYAEGKALIERWHGQGRSLYAVTPRFSLSASEGILDACAALLTEFPDVRFTSHINENNQEIEVVRGLFPGARDYLDTYERAGLVTPRSVFAHNVHPNERELGVLAAQRCSVAHCPCSNSALGSGLFPLRRHLAAGVHVALGTDVGGGTGFSLLKEGLQAYFMQQLLGEEGAALSPAHLLYLATLAGAQALGLDGQVGDFTPGKQFDAVWLRPRAGSTLATVLAHAESEERTLAALFALGTGDDVERVWVGGGVVFAREAEA

Protein

Probable guanine deaminase: guaD

Gene

guaD

Protein

Guanine deaminase

Organism

Escherichia coli (strain K12)

Length

439 amino acids

Function

Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

Similarity

Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.

Mass

50.244 kDa

Sequence

MMSGEHTLKAVRGSFIDVTRTIDNPEEIASALRFIEDGLLLIKQGKVEWFGEWENGKHQIPDTIRVRDYRGKLIVPGFVDTHIHYPQSEMVGAYGEQLLEWLNKHTFPTERRYEDLEYAREMSAFFIKQLLRNGTTTALVFGTVHPQSVDALFEAASHINMRMIAGKVMMDRNAPDYLLDTAESSYHQSKELIERWHKNGRLLYAITPRFAPTSSPEQMAMAQRLKEEYPDTWVHTHLCENKDEIAWVKSLYPDHDGYLDVYHQYGLTGKNCVFAHCVHLEEKEWDRLSETKSSIAFCPTSNLYLGSGLFNLKKAWQKKVKVGMGTDIGAGTTFNMLQTLNEAYKVLQLQGYRLSAYEAFYLATLGGAKSLGLDDLIGNFLPGKEADFVVMEPTATPLQQLRYDNSVSLVDKLFVMMTLGDDRSIYRTYVDGRLVYERN

Protein

Guanine deaminase: guaD

Gene

guaD

Protein

Guanine deaminase

Organism

Bacillus subtilis (strain 168)

Length

156 amino acids

Function

Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

Similarity

Belongs to the cytidine and deoxycytidylate deaminase family.

Mass

17.156 kDa

Sequence

MNHETFLKRAVTLACEGVNAGIGGPFGAVIVKDGAIIAEGQNNVTTSNDPTAHAEVTAIRKACKVLGAYQLDDCILYTSCEPCPMCLGAIYWARPKAVFYAAEHTDAAEAGFDDSFIYKEIDKPAEERTIPFYQVTLTEHLSPFQAWRNFANKKEY

Protein

Guanine deaminase: guaD