Protein
Glutathione S-transferase P 10
Organism
Caenorhabditis elegans
Function
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Responsible for approximately one-third of 4-hydroxy-2-nonenal conjugation (Ref.1, PubMed:16164425, PubMed:16300482). May play a role in the detoxification of reactive oxygen species produced during pathogenic bacterial infection (PubMed:22216003).
Similarity
Belongs to the GST superfamily. Pi family.
Sequence
MAVPQLYYFTIRGFGEYIRLLFLDNGIKFEDIRFDYEGNEWQEFKKGMLLGQLPCLKVDGQEIVQTGAIMRHLGRVHGLNGSNEQEATFLDMFFEGVRDVRMKYVRYIYYDEGTREDCVNKTIPEALVKLEELFKAHSGDFIIGNKISYADYILFEELDVYHVLDANILDKFPTLKSFWERMWKRPNLNAYLEKRKADKVWINAIEKGMN