gsr-1

Glutathione reductase, mitochondrial

473 amino acids

Maintains high levels of reduced glutathione in the cytosol (PubMed:23593298). Involved in resistance to oxidative stress and starvation (PubMed:23593298). Together with thioredoxin reductase txtr-1, required for the reduction of disulfide groups in the cuticle during molting (PubMed:21199936).

Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

51.467 kDa

MLRFRCILSTSRSIMSGVKEFDYLVIGGGSGGIASARRAREFGVSVGLIESGRLGGTCVNVGCVPKKVMYNCSLHAEFIRDHADYGFDVTLNKFDWKVIKKSRDEYIKRLNGLYESGLKGSSVEYIRGRATFAEDGTVEVNGAKYRGKNTLIAVGGKPTIPNIKGAEHGIDSDGFFDLEDLPSRTVVVGAGYIAVEIAGVLANLGSDTHLLIRYDKVLRTFDKMLSDELTADMDEETNPLHLHKNTQVTEVIKGDDGLLTIKTTTGVIEKVQTLIWAIGRDPLTKELNLERVGVKTDKSGHIIVDEYQNTSAPGILSVGDDTGKFLLTPVAIAAGRRLSHRLFNGETDNKLTYENIATVVFSHPLIGTVGLTEAEAVEKYGKDEVTLYKSRFNPMLFAVTKHKEKAAMKLVCVGKDEKVVGVHVFGVGSDEMLQGFAVAVTMGATKKQFDQTVAIHPTSAEELVTMRGGVKPE