Protein
Transcription factor gsfR2
Organism
Penicillium aethiopicum
Function
Transcription factor that regulates expression of the gene cluster that mediates the biosynthesis of Griseofulvin, an important antifungal drug that has been in use for a long time for treating dermatophyte infections (PubMed:20534346).
Sequence
MPPLYRRSCITCVQSKRKCDQGLPKCQRCLAKNIHCEYNPRYPNRRRQTTERNVDENVSLVEPIAEEPSRGCQLQRSPARPTSPTHSPHANDIFFNFANDPFNLESIPQDNFLNSTIFEDVVTQQAPNDTERITSDTTAQARVEFAAKKLSVIPKIFSQQGQTMFIHRQLFQDRAPPALQDALSACALYCLKSTENQTLVFRNLEHKRKQLISSIDPLLASKLDLLEALQALVLYQIISLFDGDIRLRAQAEADEPVLLMWAAQLTLRTPQFQPPLGLSNPQSLAGSASMDWGRWLIEESSRRTLITASMLKGVYSFVKLGYDTVPDMRMSFTAQAVLWNSQSEISWRRAYKEKERLEIQVTHWDETIAKAKANDLEELGVLIMVMLKGTGATGEWLGHSQNIRYGLEEAYYGSV