gmd

Gene

Gmd

Protein

GDP-mannose 4,6 dehydratase

Organism

Drosophila melanogaster

Length

395 amino acids

Function

Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.

Similarity

Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

Mass

44.784 kDa

Sequence

MLNTRLIAMSTSDGAPETKKQRPESSSNGSKDQNGTEAGAEGDSRDKVALITGITGQDGSYLAEFLLKKDYEVHGIIRRASTFNTTRIEHLYADPKAHKGGRMKLHYGDMTDSSSLVKIINMVKPTEIYNLAAQSHVKVSFDLSEYTAEVDAVGTLRILDAIRTCGMEKNVRFYQASTSELYGKVVETPQNEQTPFYPRSPYACAKMYGFWIVINYREAYNMYACNGILFNHESPRRGENFVTRKITRSVAKIYHKQMEYFELGNLDSKRDWGHASDYVEAMWMMLQRESPSDYVIATGETHSVREFVEAAFKHIDREITWKGKGVDEVGVENGTGIVRVRINPKYFRPTEVDLLQGDASKANRELNWTPKVTFVELVSDMMKADIELMRKNPIA

Protein

GDP-mannose 4,6 dehydratase: Gmd

Gene

gmd

Protein

GDP-mannose 4,6-dehydratase

Organism

Shigella flexneri

Length

373 amino acids

Function

Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.

Similarity

Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

Mass

42.047 kDa

Sequence

MSKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHYGDLSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYTADVDAMGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVAKLYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYLGNMDSLRDWGHAKDYVKMQWMMLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRFEGTGVEEKGIVVSVTGHDAPGVKPGDVIIAVDPRYFRPAEVETLLGDPTKAHEKLGWKPEITLREMVSEMVANDLEAAKKHSLLKSHGYDVAIALES

Protein

GDP-mannose 4,6-dehydratase: gmd

Gene

gmd

Protein

GDP-mannose 4,6-dehydratase

Organism

Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

Length

373 amino acids

Function

Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.

Similarity

Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

Mass

42.053 kDa

Sequence

MNKKVALITGITGQDGSYLAEFLLEKGYEVHGIKRRSSLFNTQRVDHLYKDPHEEDVNFKLHYGDLTDSSNLTRILAEVQPDEVYNLGAQSHVAVSFQSPEYTADVDAIGTLRLLEAIRFLGLTKKTKFYQASTSELYGLVQEIPQKETTPFYPRSPYAVAKMYAYWITINYRESYGIYACNGILFNHESPRRGETFVTRKITRGMANIAQGLEKCLFMGNLDALRDWGHAKDYVKMQWMMLQQDEPRDFVIATGVQYSVREFIDMSARELGIELEFVGKGVDEKAVVKSVIGTKAPAIKVGDIIVAVDPAYFRPAEVETLLGDPSLAKKELGWVPEITLQQMVSEMVASDLEQAQSHALLKKHGYNVNVSVE

Protein

GDP-mannose 4,6-dehydratase: gmd

Gene

gmd

Protein

GDP-mannose 4,6-dehydratase

Organism

Escherichia coli O157:H7

Length

373 amino acids

Function

Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.

Similarity

Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

Mass

42.047 kDa

Sequence

Protein

GDP-mannose 4,6-dehydratase: gmd

Gene

gmd

Protein

GDP-mannose 4,6-dehydratase

Organism

Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

Length

373 amino acids

Function

Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.

Similarity

Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

Mass

42.047 kDa

Sequence

Protein

GDP-mannose 4,6-dehydratase: gmd

Gene

gmd

Protein

GDP-mannose 4,6-dehydratase

Organism

Escherichia coli (strain K12)

Length

373 amino acids

Function

Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.

Similarity

Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

Mass

42.047 kDa

Sequence

Protein

GDP-mannose 4,6-dehydratase: gmd

Gene

gmd

Protein

GDP-mannose 4,6-dehydratase

Organism

Vibrio cholerae

Length

372 amino acids

Function

Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.

Similarity

Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

Mass

41.992 kDa

Sequence

MKKKALITGVTGQDGSYLAEFLLAKGYEVHGIKRRASSFNTQRVDHIYQDPHVDNASFILHYGDLTDSSNLTRILQEVKPDEVYNLGAQSHVAVSFESPEYTADVDAMGTLRLLEAIRLLGLEKTTKFYQASTSELYGLVQETPQKETTPFYPRSPYAVAKMYAYWIVVNYRESYGMYACNGILFNHESPRRGETFVTRKITRGLANIAQGLEKCLYMGNMDALRDWGHAKDYVRMQWMMLQQDQPEDFVIATGVQYSVRQFIEWSAKELGVTLTFEGQGVDEKGIVTAIEGDKAPALKVGDVVVQIDPRYFRPAEVETLLGDPSKAKQKLGWTPEITVQEMCAEMVMEDLKVAQRHALLKLHGHDVPVSVE

Protein

GDP-mannose 4,6-dehydratase: gmd

Gene

gmd

Protein

GDP-mannose 4,6-dehydratase

Organism

Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)

Length

372 amino acids

Function

Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.

Similarity

Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

Mass

42.122 kDa

Sequence

MKKALITGITGQDGSYLAEFLLEKGYQVHGIKRRSSSFNTSRIDHIYQDPHEVNPHFFLHYGDLTDTSNLIRLVKEIQPDEIYNLGAQSHVAVSFESPEYTADVDAMGTLRLLEAVRINGLEHKTRFYQASTSELYGLVQEIPQRETTPFYPRSPYAVAKMYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANIALGLEDCLYLGNMDSLRDWGHAKDYVRMQWMMLQQDQPEDFVIATGKQITVREFVRMSAKEAGIEIEFSGKGIDEIATISAISDEYATSAKVGDIIVRVDPRYFRPAEVETLLGDPSKAKEKLGWVPEITVEEMCAEMVAGDLQQAKQHALLKANGFDVSITLES

Protein

GDP-mannose 4,6-dehydratase: gmd

Gene

gmd

Protein

GDP-mannose 4,6 dehydratase

Organism

Dictyostelium discoideum

Length

356 amino acids

Function

Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.

Similarity

Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

Mass

41.061 kDa

Sequence

MSEERKVALITGITGQDGSYLTEFLISKGYYVHGIIQKIFHHFNTIVKNIYIKIDMLKEKESLTLHYGDLTDASNLHSIVSKVNPTEIYNLGAQSHVKVSFDMSEYTGDVDGLGCLRLLDAIRSCGMEKKVKYYQASTSELYGKVQEIPQSETTPFYPRSPYAVAKQYAYWIVVNYREAYDMYACNGILFNHESPRRGPTFVTRKITRFVAGIACGRDEILYLGNINAKRDWGHARDYVEAMWLMLQQEKPEDFVIATGETHSVREFVEKSFKEIDIIIKWRGEAEKEEGYCEKTGKVYVKIDEKYYRPTEVDLLLGNPNKAKKLLQWQIKTSFGELVKEMVAKDIEYIKNGDKYN

Protein

GDP-mannose 4,6 dehydratase: gmd

Gene

gmd

Protein

GDP-mannose 4,6-dehydratase

Organism

Rhizobium fredii (strain HH103)

Length

351 amino acids

Function

Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.

Similarity

Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

Mass

40.014 kDa

Sequence

MTDRKVALISGVTGQDGAYLAELLLDEGYIVHGIKRRSSSFNTQRIEHIYQERHDPEARFFLHYGDMTDSTNLLRIVQQTQPHEIYNLAAQSHVQVSFETPEYTANADAIGTLRMLEAIRILGLIHRTRFYQASTSELYGLAQEIPQNEKTPFYPRSPYAAAKLYAYWIVVNYREAYGMHASNGILFNHESPLRGETFVTRKITRAAAAISLGKQEVLYLGNLDAQRDWGHAREYVRGMWMMCQQDRPGDYVLATGVTTSVRTFVEWAFEETGMTIEWVGEGIEERGIDAATGKCVVAVDPRYFRPTEVDLLLGDATKARQVLGWRHETSVRDLACEMVREDLSYLRGTRQ

Protein

GDP-mannose 4,6-dehydratase: gmd

Gene

gmd

Protein

GDP-mannose 4,6-dehydratase

Organism

Sinorhizobium fredii (strain NBRC 101917 / NGR234)

Length

351 amino acids

Function

Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.

Similarity

Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

Mass

39.981 kDa

Sequence

MTDRKVALISGVTGQDGAYLAELLLDEGYIVHGIKRRSSSFNTQRIEHIYQERHDPEARFFLHYGDMTDSTNLLRIVQQTQPHEIYNLAAQSHVQVSFETPEYTANADAIGTLRMLEAIRILGLTNRTRFYQASTSELYGLAQESPQNEKTPFYPRSPYAAAKLYAYWIVVNYREAYGMHASNGILFNHESPLRGETFVTRKITRAAAAISLGKQEVLYLGNLDAQRDWGHAREYVRGMWMMCQQDRPGDYVLATGVTTSVRTFVEWAFEETGMTIEWVGEGIEERGIDAATGRCVVAVDPRYFRPTEVDLLLGDATKARQVLGWRHETSVRDLACEMVREDLSYLRGTRQ

Protein

GDP-mannose 4,6-dehydratase: gmd

Gene

gmd

Protein

GDP-mannose 4,6-dehydratase

Organism

Aggregatibacter actinomycetemcomitans

Length

344 amino acids

Function

Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.

Similarity

Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

Mass

38.986 kDa

Sequence

MKTAIVTGASGQDGAYLSQLLLDKGYKVYATYRRSSSVNLWRIDELNIRNHPNLHLFEFDLTDMSSCISLVTKAQPGEVYNLAAQSFVGVSFSQPVTTAEITAIGVLNLLEAIRIINPKIKFYQASTSEMFGKVQQIPQTEKTPFYPRSPYGVAKLYGHWITLNYRESYDIFGCSGILFNHESPLRGREFVTRKITDTVAKIALNKQSCLELGNLDAKRDWGFAKEYVEGMWRMLQEDQPDTYVLATNRTETVRDFVAMAFQAVNIPLEFNGKGENEIGVNTDTGDVLVRVNKEYYRPAEVDLLIGDYSKAKRILGWEPKTSLEELCKMMIEADIERNKLGFSF

Protein

GDP-mannose 4,6-dehydratase: gmd

Gene

gmd

Protein

GDP-mannose 4,6-dehydratase

Organism

Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

Length

323 amino acids

Function

Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.

Similarity

Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

Mass

36.399 kDa

Sequence

MTRSALVTGITGQDGAYLAKLLLEKGYRVHGLVARRSSDTRWRLRELGIEGDIQYEDGDMADACSVQRAVIKAQPQEVYNLAAQSFVGASWNQPVTTGVVDGLGVTHLLEAIRQFSPETRFYQASTSEMFGLIQAERQDENTPFYPRSPYGVAKLYGHWITVNYRESFGLHASSGILFNHESPLRGIEFVTRKVTDAVARIKLGKQQELRLGNVDAKRDWGFAGDYVEAMWLMLQQDKADDYVVATGVTTTVRDMCQIAFEHVGLDYRDFLKIDPAFFRPAEVDVLLGNPAKAQRVLGWKPRTSLDELIRMMVEADLRRVSRE

Protein

GDP-mannose 4,6-dehydratase: gmd