glyA2

Serine hydroxymethyltransferase 2

437 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

47.991 kDa

MAEPGTYGRSSLVQVDCRVHELLLRQRRQERTMLKLIASENFASSAVLEATGSIFANKYAEGYPGARYYAGNEIVDELETLAIERLKALFGSEHANVQPYSGSPANQAVYRALLSPRDKVMGLPLPEGGHLTHGWSVNFSGTDYQRVPYGLHDKTQQIDYDRLRETARRERPKLIWVGGTSYPRVFDYAAMAEIALEANSYLVADIAHISGLIVAGAHPNPVVHCDVVTSTSHKSIRGPRGGFILSKNEDRYQALYHSTSKHNLAKRIDRAVFPQLQGGPHMNTIAALAVALQEAATPSFRTYGHQIVKNAKALAEALLGRGYYLVTGGTDNHMLILDLRDRPLSGKAYAERLARAGIITNFDMVPGDPRDPTVTSGIRLGSPAVTSMGMREAEMVQIAAFIDSVCRQPDDQEVHASVRRDVADFCTAFDVPGISDR

glyA2

Serine hydroxymethyltransferase 2

435 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

46.911 kDa

MNANLNKAYPNVSLENFFSTPLAATNDAVFAAIQAEYTRQNEQIELIASENIVSKAVMQAQGTCLTNKYAEGYPGRRYYGGCEHVDSVEQIAIERAKMLFQCQYANVQPHSGAQANGAVMLALLQPGDTIMGMSLDAGGHLTHGARPALSGKWFNAVQYGVDRQTLEINYDSVRALALEHKPKMIIAGGSAIPRTIDFAQFRSIVDEVGALLMVDMAHIAGLVATGAHPSPLPHAHVVTTTTHKTLRGPRGGMILTNSEEIHKKINSAVFPGLQGGPLMHVIAAKAVAFGEALGPEFRTYIDSVIDNAKVLAEVLQTRGCDIVTGGTDTHLMLVDLRPKGLKGNQVEQALERAGITCNKNGIPFDEEKPMITSGIRLGTPAGTSRGFGREEFKLIGEWIGDVLDGLVASPEGNPDVEQQVRKQVKALCQRFPLYQ

glyA2

Serine hydroxymethyltransferase 2

434 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

45.36 kDa

MGPSVAPHAVHTIANPGVSAAGLVAADHAVAAAIADEETRQRDSIELIASENFVSRAVLDAQGSVLTNKYAEGYPHRRYYGGCANVDAIEDLVIARVNQLFGSAYANVQPHSGSQANQAVFLALLAPGDTILGLDLKAGGHLTHGAPVNMSGRWFKAVSYGVDPETHRIDMDQVAVQARQHRPRLLIAGGSAYPRIIDFGRFRQIADEVGAILMVDMAHFAGLVAGGVYPSPVPFADVVTSTTHKTLRGPRGGFVLTNDANIAKKINSATFPGLQGGPLMHVIAAKAVAFGEALQPEFGAYAQAVVENCRVLAQALADGGLTITSGGTDCHLAVVDLRPFGVTGNIAEQALESVGITLNKNAIPNDPEKPMVTSGIRVGTAAGTSRGFGADQYREIAGLVLETLHAVRAGTLDAAGQEINKSVRRLAASFPLPY

glyA2

Serine hydroxymethyltransferase 2

431 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

46.507 kDa

MNKSYPNHSLENFFSTNLSATDDAVFAGIQAEFTRQNEQIELIASENIVSKAVMQAQGTCLTNKYAEGYPGRRYYGGCEHVDTVEAIAIERAKKLFNCEYANVQPHSGAQANGAVKLALLQPGDTILGMSLDAGGHLTHGARPALSGKWFNAVQYGVDRETLEINYDDVRALALEHKPKMIIAGGSAIPRTIDFAKFREIADEVNAILMVDMAHIAGLIATGAHPSPLPHAHVVTTTTHKTLRGPRGGMILTNHEDIIKKINSAVFPGLQGGPLMHVIAAKAVAFGEALGPEFKTYIDSVINNAKVLAEVLQTRGCDIVTGGTDTHLMLVDLRPKGLKGNKAEEALERAGITCNKNGIPFDTEKPMITSGIRLGTPAGTSRGFGAEEFKLIGNWIGDVLDGLVNNPEGDAIVEKRVRKEVKELCSRFPLYQ

glyA2

Serine hydroxymethyltransferase 2

431 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

46.46 kDa

MNSHYQNHSLENFFSTNLSATDDAVFAGIQAEFTRQNEQIELIASENIVSKAVMQAQGTCLTNKYAEGYPGRRYYGGCEHVDTVEAIAIERAKKLFNCEYANVQPHSGAQANGAVKLALLQPGDTIMGMSLDAGGHLTHGARPALSGKWFNAVQYGVDKETLEINYDDVRALAVEHKPKMIIAGGSAIPRVIDFAKFREIADEVGAILMVDMAHIAGLIATGAHPSPLPHAHVVTTTTHKTLRGPRGGMILTNHEEIIKKINSAVFPGLQGGPLMHVIAAKAVAFGEALGPEFKTYIDSVIDNAKVLAEVLQTRGCDIVTGGTDTHLMLVDLRPKGLKGNKAEEALERAGITCNKNGIPFDTEKPMITSGVRLGTPAGTSRGFGAEEFKLIGHWIGDVLDGLVENPEGNAEVEQRVRKEVKALCSRFPLYQ

glyA2

Serine hydroxymethyltransferase 2

431 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

46.459 kDa

MNSHYQNHSLENFFSTNLSATDDAVFAGIQAEFTRQNEQIELIASENIVSKAVMQAQGTCLTNKYAEGYPGRRYYGGCEHVDTVEAIAIERAKKLFNCEYANVQPHSGAQANGAVKLALLQPGDTIMGMSLDAGGHLTHGARPALSGKWFNAVQYGVDKETLEINYDDVRALAVEHKPKMIIAGGSAIPRVIDFAKFREIADEVGAILMVDMAHIAGLIATGAHPSPLPHAHVVTTTTHKTLRGPRGGMILTNHEEIIKKINSAVFPGLQGGPLMHVIAAKAVAFGEALGPEFKTYIDSVINNAKVLAEVLQTRGCDIVTGGTDTHLMLVDLRPKGLKGNKAEEALERAGITCNKNGIPFDTEKPMITSGVRLGTPAGTSRGFGAEEFKLIGHWIGDVLDGLVENPEGNAEVEQRVRKEVKALCSRFPLYQ

glyA2

Serine hydroxymethyltransferase 2

431 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

46.611 kDa

MKASYQNHDLEMFFSTNLAQVDGAVNAGIEAELNRQNQQIELIASENIVSKAVMQAQGTCLTNKYAEGYAGHRYYGGCEHVDEVEKIAIARAKQLFQCEYVNVQPHSGAQANGAVMLALLQPGDTILGMSLDAGGHLTHGARPALSGKWFDAVQYGVNKDTLEIDYNQVRELAIEHKPKMIIAGGSAIPRIINFAKFREIADEVGAFLMVDMAHIAGLIAAGEHPSPIPHAHVITTTTHKTLRGPRGGMILTNLEDINKKINSAVFPGLQGGPLMHVIAGKAVAFGEALEPDFKIYIKNVISNAKVLAEVLQNRGCDIVTNGTDTHLMLVDLRPKGLKGNAAENALERAGITCNKNGIPFDTEKPMVTSGIRLGTPAGTSRGFGNDEFKQIGEWIGDVLDGLAANPEDNSEVEKHVKQQVQKLCSRFPLYQ

glyA2

Serine hydroxymethyltransferase 2

430 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

45.352 kDa

MTAYTPWTGFFSASVAQADPELDRVLRAELSRQQDQIELIASENIVSRAVLEAAGSVLTNKYAEGYPGKRYYGGCEEVDVAEELAIERAKALFGCSYVNVQPHSGAQANGAVMMALVKPGDTIMGMSLAAGGHLTHGAPPAQSGKWFNAVQYGVRLQDASIDFDEVATLAETHKPKLIIAGGSAYPRIIDFAKFREIADRVGALFMVDMAHFAGLVAAGLHPSPLPYADIVTTTTHKTLRGPRGGMVLSNNPDIGKKINSAVFPGLQGGPLMHIIAAKAVAFGEALRPEFKVYAQAVIDNAKALTDALAAGGLNIVSGGTDTHLALVDLRPKALTGNIVEKSLERANITTNKNGIPFDPEKPAITSGIRVGTPAGTTRGFGTAEFTEIGKLIVEVLDGLAANGEDNSQAEAAVREKVAVLCRRFPIYGGL

glyA2

Serine hydroxymethyltransferase 2

425 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

45.454 kDa

MNTLNDSLTAFDPDIAALIDGELRRQESGLEMIASENYAPLAVMQAQGSVLTNKYAEGYPGRRYYGGCEFVDGVEQLAIDRVKALFGAEYANVQPHSGATANAATMHALLNPGDTILGLSLAHGGHLTHGMRINFSGKLYHATAYEVSKEDYLVDMDAVAEAARTHRPKMIIAGWSAYPRQLDFARFRAIADEVDAVLMVDMAHFAGLVAAGVHPSPVPHAHVVTSTTHKTLGGPRGGIILCNDPAIAKKINSAVFPGQQGGPLGHVIAAKATAFKMAAQPEFAQRQQRCLDGARILAGRLTQPDVAERGIAVLTGGTDVHLVLVDLRDAELDGQQAEDRLAAVDITVNRNAVPFDPRPPMITSGLRIGTPALAARGFSHNDFRAVADLIAAALTATNDDQLGPLRAQVQRLAARYPLYPELHRT

glyA2

Serine hydroxymethyltransferase 2

425 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules (By similarity).

Belongs to the SHMT family.

45.526 kDa

MNTLNDSLTAFDPDIAALIDGELRRQESGLEMIASENYAPLAVMQAQGSVLTNKYAEGYPGRRYYGGCEFVDGVEQLAIDRVKALFGAEYANVQPHSGATANAATMHALLNPGDTILGLSLAHGGHLTHGMRINFSGKLYHATAYEVSKEDYLVDMDAVAEAARTHRPKMIIAGWSAYPRQLDFARFRAIADEVDAVLMVDMAHFAGLVAAGVHPSPVPHAHVVTSTTHKTLGGPRGGIILCNDPAIAKKINSAVFPGQQGGPLEHVIAAKATAFKMAAQPEFAQRQQRCLDGARILAGRLTQPDVAERGIAVLTGGTDVHLVLVDLRDAELDGQQAEDRLAAVDITVNRNAVPFDPRPPMITSGLRIGTPALAARGFSHNDFRAVADLIAAALTATNDDQLGPLRAQVQRLAARYPLYPELHRT

glyA2

Serine hydroxymethyltransferase 2

425 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Thus, is able to catalyze the cleavage of L-allo-threonine.

Belongs to the SHMT family.

45.526 kDa

MNTLNDSLTAFDPDIAALIDGELRRQESGLEMIASENYAPLAVMQAQGSVLTNKYAEGYPGRRYYGGCEFVDGVEQLAIDRVKALFGAEYANVQPHSGATANAATMHALLNPGDTILGLSLAHGGHLTHGMRINFSGKLYHATAYEVSKEDYLVDMDAVAEAARTHRPKMIIAGWSAYPRQLDFARFRAIADEVDAVLMVDMAHFAGLVAAGVHPSPVPHAHVVTSTTHKTLGGPRGGIILCNDPAIAKKINSAVFPGQQGGPLEHVIAAKATAFKMAAQPEFAQRQQRCLDGARILAGRLTQPDVAERGIAVLTGGTDVHLVLVDLRDAELDGQQAEDRLAAVDITVNRNAVPFDPRPPMITSGLRIGTPALAARGFSHNDFRAVADLIAAALTATNDDQLGPLRAQVQRLAARYPLYPELHRT

glyA2

Serine hydroxymethyltransferase 2

424 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

45.422 kDa

MSNANPFFSQSLAERDASVRGAILKELERQQSQVELIASENIVSRAVLDAQGSVLTNKYAEGYPGKRYYGGCEFADEVEALAIERVKRLFNAGHANVQPHSGAQANGAVMLALAKPGDTVLGMSLDAGGHLTHGAKPALSGKWFNALQYGVSRDTMLLDYDQVEALAQQHKPSLIIAGFSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTSTTHKTLRGPRGGFVLTNDEEIAKKINSAVFPGLQGGPLMHVIAGKAVAFGEALTDDFKTYIDHVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVEQALERAGITCNKNGIPFDPEKPTITSGIRLGTPAGTTRGFGAAEFREVGRLILEVFEALRTNPEGDHATEQRVRREIFALCERFPIY

glyA2

Serine hydroxymethyltransferase 2

424 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

45.441 kDa

MSNANPFFSQSLAERDASVRGAILKELERQQSQVELIASENIVSRAVLDAQGSVLTNKYAEGYPGKRYYGGCEFADEVEALAIERVKRLFNAGHANVQPHSGAQANGAVMLALAKPGDTVLGMSLDAGGHLTHGAKPALSGKWFNALQYGVSRDTMLIDYDQVEALAQQHKPSLIIAGFSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTSTTHKTLRGPRGGFVLTNDEEIAKKINSAVFPGLQGGPLMHVIAGKAVAFGEALTDDFKTYIDRVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVEQALERAGITCNKNGIPFDPEKPTITSGIRLGTPAGTTRGFGAAEFREVGRLILEVFEALRTNPEGDHATEQRVRREIFALCERFPIY

glyA2

Serine hydroxymethyltransferase 2

424 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

45.441 kDa

MSNANPFFSQSLAERDASVRGAILKELERQQSQVELIASENIVSRAVLDAQGSVLTNKYAEGYPGKRYYGGCEFADEVEALAIERVKRLFNAGHANVQPHSGAQANGAVMLALAKPGDTVLGMSLDAGGHLTHGAKPALSGKWFNALQYGVSRDTMLIDYDQVEALAQQHKPSLIIAGFSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTSTTHKTLRGPRGGFVLTNDEEIAKKINSAVFPGLQGGPLMHVIAGKAVAFGEALTDDFKTYIDRVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVEQALERAGITCNKNGIPFDPEKPTITSGIRLGTPAGTTRGFGAAEFREVGRLILEVFEALRTNPEGDHATEQRVRREIFALCERFPIY

glyA2

Serine hydroxymethyltransferase 2

424 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

45.361 kDa

MSNANPFFSQSLAERDASVRGAILKELERQQSQVELIASENIVSRAVLDAQGSVLTNKYAEGYPGKRYYGGCEFADEVEALAIDRVKQIFNAGHANVQPHSGAQANGAVMLALAKPGDTVLGMSLDAGGHLTHGAKPALSGKWFNAVQYGVSRDTMLIDYDQVEELAQQHKPSLIIAGFSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTSTTHKTLRGPRGGFVLTNDEEIAKKINSAVFPGLQGGPLMHVIAGKAVAFGEALTDDFKTYIDRVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVEQALERSGITCNKNGIPFDAEKPTITSGIRLGTPAGTTRGFGAAEFREVGRLILEVFDALRTNPAGDHATEQRVRREIFALCERFPIY

glyA2

Serine hydroxymethyltransferase 2

424 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

45.617 kDa

MSNTQSFFSQPLAERDALVRGALSKELERQQSQVELIASENIVSRAVLEAQGSVLTNKYAEGYPGKRYYGGCKFADEVESLAIERVKQLFNAGFANVQPHSGAQANGSVMLALTKPGDTVLGMSLDAGGHLTHGAKPALSGKWFNAVQYGVNRESMLIDYDQVEALAKEHKPSLIIAGFSAYPRQLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHSNPVDYAHVVTSTTHKTLRGPRGGFVLTNHEEIAKKINSAVFPGLQGGPLMHVIAAKAVAFGEAMTSDFRTYIDNVLANAKALGEVLKEGGVDLVTGGTDNHLLLVDLRPKGLKGTQVEQALERAGITCNKNGIPFDTEKPTITSGIRLGAPAATTRGFGVAEFREIGRLILEVFEALRANPEGDAVTEQRVRQQIFALCDRFPIY

glyA2

Serine hydroxymethyltransferase 2

424 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

45.667 kDa

MSNTQSFFSQSLAERDAPIRSSLLKELERQQSQVELIASENIVSRAVLEAQGSVLTNKYAEGYPGKRYYGGCEYADEVESLAIDRVKQLFNAGFANVQPHSGAQANGAVMLALTKPGDTVLGMSLDAGGHLTHGAKPALSGKWFNAMQYGVNRDTMLIDYEQVEKLAQEHKPSLIIAGFSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHDNPVDHAHVVTSTTHKTLRGPRGGFVLTNDEEIAKKINSAVFPGLQGGPLMHVIAGKAVAFGEALKPEFKTYIDSVLANAKALGEVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGTQVEQALERAGITCNKNGIPFDTEKPTITSGIRLGTPAATTRGFGVAEFEQIGRLILEVFEALRANPDGDRATEHRVRSEIFALCDRFPIY

glyA2

Serine hydroxymethyltransferase 2

423 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

46.398 kDa

MYDTSLTLTEFDPELADAILHEEDRQETHVELIASENYASPLVMAIQNSVFTNKYAEGYLGKRYYSGCEYVDVAERLAIERAKVLFDCDYANVQPHAGAQANAAVFLALTNPGDTVMGMNLAQGGHLTHGNPSNFSGRHYKIVPYGLDSETGLIDYDEMERIALETRPKMLIGGFSAYSRHKDWARMRTIADKVGAIFWVDMAHVAGLVAAGEYPNPLPQAHVVTSTTHKTLRGPRGGIILAKGQSEDFYKKLNAAVFPGIQGGPLMHVIAAKAVAFKEALRPEFTVYQRQVVANARAMARIIQQRGYKIVSDGTDNHLLLIDLSAKPYTGKDADAALSDAYITTNKNSVPNDPRSPFVTSGLRIGTPAVTTRGFGVTECEQLAGWLCDVLDGLGAGNEELTVIRDRVREQVVALCHRYPVYQ

glyA2

Serine hydroxymethyltransferase 2

422 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

44.776 kDa

MLNRLSHNTVSDTVIADAIAEELDRQKTQIELIASENIVSADVLAAQGSVLTNKYAEGYPGKRYYGGCEFVDKVEQVAIDRLKQLFGAEFANVQPHSGAQANQAVFLALLQPGDRIMGLSLAHGGHLTHGSPVTMSGKWFDVVSYEVDPETHLIDMEKVREKALETKPKLIVAGASAYPRQIDFAGFREIADEVGAYLMVDMAHYAGLIAGGHYPNAVPHAHVTTSTTHKTLRGPRGGVILTNDADLAKKLNSAVFPGNQGGPLMHVIAAKAVAFGEALRPEFSDYAGQVIANAQALAKVLIQGGLGIVSGGTDSHMVLVDLRPKGVTGKIAEIALERAGLTCNKNSIPNDPEKPFVTSGIRLGSSAGTTRGFGVLEFEKIGALILRVIDALATNAEGDSAVEAEVREEVAALCEAFPIYVS

glyA2

Serine hydroxymethyltransferase 2

422 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

44.719 kDa

MPGLFERQLKHDSVIAGAIAREMGRQRSEIELIASENIVSPAVLAAQGSVMTNKYAEGYPGHRYYGGCQYVDLVEAAAIERAGMLFDASFVNVQPHSGAQANGAVMLALLKPGDTFMGLSLAAGGHLTHGARPTMSGKWFNAVQYGVRESDCLIDYDELEVKAIATRPKLIITGGSAYPRLIDFKRIRAIADSVGAAMMVDMAHFAGLVAGGVHPNPVEIADIVTTTTHKTLRGPRGGMILTNNQDVAKKVNSAVFPGLQGGPLMHVIAAKAVALGEALEDNFRQYARQMVANARALASALTERGYDIVSGGTDTHLILVDLRSKGVSGKDAEEALGRAGLTCNKNGIPFDPAPPAVTSGIRLGTPAATSRGFREAEFNEVGALIANVLDALGTEQSGEQERRARMSVHDLCAAFPIYSARH

glyA2

Serine hydroxymethyltransferase 2

420 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

45.706 kDa

MSFISSKSLEHADREVFSIIEGELKRQTAHLEMIASENFTSPAVMEAMGSVFTNKYAEGYPYKRYYGGCEYADAVEQLAIDRACEIFGCKFANVQPHSGSQANAAVYAALLKAGDKLLGMDLSHGGHLTHGSKPSFSGQNYSSFTYGVEADGRMDYDKILEIAKAVQPKIIVCGASAYAREIDFKKFREIADAVGAFLFADIAHVAGLVAADEHMSPFPHAHVVTTTTHKTLRGPRGGMIMTDDEEIAKKINSAIFPGIQGGPLVHVIAAKAVAFKEILDPSWREYAKQVKANAKVLEVVLTKRGYDLVSGGTDNHLVLVSFLNRDFSGKDADAALERAGITVNKNGVPNDTRSPFITSGIRIGSPALTARGMKEAEFELIANKICDVLDNINDTELHVKINKELEELAKGFVIYNKSTF

glyA2

Serine hydroxymethyltransferase 2

419 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

45.558 kDa

MNFRGNRMINNDPLFDLLNKEQQRQQHSLELIASENFASPAVLAAQGSVLTNKYAEGYYQHRYYGGCKFIDEVEMLAITRAQQLFGARYVNVQPHSGSQANQAVYLALLKPGDKILGMSLQCGGHLTHGSPVNQSGKWFNAFHYGVDAHSGLIDMDEVETIAKRERPRLIIAGGSAYPRHYDFARFRRIADAVGAMLLVDMAHFAGLVAGGCFPSPLAYADVITATTHKTLRGPRGGMILTNDARLAKKIDSAIFPGLQGGPLMHVIAAKAVALGEALQPEFKRYAGQVIENAQAMCQQLAQRGLTLLTGGTDCHLGIIDLRPQGLTGAQVEYFLELAGITVNKNTLLGDPQPPSITSGIRIGSAACATRGMKADDFTLIADWISEIIFAIKTPNIADICADIRQKVTKLTTNYPLPYQ

glyA2

Serine hydroxymethyltransferase 2

418 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

45.889 kDa

MFTRDMTIASFDPDLWTAMQGETQRQEEHIELIASENYTSPRVMEAQGSALTNKYAEGYPNKRYYGGCEYVDVVEQLAIDRAKELFGADYANVQPHSGSQANAAVYMALCKPGDVILGMSLAHGGHLTHGASVSFSGRIYKAVQYGLNPETGEIDYEEVAKLARENKPKMIVAGFSAYSRVIDWERFRAIADEVGAYLFVDMAHIAGLVAAGVYPSPVQIADVTTTTTHKTLGGPRGGLILAKANEELEKKLNFAVFPESQGGPLMHVIAAKAVCFKEAMTDEFKQYQAQVVKNARVMADTFIQRGYDIVSGGTDDHLFLVDLIKKDITGKDADAALGRANITVNKNAVPNDPRSPFVTSGLRIGTPAITRRGMGEVEAKELTDWICDVLDDIENEETIQRVKQQVLELCKKFPVYKG

glyA2

Serine hydroxymethyltransferase 2

418 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

44.974 kDa

MFSKHDQLQGYDDELLAAMDAEDRRQEDHIELIASENYASKRVMQAQGGGLTNKYAEGYPGKRYYGGCEHVDKVERLAIDRARQLFGADYANVQPHSGSSANAAVYLALLNAGDTILGMSLAHGGHLTHGAKVSSSGKLYNAVQYGLDTATGLIDYDEVERLAVEHKPKMIVAGFSAYSKTLDFPRFRAIADKVGALLFVDMAHVAGLVAAGLYPNPIPFADVVTTTTHKTLRGPRGGLILARANEEIEKKLNSAVFPGAQGGPLMHVIAAKAVCFKEALEPGFKDYQAQVIRNAKAMAEVFIGRGYDVVSGGTDNHLMLISLVKQGLTGKAADAALGAAHITVNKNAVPNDPQSPFVTSGIRIGTPAVTTRGFREGECRELAGWICDILDDIDNPEVGERVRGQVGEFCRHFPVYAD

glyA2

Serine hydroxymethyltransferase 3

417 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

45.157 kDa

MFSRDLTLARYDAELFAAMEQEAQRQEEHIELIASENYTSPAVMEAQGSVLTNKYAEGYPHKRYYGGCEYVDIVEQLAIDRAKQLFGADYANVQPHAGSQANAAVYLALLSAGDTILGMSLAHGGHLTHGASVSSSGKLYNAVQYGIDANGLIDYDEVERLAVEHKPKMIVAGFSAYSQVLDFARFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRGGLILARANEEIEKKLNSAVFPSAQGGPLEHVIAAKAVCFKEALQPEFKTYQQQVLKNAQSMAQVFLDRGFDVVSGGTQNHLFLLSLIKQDITGKDADAALGRAFITVNKNSVPNDPRSPFVTSGLRIGTPAVTTRGFKEAECRELAGWICDILENMGDESVVDGVREKVKAICAKFPVYGN

glyA2

Serine hydroxymethyltransferase 2

417 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

45.458 kDa

MFYKNDQIAGFDDSIWQAMEQEDKRQQDHVELIASENYTSARVMQAQGSQLTNKYAEGYPGKRYYGGCEHVDVIEQLAIDRAKELFGADYANVQPHSGSQANAAVFMALLKPGETVLGMSLAHGGHLTHGSKVSFSGKIYNAVQYGLNEATGEIDYEEVERLAKEHQPKMIIAGFSAYSRVVDWQRFRDIADSIGAWLFVDMAHVAGLVAAGLYPNPVPIADVVTTTTHKTLRGPRGGLILAKQNDELAKKLNSAVFPAGQGGPLMHVIAAKAICFKEALGEGYVEYQQQVIDNAREMAKTFQTRGYNVVSGGTDNHLFLLDLIDKGITGKDADAALGRANITVNKNSVPNDPQSPFVTSGLRIGTPAITSRGFGLEEAAALTGWICDVLDDISNEQVIDDVRSKVLDLCEKNPVYR

glyA2

Serine hydroxymethyltransferase 2

417 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

44.905 kDa

MFSKQDQIQGYDDALLSAMNAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGGCEHVDKVEQLAIERAKQLFGADYANVQPHSGSQANAAVYLALLQAGDTVLGMSLAHGGHLTHGAKVSFSGKLYNAVQYGIDTTTGLIDYDEVERIAVECQPKMIIAGFSAYSKTLDFPRFREIADKVGAYLFVDMAHVAGLVAAGLYPNPLPYADVVTTTTHKTLRGPRGGLILAKANEELEKKFNSAVFPGGQGGPLMHVIAAKAVCFKEAMEPGFKAYQQQVIDNAQAMAQVFIDRGFDVVSGGTDNHLFLVSLIRQGLTGKDADAALGRAHITVNKNSVPNDPQSPFVTSGLRIGTPAVTTRGFKVTQCVELAGWICDILDNLGDADVEANVASQVAALCADFPVYR

glyA2

Serine hydroxymethyltransferase 2

417 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

44.807 kDa

MFSKQDQIQGYDDALLAAINAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGGCEHVDKVEALAIERAKQLFGADYANVQPHSGSSANSEVYLALLQAGDTILGMSLAHGGHLTHGAKVSSSGKLYNAVQYGIDTRTGLIDYDEVERLAVEHKPKMIVAGFSAYSKTLDFPRFRQIADKVGALLFVDMAHVAGLVAAGLYPNPLPYADVVTTTTHKTLRGPRGGLILAKANEEIEKKLNAAVFPGAQGGPLMHVIAAKAVCFKEALEPGFKAYQQQVIDNAQAMAGVFIKRGYDVVSGGTDNHLFLVSLIRQGLTGKDADAALGRAHITVNKNAVPNDPQSPFVTSGLRIGTPAVTTRGFKVTQCTELAGWICDILDHLGDADVEANVARQVAALCADFPVYR

glyA2

Serine hydroxymethyltransferase 2

417 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

44.795 kDa

MFSRDLTIAKYDADLFAAMEQEAQRQEEHIELIASENYTSPAVMEAQGSVLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRAKELFGADYANVQPHAGSQANAAVYLALLSAGDTILGMSLAHGGHLTHGASVSSSGKLYNAIQYGIDANGLIDYDEVERLAVEHKPKMIVAGFSAYSQILDFPRFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRGGLILAKANADIEKKLNSAVFPGAQGGPLEHVIAAKAICFKEALQPEFKAYQQQVVKNAQAMAGVFIERGFDVVSGGTENHLFLLSLIKQEISGKDADAALGKAFITVNKNSVPNDPRSPFVTSGLRFGTPAVTTRGFKEAECKELAGWICDILADLNNEAVIDAVREKVKAICKKLPVYGA

glyA2

Serine hydroxymethyltransferase 2

417 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

44.897 kDa

MFSRDLTIAKYDAELFEAMQQEALRQEEHIELIASENYTSPAVMEAQGSVLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRAKELFGADYANVQPHAGSQANAAVYLALLSAGDTILGMSLAHGGHLTHGASVSSSGKLYNAIQYGIDGNGLIDYDEVERLAVEHKPKMIVAGFSAYSQVLDFARFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRGGLILARANADIEKKLNSAVFPGAQGGPLEHVIAAKAICFKEALQPEFKAYQQQVVKNAQAMASVFIERGFDVVSGGTQNHLFLLSLIKQEISGKDADAALGKAFITVNKNSVPNDPRSPFVTSGLRFGTPAVTTRGFKEAECKELAGWICDILADLNNEAVIDAVREKVKAICKKLPVYGN

glyA2

Serine hydroxymethyltransferase 2

417 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

44.874 kDa

MFSRDLTIAKYDADLFAAMEQEALRQEEHIELIASENYTSPAVMEAQGSVLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRAKELFGADYANVQPHAGSQANSAVYLALLQGGDTILGMSLAHGGHLTHGASVSSSGKLYNAVQYGIDGNGMIDYDEVERLAVEHKPKMIVAGFSAYSQILDFPRFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRGGLILARANADIEKKLNSAVFPGSQGGPLEHVIAAKAICFKEALQPEFKTYQQQVVKNAKAMAGVFIERGFDVVSGGTENHLFLLSLIKQDISGKDADAALGRAFITVNKNSVPNDPRSPFVTSGLRFGTPAVTTRGFKETECKELAGWICDILADLNNEAVIDAVREKVKAICAKLPVYGA

glyA2

Serine hydroxymethyltransferase 2

417 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

44.874 kDa

MFSKQDQIQGYDDALLSAMNAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGGCEHVDKVEQLAIERARQLFGADYANVQPHSGSQANAAVYLALLQAGDTVLGMSLAHGGHLTHGAKVSFSGKLYNAVQYGIDTATGLIDYDEVERIAVECQPKMIIAGFSAYSKTLDFPRFRAIADKVGAYLFVDMAHVAGLVAAGLYPNPLPYADVVTTTTHKTLRGPRGGLILARANEELEKKFNSAVFPGGQGGPLMHVIAAKAVCFKEAMEPGFKAYQQQVIDNAQAMAQVFIDRGFDVVSGGTDNHLFLVSLIRQGLTGKDADAALGRAHITVNKNSVPNDPQSPFVTSGLRIGTPAVTTRGFKVTQCVELAGWICDILDNLGDADVEADVASQVAALCADFPVYR

glyA2

Serine hydroxymethyltransferase 2

415 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

44.811 kDa

MFNRNLTLDQVDPDVWAAIQKEDVRQEQHIELIASENYASPAVMQAQGTQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRLKQIFGAEAANVQPNSGSQANQGVYMAVLKPGDTVLGMSLAEGGHLTHGASVNASGKLYNFVPYGLDADEVLDYAQVERLTKEHKPKLIVAGASAYALHIDFERMARIAHDNGALFMVDIAHYAGLVAGGAYPNPVPHADFVTSTTHKSLRGPRGGVIMMKAEFEKAVNSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFQDYAQQVVKNAKVLADTLVKRGLRIVSGRTESHVMLVDLRPKGITGKEAEAVLGQAHITVNKNAIPNDPEKPFVTSGIRLGTPAMTTRGFKEAEAELTANLIADVLDNPRDEANIAAVRARVNELTARLPVYGN

glyA2

Serine hydroxymethyltransferase 2

415 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

44.763 kDa

MFNRNLTLDQVDPDVWAAIQKEDVRQEQHIELIASENYASPAVMQAQGTQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRLKQIFGAEAANVQPNSGSQANQGVYMAVLKPGDTVLGMSLAEGGHLTHGASVNASGKLYNFVPYGLDADEVLDYAQVERLTKEHKPKLIVAGASAYALHIDFERMARIAHDNGALFMVDIAHYAGLVAGGAYPNPVPHADFVTSTTHKSLRGPRGGVIMMKAEVEKAVNSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFQDYAQQVVKNAKVLADTLVKRGLRIVSGRTESHVMLVDLRPKGITGKEAEAVLGQAHITVNKNAIPNDPEKPFVTSGIRLGTPAMTTRGFKEAEAELTANLIADVLDNPRDEANIAAVRARVNELTARLPVYGN

glyA2

Serine hydroxymethyltransferase 2

415 amino acids

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

Belongs to the SHMT family.

44.725 kDa

MFNRTTSTVANVDPELYAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRVKQLFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAHGGHLTHGSPVNMSGKWFNVVSYGLNENEDIDYEAAEQLAQEHKPKLIVAGASAFSLKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGGVILMKAEYEKPINSAIFPGIQGGPLMHVIAGKAVAFKEALSPEFKAYQEKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKNITGKAAEAALGAAHITVNKNAIPNDPEKPFVTSGVRLGSPAMTTRGFGVKEAEIVGNLIADVLEAPEDAATLERVRGQVAELTKRFPVYG