get-1

Gene

get-1

Protein

Protein get-1

Organism

Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)

Length

214 amino acids

Function

Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.

Similarity

Belongs to the WRB/GET1 family.

Mass

24.494 kDa

Sequence

MPSLLVVIFVIELFVQLVNTIGAATINNLLWRIALSLPLPLSAQFAAQRKKQKEYLAIRRELNATSSQDEFAKWARLRRQHDKLLEDLEKRKKELDAAKTKFDRTLTTVRVVATRGLQWFLPFWYSREPMFWLPYGWFPYYVEWFASFPRAPLGSVSIVVWQWACTGVIKLVIETVMAVVGLIVAARQKQQEKQKAKQAVPAAGGGDSKAEEAK

Protein

Protein get-1: get-1